Fructose and mannose metabolism

Source	ID	Pathway
KEGG	00051

Pathway Metabolites

YMDB ID	Name CAS Number	IUPAC Name	Formula Weight	Structure
YMDB00011	D-Fructose 2,6-bisphosphate	{[(2R,3S,4S,5S)-3,4-dihydroxy-5-(hydroxymethyl)-5-(phosphonooxy)oxolan-2-yl]methoxy}phosphonic acid	C₆H₁₄O₁₂P₂ 340.1157
YMDB00111	D-Lactaldehyde 3946-09-6	(2R)-2-hydroxypropanal	C₃H₆O₂ 74.0785
YMDB00115	D-Glyceraldehyde 3-phosphate 142-10-9	(2-hydroxy-3-oxopropoxy)phosphonic acid	C₃H₇O₆P 170.0578
YMDB00167	Lactaldehyde 598-35-6	(2S)-2-hydroxypropanal	C₃H₆O₂ 74.0785
YMDB00202	Guanosine diphosphate mannose 3123-67-9	[({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]({[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy})phosphinic acid	C₁₆H₂₅N₅O₁₆P₂ 605.3411
YMDB00204	L-Sorbose 87-79-6	(2R,3S,4R,5S)-2-(hydroxymethyl)oxane-2,3,4,5-tetrol	C₆H₁₂O₆ 180.1559
YMDB00242	Mannose 6-phosphate 3672-15-9	{[(2R,3S,4S,5S,6R)-3,4,5,6-tetrahydroxyoxan-2-yl]methoxy}phosphonic acid	C₆H₁₃O₉P 260.1358
YMDB00273	Alpha-D-Glucose 492-62-6	(2S,3R,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol	C₆H₁₂O₆ 180.1559
YMDB00322	Dihydroxyacetone phosphate 57-04-5	(3-hydroxy-2-oxopropoxy)phosphonic acid	C₃H₇O₆P 170.0578
YMDB00575	D-glyceraldehyde 453-17-8	(2R)-2,3-dihydroxypropanal	C₃H₆O₃ 90.0779
YMDB00656	D-glucitol 50-70-4	(2R,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol	C₆H₁₄O₆ 182.1718
YMDB00657	D-Fructose 57-48-7	(3S,4R,5R)-1,3,4,5,6-pentahydroxyhexan-2-one	C₆H₁₂O₆ 180.1559
YMDB00830	D-mannitol 69-65-8	(2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol	C₆H₁₄O₆ 182.1718
YMDB00831	alpha-D-mannose 1-phosphate 27251-84-9	{[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phosphonic acid	C₆H₁₃O₉P 260.1358
YMDB00878	D-fructofuranose 2-phosphate 108102-98-3	{[(3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy}phosphonic acid	C₆H₁₃O₉P 260.1358
YMDB00894	D-Mannose 3458-28-4	(3S,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol	C₆H₁₂O₆ 180.1559
YMDB00966	D-mannose 6-phosphate 3672-15-9	{[(2R,3S,4S,5S)-3,4,5,6-tetrahydroxyoxan-2-yl]methoxy}phosphonic acid	C₆H₁₃O₉P 260.1358

Pathway Proteins

Uniprot ID	Gene Name Locus	Name	Type	Metabolites
P32604	FBP26 YJL155C	Fructose-2,6-bisphosphatase	Enzyme	D-Fructose 2,6-bisphosphate Fructose 6-phosphate water phosphate β-D-fructofuranose 6-phosphate
Q12471	PFK27 YOL136C	6-phosphofructo-2-kinase 2	Enzyme	D-Fructose 2,6-bisphosphate Fructose 6-phosphate Adenosine triphosphate hydron ADP β-D-fructofuranose 6-phosphate
Q06137	YLR345W	Putative 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase YLR345W	Enzyme	D-Fructose 2,6-bisphosphate Fructose 6-phosphate Adenosine triphosphate water phosphate ADP
P40433	PFK26 YIL107C	6-phosphofructo-2-kinase 1	Enzyme	D-Fructose 2,6-bisphosphate Fructose 6-phosphate Adenosine triphosphate hydron ADP β-D-fructofuranose 6-phosphate
P04807	HXK2 YGL253W	Hexokinase-2	Enzyme	D-Galactose Fructose 6-phosphate Adenosine triphosphate Mannose 6-phosphate D-Glucose aldehydo-D-glucose 6-phosphate D-fructose 1-phosphate D-Fructose hydron D-Mannose ADP Glucose 6-phosphate D-mannose 6-phosphate Beta-D-Fructose 6-phosphate
Q06204	YLR446W	Putative hexokinase YLR446W	Enzyme	D-Galactose Adenosine triphosphate Mannose 6-phosphate D-Fructose D-Mannose ADP Glucose 6-phosphate Beta-D-Fructose 6-phosphate
P04806	HXK1 YFR053C	Hexokinase-1	Enzyme	D-Galactose Fructose 6-phosphate Adenosine triphosphate Mannose 6-phosphate D-Glucose aldehydo-D-glucose 6-phosphate D-fructose 1-phosphate D-Fructose hydron D-Mannose ADP Glucose 6-phosphate D-mannose 6-phosphate Beta-D-Fructose 6-phosphate
P29952	PMI40 YER003C	Mannose-6-phosphate isomerase	Enzyme	Fructose 6-phosphate Mannose 6-phosphate D-mannose 6-phosphate Beta-D-Fructose 6-phosphate
P16861	PFK1 YGR240C	6-phosphofructokinase subunit alpha	Enzyme	Fructose 6-phosphate Fructose 1,6-bisphosphate Adenosine triphosphate D-fructose 1,6-bisphosphate hydron ADP
P16862	PFK2 YMR205C	6-phosphofructokinase subunit beta	Enzyme	Fructose 6-phosphate Fructose 1,6-bisphosphate Adenosine triphosphate D-fructose 1,6-bisphosphate ADP
P09201	FBP1 YLR377C	Fructose-1,6-bisphosphatase	Enzyme	Fructose 6-phosphate Fructose 1,6-bisphosphate D-fructose 1,6-bisphosphate water phosphate
P35497	SOR1 YJR159W	Sorbitol dehydrogenase 1	Enzyme	L-Iditol NAD NADH L-Sorbose NAD(+) D-glucitol D-Fructose L-glucitol hydron keto-D-fructose
Q07786	SOR2 YDL246C	Sorbitol dehydrogenase 2	Enzyme	L-Iditol NAD NADH L-Sorbose
P14540	FBA1 YKL060C	Fructose-bisphosphate aldolase	Enzyme	Fructose 1,6-bisphosphate D-Glyceraldehyde 3-phosphate D-Erythrose 4-phosphate Dihydroxyacetone phosphate D-glyceraldehyde D-fructose 1-phosphate D-fructose 1,6-bisphosphate sedoheptulose 1,7-bisphosphate
P38715	GRE3 YHR104W	NADPH-dependent aldose reductase GRE3	Enzyme	D-Lactaldehyde Lactaldehyde Pyruvaldehyde Glycerol D-Glucose D-Xylitol NADPH NADP D-glyceraldehyde L-arabinitol D-glucitol Xylitol aldehydo-D-Xylose hydron L-Arabinose
P00942	TPI1 YDR050C	Triosephosphate isomerase	Enzyme	D-Glyceraldehyde 3-phosphate Dihydroxyacetone phosphate
P41940	MPG1 YDL055C	Mannose-1-phosphate guanyltransferase	Enzyme	Guanosine diphosphate mannose Pyrophosphate D-Mannose 1-phosphate GTP alpha-D-mannose 1-phosphate hydron
P07283	SEC53 YFL045C	Phosphomannomutase	Enzyme	Mannose 6-phosphate D-Mannose 1-phosphate D-mannose 6-phosphate