Cardiolipin Biosynthesis CL(10:0/14:0/16:1(9Z)/22:1(9Z))

SourceIDPathway
PathWhizPW004120 ThumbThumb?image type=greyscaleThumb?image type=simple

Pathway Metabolites

YMDB ID Name
CAS Number 		IUPAC Name Formula
Weight 		Structure
YMDB00045Coenzyme A
85-61-0		{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-2,2-dimethyl-3-({2-[(2-sulfanylethyl)carbamoyl]ethyl}carbamoyl)propoxy]phosphoryl}oxy)phosphoryl]oxy}methyl)oxolan-3-yl]oxy}phosphonic acidC21H36N7O16P3S
767.534		Thumb
YMDB00073Glycerol 3-phosphate
17989-41-2		[(2R)-2,3-dihydroxypropoxy]phosphonic acidC3H9O6P
172.0737		Thumb
YMDB00219Pyrophosphate
14000-31-8		(phosphonooxy)phosphonic acidH4O7P2
177.9751		Thumb
YMDB00259LPA(16:0/0:0)[3-(hexadecanoyloxy)-2-hydroxypropoxy]phosphonic acidC19H39O7P
410.4825		Thumb
YMDB00279Cytidine triphosphate
65-47-4		({[({[(2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acidC9H16N3O14P3
483.1563		Thumb
YMDB00301Palmityl-CoA
1763-10-6		{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-[({[({3-[(2-{[2-(hexadecanoylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]-3-hydroxy-2,2-dimethylpropoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-4-hydroxyoxolan-3-yl]oxy}phosphonic acidC37H66N7O17P3S
1005.943		Thumb
YMDB00322Dihydroxyacetone phosphate
57-04-5		(3-hydroxy-2-oxopropoxy)phosphonic acidC3H7O6P
170.0578		Thumb
YMDB00406Cytidine monophosphate
63-37-6		{[(2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acidC9H14N3O8P
323.1965		Thumb
YMDB00426NADPH
53-57-6		{[(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-[({[({[(2R,3S,4R,5R)-5-(3-carbamoyl-1,4-dihydropyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-4-hydroxyoxolan-3-yl]oxy}phosphonic acidC21H30N7O17P3
745.4209		Thumb
YMDB00427NADP
53-59-8		1-[(2R,3R,4S,5R)-5-[({[({[(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1lambda5-pyridin-1-yliumC21H29N7O17P3
744.4129		Thumb
YMDB00469hexadec-2-enoyl-CoA
4460-95-1		{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-({[({[(3R)-3-[(2-{[2-(hexadec-2-enoylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]-3-hydroxy-2,2-dimethylpropoxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-4-hydroxyoxolan-3-yl]oxy}phosphonic acidC37H64N7O17P3S
1003.927		Thumb
YMDB00527palmitoyl-CoA
1763-10-6		{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-({[({[(3R)-3-[(2-{[2-(hexadecanoylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]-3-hydroxy-2,2-dimethylpropoxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-4-hydroxyoxolan-3-yl]oxy}phosphonic acidC37H66N7O17P3S
1005.943		Thumb
YMDB00862hydron
12408-02-5		hydronH
1.00794		Thumb
YMDB00890water
7732-18-5		waterH2O
18.0153		Thumb
YMDB00907phosphate
14265-44-2		phosphoric acidO4P
94.9714		Thumb
YMDB01162PA(16:0/16:1(9Z))[(2R)-2-[(9Z)-hexadec-9-enoyloxy]-3-(hexadecanoyloxy)propoxy]phosphonic acidThumb
YMDB02944CL(10:0/14:0/16:1(9Z)/22:1(9Z))[(2S)-3-({[(2R)-3-(decanoyloxy)-2-(tetradecanoyloxy)propoxy](hydroxy)phosphoryl}oxy)-2-hydroxypropoxy][(2R)-2-[(9Z)-docos-9-enoyloxy]-3-[(9Z)-hexadec-9-enoyloxy]propoxy]phosphinic acidC71H134O17P2
1321.784		Thumb
YMDB114491-MLCL(0:0/10:0/14:0/16:1(9Z))[(2S)-3-({[(2R)-2-(decanoyloxy)-3-hydroxypropoxy](hydroxy)phosphoryl}oxy)-2-hydroxypropoxy][(2R)-2-[(9Z)-hexadec-9-enoyloxy]-3-(tetradecanoyloxy)propoxy]phosphinic acidC49H94O16P2
1001.223		Thumb
YMDB117712-MLCL(10:0/14:0/16:1(9Z)/0:0)[(2R)-3-(decanoyloxy)-2-(tetradecanoyloxy)propoxy][(2R)-3-({[(2R)-3-[(9Z)-hexadec-9-enoyloxy]-2-hydroxypropoxy](hydroxy)phosphoryl}oxy)-2-hydroxypropoxy]phosphinic acidC49H94O16P2
1001.223		Thumb
YMDB12069CDP-DG(10:0/14:0){[(2R,3R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[(2R)-3-(decanoyloxy)-2-(tetradecanoyloxy)propoxy](hydroxy)phosphoryl}oxy)phosphinic acidC36H65N3O15P2
841.87		Thumb
YMDB12384CDP-DG(16:1(9Z)/22:1(9Z)){[(2R,3R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[(2R)-2-[(9Z)-docos-9-enoyloxy]-3-[(9Z)-hexadec-9-enoyloxy]propoxy](hydroxy)phosphoryl}oxy)phosphinic acidC50H89N3O15P2
1034.216		Thumb
YMDB13414PA(10:0/14:0)[(2R)-3-(decanoyloxy)-2-(tetradecanoyloxy)propoxy]phosphonic acidC27H53O8P
536.687		Thumb
YMDB14372PGP(16:0/16:0)[(2S)-3-({[(2R)-2,3-bis(hexadecanoyloxy)propoxy](hydroxy)phosphoryl}oxy)-2-hydroxypropoxy]phosphonic acidC38H76O13P2
802.961		Thumb
YMDB14941PG(16:0/16:0)[(2R)-2,3-bis(hexadecanoyloxy)propoxy][(2S)-2,3-dihydroxypropoxy]phosphinic acidC38H75O10P
722.982		Thumb
YMDB16273Glycerone phosphatedilithium(1+) ion 1-hydroxy-3-(phosphonatooxy)propan-2-oneC3H5Li2O6P
181.924		Thumb

Pathway Proteins

Uniprot ID Gene Name
Locus 		Name Type Metabolites
P33333SLC1
YDL052C		Probable 1-acyl-sn-glycerol-3-phosphate acyltransferaseEnzyme
P32784GPT1
YBL011W		Glycerol-3-phosphate O-acyltransferase 1Enzyme
P36148GPT2
YKR067W		Glycerol-3-phosphate O-acyltransferase 2Enzyme
Q08548ALE1
YOR175C		Lysophospholipid acyltransferaseEnzyme
P25578PGS1
YCL004W		CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferaseEnzyme
P38221CDS1
YBR029C		Phosphatidate cytidylyltransferaseEnzyme
Q07560CRD1
YDL142C		Cardiolipin synthaseEnzyme
Q12043TGL5
YOR081C		Lipase 5Enzyme
P36165TGL4
YKR089C		Lipase 4Enzyme
P38812GEP4
YHR100C		Phosphatidylglycerophosphatase GEP4, mitochondrialEnzyme
N1NWI7
Taz1p
N1P9W4
Cld1p
O60200MDM35
Mitochondrial distribution and morphology protein 35TransporterNot Available
P18409MDM10
Mitochondrial distribution and morphology protein 10Not Available
P41800MMM1
Maintenance of mitochondrial morphology protein 1Not Available
P53083MDM34
Mitochondrial distribution and morphology protein 34TransporterNot Available
P53230TAM41
Phosphatidate cytidylyltransferase, mitochondrialEnzyme
Q05776UPS1
Protein UPS1, mitochondrialTransporterNot Available
Q06508LOA1
Lysophosphatidic acid:oleoyl-CoA acyltransferase 1Enzyme
Q92328MDM12
Mitochondrial distribution and morphology protein 12Not Available