{"ymdb_id":"YMDB00223","created_at":"2011-05-29T16:08:39.000Z","updated_at":"2016-09-08T18:35:12.000Z","name":"D-Erythrose 4-phosphate","cas":"585-18-2","state":"Solid","melting_point":"","description":"D-Erythrose 4-phosphate is a phosphorylated derivative of erythrose that serves as an important intermediate in the pentose phosphate pathway.  It is also used in phenylalanine, tyrosine and tryptophan biosynthesis, and it plays a role in vitamin B6 metabolism. [KEGG]","experimental_water_solubility":"","experimental_logp_hydrophobicity":"","location":"mitochondrion;cytoplasm","synthesis_reference":null,"chebi_id":"48153","hmdb_id":"HMDB01321","kegg_id":"C00279","pubchem_id":"697","cs_id":null,"foodb_id":null,"wikipedia_link":"erythrose-4-phosphate","biocyc_id":"ERYTHROSE-4P","iupac":"[(2R,3R)-2,3-dihydroxy-4-oxobutoxy]phosphonic acid","traditional_iupac":"4-O-phosphono-D-erythrose","logp":"-2.431256710333334","pka":"6.505414511121815","alogps_solubility":"2.37e+01 g/l","alogps_logp":"-1.89","alogps_logs":"-0.93","acceptor_count":"6","donor_count":"4","rotatable_bond_count":"5","polar_surface_area":"124.29000000000002","refractivity":"36.2935","polarizability":"15.408046810674074","formal_charge":"0","physiological_charge":"-2","pka_strongest_basic":"-3.5741525769148197","pka_strongest_acidic":"1.479591569624267","bioavailability":"1","number_of_rings":"0","rule_of_five":"1","ghose_filter":"0","veber_rule":"0","mddr_like_rule":"0","synonyms":["4-O-phosphonato-D-erythrose","D-Erythrose 4-phosphate","D-Erythrose 4-phosphic acid","D-Erythrose 4-PO4","D-erythrose-4-P","D-erythrose-4-phosphate","Erythrose 4-phosphate","Erythrose 4-PO4","erythrose-4-P","erythrose-4-phosphate","erythrose-4P","threose 4-phosphate"],"pathways":[{"name":"Pentose phosphate pathway","kegg_map_id":"00030"},{"name":"Vitamin B6 metabolism","kegg_map_id":"00750"},{"name":"Phenylalanine, tyrosine and tryptophan biosynthesis","kegg_map_id":"00400"},{"name":"Riboneogenesis","kegg_map_id":null},{"name":"Vitamin B6","kegg_map_id":null},{"name":"xylitol degradation","kegg_map_id":null}],"growth_conditions":[],"references":[{"pubmed_id":21051339,"citation":"UniProt Consortium (2011). \"Ongoing and future developments at the Universal Protein Resource.\" Nucleic Acids Res 39:D214-D219."},{"pubmed_id":21062828,"citation":"Scheer, M., Grote, A., Chang, A., Schomburg, I., Munaretto, C., Rother, M., Sohngen, C., Stelzer, M., Thiele, J., Schomburg, D. (2011). \"BRENDA, the enzyme information system in 2011.\" Nucleic Acids Res 39:D670-D676."},{"pubmed_id":18846089,"citation":"Herrgard, M. J., Swainston, N., Dobson, P., Dunn, W. B., Arga, K. Y., Arvas, M., Bluthgen, N., Borger, S., Costenoble, R., Heinemann, M., Hucka, M., Le Novere, N., Li, P., Liebermeister, W., Mo, M. L., Oliveira, A. P., Petranovic, D., Pettifer, S., Simeonidis, E., Smallbone, K., Spasic, I., Weichart, D., Brent, R., Broomhead, D. S., Westerhoff, H. V., Kirdar, B., Penttila, M., Klipp, E., Palsson, B. O., Sauer, U., Oliver, S. G., Mendes, P., Nielsen, J., Kell, D. B. (2008). \"A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology.\" Nat Biotechnol 26:1155-1160."},{"pubmed_id":10935926,"citation":"Vaseghi, S., Baumeister, A., Rizzi, M., Reuss, M. (1999). \"In vivo dynamics of the pentose phosphate pathway in Saccharomyces cerevisiae.\" Metab Eng 1:128-140."},{"pubmed_id":1943992,"citation":"Braus, G. H. (1991). \"Aromatic amino acid biosynthesis in the yeast Saccharomyces cerevisiae: a model system for the regulation of a eukaryotic biosynthetic pathway.\" Microbiol Rev 55:349-370."},{"pubmed_id":2880280,"citation":"Teshiba, S., Furter, R., Niederberger, P., Braus, G., Paravicini, G., Hutter, R. (1986). \"Cloning of the ARO3 gene of Saccharomyces cerevisiae and its regulation.\" Mol Gen Genet 205:353-357."},{"pubmed_id":8300619,"citation":"Banki, K., Halladay, D., Perl, A. (1994). \"Cloning and expression of the human gene for transaldolase. A novel highly repetitive element constitutes an integral part of the coding sequence.\" J Biol Chem 269:2847-2851."}],"proteins":[{"created_at":"2011-05-24T20:48:15.000Z","updated_at":"2011-07-22T17:53:45.000Z","name":"Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited","uniprot_id":"P32449","uniprot_name":"AROG_YEAST","enzyme":true,"transporter":false,"gene_name":"ARO4","num_residues":370,"molecular_weight":"39748.80078","theoretical_pi":"6.94","general_function":"Involved in catalytic activity","specific_function":"Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)","reactions":[{"id":1143,"direction":"\u003e","locations":"mitochondrion;cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":2348,"direction":"\u003e","locations":"","altext":"Phosphoenolpyruvate + D-erythrose 4-phosphate + H(2)O = 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate + phosphate.","export":false,"pw_reaction_id":null,"source":null}],"signal_regions":"None","transmembrane_regions":"None","pdb_id":"1OF6","cellular_location":null,"genbank_gene_id":"X61107","genbank_protein_id":"433966","gene_card_id":"ARO4","chromosome_location":"chromosome 2","locus":"YBR249C","synonyms":["3-deoxy-D-arabino-heptulosonate 7-phosphate synthase","DAHP synthase","Phospho-2-keto-3-deoxyheptonate aldolase"],"enzyme_classes":["2.5.1.54"],"go_classes":[{"category":"Component","description":" Not Available"},{"category":"Function","description":" catalytic activity"},{"category":"Function","description":" transferase activity"},{"category":"Function","description":" transferase activity, transferring alkyl or aryl (other than methyl) groups"},{"category":"Function","description":" 3-deoxy-7-phosphoheptulonate synthase activity"},{"category":"Process","description":" metabolic process"},{"category":"Process","description":" biosynthetic process"},{"category":"Process","description":" cellular metabolic process"},{"category":"Process","description":" cellular amino acid and derivative metabolic process"},{"category":"Process","description":" cellular amino acid metabolic process"},{"category":"Process","description":" cellular amino acid biosynthetic process"},{"category":"Process","description":" aromatic amino acid family biosynthetic process"}],"pfams":[{"name":"DAHP_synth_1","identifier":"PF00793"}],"pathways":[{"name":"Phenylalanine, tyrosine and tryptophan 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aldolase, phenylalanine-inhibited","uniprot_id":"P14843","uniprot_name":"AROF_YEAST","enzyme":true,"transporter":false,"gene_name":"ARO3","num_residues":370,"molecular_weight":"41069.5","theoretical_pi":"7.44","general_function":"Involved in catalytic activity","specific_function":"Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)","reactions":[{"id":1143,"direction":"\u003e","locations":"mitochondrion;cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":2348,"direction":"\u003e","locations":"","altext":"Phosphoenolpyruvate + D-erythrose 4-phosphate + H(2)O = 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate + phosphate.","export":false,"pw_reaction_id":null,"source":null}],"signal_regions":"None","transmembrane_regions":"None","pdb_id":null,"cellular_location":null,"genbank_gene_id":"AY557657","genbank_protein_id":"45269207","gene_card_id":"ARO3","chromosome_location":"chromosome 4","locus":"YDR035W","synonyms":["3-deoxy-D-arabino-heptulosonate 7-phosphate synthase","DAHP synthase","Phospho-2-keto-3-deoxyheptonate aldolase"],"enzyme_classes":["2.5.1.54"],"go_classes":[{"category":"Component","description":" Not Available"},{"category":"Function","description":" catalytic activity"},{"category":"Function","description":" transferase activity"},{"category":"Function","description":" transferase activity, transferring alkyl or aryl (other than methyl) groups"},{"category":"Function","description":" 3-deoxy-7-phosphoheptulonate synthase activity"},{"category":"Process","description":" metabolic process"},{"category":"Process","description":" biosynthetic process"},{"category":"Process","description":" cellular metabolic process"},{"category":"Process","description":" cellular amino acid and derivative metabolic process"},{"category":"Process","description":" cellular amino acid metabolic process"},{"category":"Process","description":" cellular amino acid biosynthetic process"},{"category":"Process","description":" aromatic amino acid family biosynthetic process"}],"pfams":[{"name":"DAHP_synth_1","identifier":"PF00793"}],"pathways":[{"name":"Phenylalanine, tyrosine and tryptophan 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2","uniprot_id":"P33315","uniprot_name":"TKT2_YEAST","enzyme":true,"transporter":false,"gene_name":"TKL2","num_residues":681,"molecular_weight":"75028.79688","theoretical_pi":"6.05","general_function":"Involved in catalytic activity","specific_function":"Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate","reactions":[{"id":2017,"direction":"\u003c\u003e","locations":"cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":2018,"direction":"\u003c\u003e","locations":"cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":2477,"direction":"\u003e","locations":"","altext":"Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate.","export":false,"pw_reaction_id":null,"source":null},{"id":14085,"direction":"\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R006510","source":"Smpdb"},{"id":14086,"direction":"\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R006512","source":"Smpdb"},{"id":14087,"direction":"\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R006513","source":"Smpdb"},{"id":14088,"direction":"\u003c\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R007089","source":"Smpdb"},{"id":14089,"direction":"\u003c\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R007092","source":"Smpdb"}],"signal_regions":"None","transmembrane_regions":"None","pdb_id":null,"cellular_location":null,"genbank_gene_id":"X73532","genbank_protein_id":"313262","gene_card_id":"TKL2","chromosome_location":"chromosome 2","locus":"YBR117C","synonyms":["TK 2"],"enzyme_classes":["2.2.1.1"],"go_classes":[{"category":"Component","description":" Not Available"},{"category":"Function","description":" catalytic activity"},{"category":"Function","description":" transferase activity"},{"category":"Function","description":" transferase activity, transferring aldehyde or ketonic groups"},{"category":"Function","description":" transketolase activity"},{"category":"Process","description":" metabolic process"}],"pfams":[{"name":"Transket_pyr","identifier":"PF02779"},{"name":"Transketolase_C","identifier":"PF02780"},{"name":"Transketolase_N","identifier":"PF00456"}],"pathways":[{"name":"Pentose phosphate pathway","kegg_map_id":"00030"},{"name":"Riboneogenesis","kegg_map_id":null},{"name":"xylitol degradation","kegg_map_id":null}],"gene_sequence":"ATGGCACAGTTCTCCGACATTGATAAACTTGCGGTTTCCACTTTAAGATTACTTTCCGTTGACCAGGTGGAAAGCGCACAATCTGGCCACCCAGGTGCACCACTAGGATTGGCACCAGTTGCCCATGTAATTTTCAAGCAACTGCGCTGTAACCCTAACAATGAACATTGGATCAATAGAGACAGGTTTGTTCTGTCGAACGGTCACTCATGCGCTCTTCTGTACTCAATGCTCCATCTATTAGGATACGATTACTCTATCGAGGACTTGAGACAATTTAGACAAGTAAACTCAAGGACACCGGGTCATCCAGAATTCCACTCAGCGGGAGTGGAAATCACTTCCGGTCCGCTAGGCCAGGGTATCTCAAATGCTGTTGGTATGGCAATAGCGCAGGCCAACTTTGCCGCCACTTATAACGAGGATGGCTTTCCCATTTCCGACTCATATACGTTTGCTATTGTAGGGGATGGTTGCTTACAAGAGGGTGTTTCTTCGGAGACCTCTTCCTTAGCGGGACATCTGCAATTGGGTAACTTGATTACGTTTTATGACAGTAATAGCATTTCCATTGACGGTAAAACCTCGTACTCGTTCGACGAAGATGTTTTGAAGCGATACGAGGCATATGGTTGGGAAGTCATGGAAGTCGATAAAGGAGACGACGATATGGAATCCATTTCTAGCGCTTTGGAAAAGGCAAAACTATCGAAGGACAAGCCAACCATAATCAAGGTAACTACTACAATTGGATTTGGGTCCCTACAACAGGGTACTGCTGGTGTTCATGGGTCCGCTTTGAAGGCAGATGATGTTAAACAGTTGAAGAAGAGGTGGGGGTTTGACCCAAATAAATCATTTGTAGTACCTCAAGAGGTGTACGATTATTATAAGAAGACTGTTGTGGAACCCGGTCAAAAACTTAATGAGGAATGGGATAGGATGTTTGAAGAATACAAAACCAAATTTCCCGAGAAGGGTAAAGAATTGCAAAGAAGATTGAATGGTGAGTTACCGGAAGGTTGGGAAAAGCATTTACCGAAGTTTACTCCGGACGACGATGCTCTGGCAACAAGAAAGACATCCCAGCAGGTGCTGACGAACATGGTCCAAGTTTTGCCTGAATTGATCGGTGGTTCTGCCGATTTGACACCTTCGAATCTGACAAGGTGGGAAGGCGCGGTAGATTTCCAACCTCCCATTACCCAACTAGGTAACTATGCAGGAAGGTACATTAGATACGGTGTGAGGGAACACGGAATGGGTGCCATTATGAACGGTATCTCTGCCTTTGGTGCAAACTACAAGCCTTACGGTGGTACCTTTTTGAACTTCGTCTCTTATGCTGCAGGAGCCGTTAGGTTAGCCGCCTTGTCTGGTAATCCAGTCATTTGGGTTGCAACACATGACTCTATCGGGCTTGGTGAGGATGGTCCAACGCACCAACCTATTGAAACTCTGGCTCACTTGAGGGCTATTCCAAACATGCATGTATGGAGACCTGCTGATGGTAACGAAACTTCTGCTGCGTATTATTCTGCTATCAAATCTGGTCGAACACCATCTGTTGTGGCTTTATCACGACAGAATCTTCCTCAATTGGAGCATTCCTCTTTTGAAAAAGCCTTGAAGGGTGGCTATGTGATCCATGACGTGGAGAATCCTGATATTATCCTGGTGTCAACAGGATCAGAAGTCTCCATTTCTATAGATGCAGCCAAAAAATTGTACGATACTAAAAAAATCAAAGCAAGAGTTGTTTCCCTGCCAGACTTTTATACTTTTGACAGGCAAAGTGAAGAATACAGATTCTCTGTTCTACCAGACGGTGTTCCGATCATGTCCTTTGAAGTATTGGCTACTTCAAGCTGGGGTAAGTATGCTCATCAATCGTTCGGACTCGACGAATTTGGTCGTTCAGGCAAGGGGCCTGAAATTTACAAATTGTTCGATTTCACAGCGGACGGTGTTGCGTCAAGGGCTGAAAAGACAATCAATTACTACAAAGGAAAGCAGTTGCTTTCTCCTATGGGAAGAGCTTTCTAA","protein_sequence":"MAQFSDIDKLAVSTLRLLSVDQVESAQSGHPGAPLGLAPVAHVIFKQLRCNPNNEHWINRDRFVLSNGHSCALLYSMLHLLGYDYSIEDLRQFRQVNSRTPGHPEFHSAGVEITSGPLGQGISNAVGMAIAQANFAATYNEDGFPISDSYTFAIVGDGCLQEGVSSETSSLAGHLQLGNLITFYDSNSISIDGKTSYSFDEDVLKRYEAYGWEVMEVDKGDDDMESISSALEKAKLSKDKPTIIKVTTTIGFGSLQQGTAGVHGSALKADDVKQLKKRWGFDPNKSFVVPQEVYDYYKKTVVEPGQKLNEEWDRMFEEYKTKFPEKGKELQRRLNGELPEGWEKHLPKFTPDDDALATRKTSQQVLTNMVQVLPELIGGSADLTPSNLTRWEGAVDFQPPITQLGNYAGRYIRYGVREHGMGAIMNGISAFGANYKPYGGTFLNFVSYAAGAVRLAALSGNPVIWVATHDSIGLGEDGPTHQPIETLAHLRAIPNMHVWRPADGNETSAAYYSAIKSGRTPSVVALSRQNLPQLEHSSFEKALKGGYVIHDVENPDIILVSTGSEVSISIDAAKKLYDTKKIKARVVSLPDFYTFDRQSEEYRFSVLPDGVPIMSFEVLATSSWGKYAHQSFGLDEFGRSGKGPEIYKLFDFTADGVASRAEKTINYYKGKQLLSPMGRAF"},{"created_at":"2011-05-26T17:44:05.000Z","updated_at":"2011-05-27T15:01:02.000Z","name":"Transaldolase NQM1","uniprot_id":"P53228","uniprot_name":"TAL2_YEAST","enzyme":true,"transporter":false,"gene_name":"NQM1","num_residues":333,"molecular_weight":"37253.30078","theoretical_pi":"6.33","general_function":"Involved in catalytic activity","specific_function":"Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway","reactions":[{"id":2480,"direction":"\u003e","locations":"","altext":"Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.","export":false,"pw_reaction_id":null,"source":null},{"id":14090,"direction":"\u003e","locations":null,"altext":null,"export":true,"pw_reaction_id":"PW_R006511","source":"Smpdb"}],"signal_regions":"None","transmembrane_regions":"None","pdb_id":null,"cellular_location":null,"genbank_gene_id":"AY557832","genbank_protein_id":"45269555","gene_card_id":"NQM1","chromosome_location":"chromosome 7","locus":"YGR043C","synonyms":["Non-quiescent mutant protein 1"],"enzyme_classes":["2.2.1.2"],"go_classes":[{"category":"Component","description":" cell part"},{"category":"Component","description":" intracellular part"},{"category":"Component","description":" cytoplasm"},{"category":"Function","description":" catalytic activity"},{"category":"Function","description":" transferase activity"},{"category":"Function","description":" transferase activity, transferring aldehyde or ketonic groups"},{"category":"Function","description":" transaldolase activity"},{"category":"Process","description":" pentose-phosphate shunt"},{"category":"Process","description":" metabolic process"},{"category":"Process","description":" primary metabolic process"},{"category":"Process","description":" carbohydrate metabolic process"},{"category":"Process","description":" small molecule metabolic process"},{"category":"Process","description":" alcohol metabolic process"},{"category":"Process","description":" monosaccharide metabolic process"},{"category":"Process","description":" hexose metabolic process"},{"category":"Process","description":" glucose metabolic process"},{"category":"Process","description":" glucose catabolic process"}],"pfams":[{"name":"Transaldolase","identifier":"PF00923"}],"pathways":[{"name":"Pentose phosphate pathway","kegg_map_id":"00030"},{"name":"xylitol degradation","kegg_map_id":null}],"gene_sequence":"ATGTCAGAACCTTCAGAGAAAAAACAAAAAGTTGCTACCTCATCTTTAGAACAATTAAAAAAGGCCGGGACCCATGTGGTTGCTGATTCGGGTGATTTTGAGGCTATTTCGAAGTATGAACCACAGGATTCAACAACTAACCCTTCTCTGATATTGGCTGCTTCAAAGTTGGAGAAATATGCGAGGTTTATCGACGCTGCCGTTGAATATGGTAGAAAGCATGGCAAAACTGATCATGAGAAAATCGAGAACGCCATGGATAAGATTTTGGTGGAATTCGGCACCCAGATTTTGAAGGTAGTCCCAGGAAGGGTTTCCACTGAAGTAGACGCAAGGTTATCTTTTGATAAGAAGGCGACGGTGAAGAAGGCTCTCCACATCATCAAACTATATAAAGATGCGGGAGTACCTAAAGAAAGAGTCTTGATCAAGATAGCTTCTACGTGGGAGGGTATCCAAGCTGCTAGAGAATTGGAAGTAAAGCATGGTATTCATTGTAATATGACATTACTGTTTTCCTTTACGCAAGCAGTAGCCTGTGCGGAGGCAAATGTCACATTGATCTCCCCATTTGTTGGAAGGATTATGGACTTTTACAAGGCCCTTTCAGGCAAAGACTATACTGCAGAAACTGATCCCGGTGTTCTTTCTGTTAAGAAGATATACAGTTACTATAAGAGGCACGGTTATGCAACTGAGGTAATGGCGGCTTCTTTCAGGAATTTAGATGAATTGAAGGCGTTAGCCGGTATTGATAATATGACTCTCCCACTGAACCTTCTAGAACAGTTATATGAATCAACAGATCCTATTGAAAACAAATTGAATTCTGAGAGTGCTAAGGAAGAAGGCGTCGAAAAAGTCTCTTCTATCAACGACGAGCCTCATTTCAGATATGTTTTAAACGAAGATCAAATGGCTACAGAAAAACTATCAGATGGTATCAGAAAATTCTCCGCAGACATTGAAGCACTGTACAAACTGGTTGAAGAAAAAATGTGA","protein_sequence":"MSEPSEKKQKVATSSLEQLKKAGTHVVADSGDFEAISKYEPQDSTTNPSLILAASKLEKYARFIDAAVEYGRKHGKTDHEKIENAMDKILVEFGTQILKVVPGRVSTEVDARLSFDKKATVKKALHIIKLYKDAGVPKERVLIKIASTWEGIQAARELEVKHGIHCNMTLLFSFTQAVACAEANVTLISPFVGRIMDFYKALSGKDYTAETDPGVLSVKKIYSYYKRHGYATEVMAASFRNLDELKALAGIDNMTLPLNLLEQLYESTDPIENKLNSESAKEEGVEKVSFINDEPHFRYVLNEDQMATEKLSDGIRKFSADIEALYKLVEEKM"},{"created_at":"2011-05-26T17:46:27.000Z","updated_at":"2011-05-27T15:01:02.000Z","name":"Transketolase 1","uniprot_id":"P23254","uniprot_name":"TKT1_YEAST","enzyme":true,"transporter":false,"gene_name":"TKL1","num_residues":680,"molecular_weight":"73805.0","theoretical_pi":"7.01","general_function":"Involved in catalytic activity","specific_function":"Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate","reactions":[{"id":2017,"direction":"\u003c\u003e","locations":"cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":2018,"direction":"\u003c\u003e","locations":"cytoplasm","altext":null,"export":true,"pw_reaction_id":null,"source":null},{"id":2477,"direction":"\u003e","locations":"","altext":"Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 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1"],"enzyme_classes":["2.2.1.1"],"go_classes":[{"category":"Component","description":" Not Available"},{"category":"Function","description":" catalytic activity"},{"category":"Function","description":" transferase activity"},{"category":"Function","description":" transferase activity, transferring aldehyde or ketonic groups"},{"category":"Function","description":" transketolase activity"},{"category":"Process","description":" metabolic process"}],"pfams":[{"name":"Transket_pyr","identifier":"PF02779"},{"name":"Transketolase_C","identifier":"PF02780"},{"name":"Transketolase_N","identifier":"PF00456"}],"pathways":[{"name":"Pentose phosphate pathway","kegg_map_id":"00030"},{"name":"Riboneogenesis","kegg_map_id":null},{"name":"xylitol 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