Inositol phosphate metabolism
| Source | ID | Pathway |
|---|---|---|
| PathWhiz | PW002495 | |
| KEGG | 00562 |  |
Pathway Metabolites
| YMDB ID | Name CAS Number | IUPAC Name | Formula Weight | Structure |
|---|---|---|---|---|
| YMDB00006 | 1D-Myo-inositol 1,4,5,6-tetrakisphosphate 121010-58-0 | {[(1S,2R,3S,4R,5R,6S)-3,4-dihydroxy-2,5,6-tris(phosphonooxy)cyclohexyl]oxy}phosphonic acid | C6H16O18P4 500.0755 |  |
| YMDB00013 | 5-Diphosphoinositol pentakisphosphate 149714-25-0 | {[(1R,2r,3S,4R,5s,6S)-2-{[hydroxy(phosphonooxy)phosphoryl]oxy}-3,4,5,6-tetrakis(phosphonooxy)cyclohexyl]oxy}phosphonic acid | C6H19O27P7 740.0152 |  |
| YMDB00109 | Adenosine triphosphate 56-65-5 | ({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid | C10H16N5O13P3 507.181 |  |
| YMDB00110 | NAD 53-84-9 | 1-[(2R,3R,4S,5R)-5-[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1lambda5-pyridin-1-ylium | C21H28N7O14P2 664.433 |  |
| YMDB00115 | D-Glyceraldehyde 3-phosphate 142-10-9 | (2-hydroxy-3-oxopropoxy)phosphonic acid | C3H7O6P 170.0578 |  |
| YMDB00173 | Myoinositol 87-89-8 | (1R,2R,3r,4S,5S,6s)-cyclohexane-1,2,3,4,5,6-hexol | C6H12O6 180.1559 |  |
| YMDB00230 | 1-Phosphatidyl-D-myo-inositol | [2,3-bis(formyloxy)propoxy]({[(2R,3S,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy})phosphinic acid | C11H19O13P 390.2345 |  |
| YMDB00291 | Inositol 1,4,5-trisphosphate 88269-39-0 | {[(1R,2S,3R,4R,5S,6R)-2,3,5-trihydroxy-4,6-bis(phosphonooxy)cyclohexyl]oxy}phosphonic acid | C6H15O15P3 420.0956 |  |
| YMDB00312 | Acetyl-CoA 72-89-9 | {[(2R,3S,4R,5R)-2-({[({[(3R)-3-[(2-{[2-(acetylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]-3-hydroxy-2,2-dimethylpropoxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-5-(6-amino-9H-purin-9-yl)-4-hydroxyoxolan-3-yl]oxy}phosphonic acid | C23H38N7O17P3S 809.571 |  |
| YMDB00322 | Dihydroxyacetone phosphate 57-04-5 | (3-hydroxy-2-oxopropoxy)phosphonic acid | C3H7O6P 170.0578 |  |
| YMDB00500 | Myo-Inositol hexakisphosphate 83-86-3 | {[2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl]oxy}phosphonic acid | C6H18O24P6 660.0353 |  |
| YMDB00535 | (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid 20298-95-7 | (1R,2S)-1-hydroxy-1-methylpropane-1,2,3-tricarboxylic acid | C7H10O7 206.1501 |  |
| YMDB00711 | 1D-Myo-Inositol 1,3,4,5-tetrakisphosphate 102850-29-3 | {[(1S,2S,3S,4S,5R,6S)-2,4-dihydroxy-3,5,6-tris(phosphonooxy)cyclohexyl]oxy}phosphonic acid | C6H16O18P4 500.0755 |  |
| YMDB00714 | 1D-myo-inositol 1-phosphate 15421-51-9 | {[(1R,2S,3R,4R,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphonic acid | C6H13O9P 260.1358 |  |
| YMDB00715 | 1D-myo-inositol 3-phosphate 2831-74-5 | {[(1R,2S,3R,4R,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphonic acid | C6H13O9P 260.1358 |  |
| YMDB00764 | 1D-myo-inositol 4,5-bisphosphate | {[(1R,2S,3R,4S,5S,6R)-2,3,4,5-tetrahydroxy-6-(phosphonooxy)cyclohexyl]oxy}phosphonic acid | C6H14O12P2 340.1157 |  |
| YMDB00792 | Myo-inositol 1-phosphate 573-35-3 | {[(1R,2S,3R,4R,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphonic acid | C6H13O9P 260.1358 |  |
| YMDB00852 | 1D-myo-inositol 1,4-bisphosphate 47055-78-7 | {[(1R,2R,3R,4R,5R,6S)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphonic acid | C6H14O12P2 340.1157 |  |
| YMDB00862 | hydron 12408-02-5 | hydron | H 1.00794 |  |
| YMDB00890 | water 7732-18-5 | water | H2O 18.0153 |  |
| YMDB00907 | phosphate 14265-44-2 | phosphoric acid | O4P 94.9714 |  |
| YMDB00914 | ADP 58-64-0 | [({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acid | C10H15N5O10P2 427.2011 |  |
| YMDB00946 | Inositol 1,3,4,5,6-pentakisphosphate 20298-95-7 | {[(1R,2S,3r,4R,5S,6r)-3-hydroxy-2,4,5,6-tetrakis(phosphonooxy)cyclohexyl]oxy}phosphonic acid | C6H17O21P5 580.0554 |  |
| YMDB00947 | Glucose 6-phosphate 56-73-5 | {[(2R,3S,4S,5R)-3,4,5,6-tetrahydroxyoxan-2-yl]methoxy}phosphonic acid | C6H13O9P 260.1358 |  |
| YMDB01520 | Magnesium 7439-95-4 | magnesium(2+) ion | Mg 24.305 |  |
| YMDB16241 | 1-Diphosinositol pentakisphosphate | {[(1S,2S,3R,4S,5R,6R)-3-{[hydroxy(phosphonooxy)phosphoryl]oxy}-2,4,5,6-tetrakis(phosphonooxy)cyclohexyl]oxy}phosphonic acid | C6H19O27P7 740.0152 |  |
| YMDB16333 | 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate | hydrogen {[2,3,4,5,6-pentakis(phosphonatooxy)cyclohexyl phosphonato]oxy}phosphonate | C6H7O27P7 727.918 |  |
| YMDB16334 | 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate | {[(1S,2R,3R,4R,5R,6R)-3-{[hydroxy(phosphonatooxy)phosphoryl]oxy}-2,4,5,6-tetrakis(phosphonatooxy)cyclohexyl phosphonato]oxy}phosphonate | C6H7O30P8 806.889 |  |
| YMDB16335 | 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate | {[(1R,2S,3S,4S,5S,6S)-3-{[hydroxy(phosphonatooxy)phosphoryl]oxy}-2,4,5,6-tetrakis(phosphonatooxy)cyclohexyl phosphonato]oxy}phosphonate | C6H7O30P8 806.889 |  |
Pathway Proteins
| Uniprot ID | Gene Name Locus | Name | Type | Metabolites |
|---|---|---|---|---|
| P07250 | ARG82 YDR173C | Inositol polyphosphate multikinase | Enzyme |
|
| Q06667 | IPK1 YDR315C | Inositol-pentakisphosphate 2-kinase | Enzyme | |
| P42951 | LSB6 YJL100W | Phosphatidylinositol 4-kinase LSB6 | Enzyme | |
| P37297 | STT4 YLR305C | Phosphatidylinositol 4-kinase STT4 | Enzyme | |
| P22543 | VPS34 YLR240W | Phosphatidylinositol 3-kinase VPS34 | Enzyme | |
| P34756 | FAB1 YFR019W | 1-phosphatidylinositol-3-phosphate 5-kinase FAB1 | Enzyme | |
| P39104 | PIK1 YNL267W | Phosphatidylinositol 4-kinase PIK1 | Enzyme | |
| P38994 | MSS4 YDR208W | Probable phosphatidylinositol-4-phosphate 5-kinase MSS4 | Enzyme | |
| P00942 | TPI1 YDR050C | Triosephosphate isomerase | Enzyme | |
| P53916 | TEP1 YNL128W | Probable phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TEP1 | Enzyme | |
| P06197 | PIS1 YPR113W | CDP-diacylglycerol--inositol 3-phosphatidyltransferase | Enzyme | |
| Q05533 | INM2 YDR287W | Inositol monophosphatase 2 | Enzyme | |
| P32383 | PLC1 YPL268W | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase 1 | Enzyme | |
| Q12271 | INP53 YOR109W | Inositol-1,4,5-trisphosphate 5-phosphatase 3 | Enzyme | |
| P50942 | INP52 YNL106C | Inositol-1,4,5-trisphosphate 5-phosphatase 2 | Enzyme | |
| Q08227 | INP54 YOL065C | Inositol-1,4,5-trisphosphate 5-phosphatase 4 | Enzyme | |
| P40559 | INP51 YIL002C | Inositol-1,4,5-trisphosphate 5-phosphatase 1 | Enzyme | |
| P11986 | INO1 YJL153C | Inositol-3-phosphate synthase | Enzyme | |
| P38710 | INM1 YHR046C | Inositol monophosphatase 1 | Enzyme |