Maintenance of mitochondrial morphology protein 1 (P41800)

Identification
NameMaintenance of mitochondrial morphology protein 1
Synonyms
  • Mitochondrial outer membrane protein MMM1
  • Yeast mitochondrial escape protein 6
Gene NameMMM1
Enzyme ClassNot Available
Biological Properties
General Functionprotein import into mitochondrial outer membrane
Specific FunctionComponent of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
Cellular LocationNot Available
SMPDB Pathways
Cardiolipin BiosynthesisPW002431 ThumbThumb?image type=greyscaleThumb?image type=simple
Cardiolipin Biosynthesis CL(10:0/10:0/10:0/28:0)PW003484 ThumbThumb?image type=greyscaleThumb?image type=simple
Cardiolipin Biosynthesis CL(10:0/10:0/10:0/30:0)PW003501 ThumbThumb?image type=greyscaleThumb?image type=simple
Cardiolipin Biosynthesis CL(10:0/10:0/12:0/26:0)PW003502 ThumbThumb?image type=greyscaleThumb?image type=simple
Cardiolipin Biosynthesis CL(10:0/10:0/12:0/28:0)PW003503 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
lipid binding
mitochondrion organization
ERMES complex
mitochondrial genome maintenance
mitochondrial outer membrane translocase complex assembly
mitochondrion-ER tethering
phospholipid transport
protein import into mitochondrial outer membrane
mitochondrial outer membrane
integral component of endoplasmic reticulum membrane
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>1281 bp ATGACTGATAGTGAGAATGAATCCACCGAAACGGATTCGTTAATGACGTTTGACGATTAT ATAAGCAAAGAGCTACCTGAACATTTACAGAGACTAATCATGGAGAATTTGAAGGGTTCT ACTACTAATGACTTAAAGCAAACTTCAAACAACTCAGAGTTTAATGTCAGTAAAAACGGG AGCTTCAAAGGTCTCGATGATGCAATTCAAGCTTTGCAAATGCAAAGCGTGTTGCATCCT TCTTCGTTAGGATCGTTAGCAACGTCCTCCAAATTTTCTGGATGGTCGTTTGCTCAAGGG TTTTTTGTAGGACAGCTAAGCATAGTGTTGTTGTTCATCTTTTTCCTAAAGTTCTTTATA TTCAGTGATGAGCCATCTAAAAGTAAGAATCCGAAACCTGCAGCCTCCCGTCACAGATCA AAATTTAAAGAATATCCCTTTATATCTCGCGAATTCCTGACTTCTCTTGTTAGGAAGGGT GCTAAACAACACTACGAGCTCAATGAAGAGGCAGAAAATGAACATCTTCAAGAACTAGCT CTTATTTTAGAGAAAACCTATTATAATGTCGACGTGCACCCTGCAGAGTCATTGGACTGG TTCAACGTTTTAGTTGCCCAAATAATACAGCAATTCCGCAGTGAGGCTTGGCACAGGGAC AATATCCTTCATTCCTTGAATGATTTTATTGGAAGAAAATCACCCGATCTGCCTGAATAT TTGGATACCATAAAAATAACTGAACTGGATACAGGTGATGATTTCCCCATTTTCTCGAAT TGCAGAATACAATATTCGCCAAATTCAGGAAATAAAAAGCTAGAGGCTAAAATTGATATA GATTTAAATGACCACTTAACTTTAGGAGTAGAAACAAAACTATTACTTAACTATCCAAAG CCTGGTATTGCCGCACTCCCCATAAATCTAGTAGTGTCAATTGTGAGGTTTCAGGCGTGT TTGACCGTATCTTTAACTAATGCAGAGGAGTTTGCTTCTACTTCGAACGGTAGCAGTAGT GAAAACGGTATGGAGGGCAATTCAGGATACTTTTTGATGTTTTCTTTTTCTCCTGAATAT AGAATGGAATTTGAAATCAAGTCGCTAATTGGCTCACGGTCTAAACTTGAAAATATTCCC AAGATCGGCAGTGTCATTGAATACCAAATAAAAAAATGGTTCGTTGAACGATGCGTTGAA CCAAGATTCCAATTTGTCAGGTTACCAAGTATGTGGCCACGTAGTAAAAATACGAGAGAA GAAAAGCCTACAGAGTTATAA
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues426
Protein Molecular Weight48659.585
Protein Theoretical pINot Available
Signalling RegionsNot Available
Transmembrane Regions
  • 101-121
Protein Sequence>Maintenance of mitochondrial morphology protein 1 MTDSENESTETDSLMTFDDYISKELPEHLQRLIMENLKGSTTNDLKQTSNNSEFNVSKNG SFKGLDDAIQALQMQSVLHPSSLGSLATSSKFSGWSFAQGFFVGQLSIVLLFIFFLKFFI FSDEPSKSKNPKPAASRHRSKFKEYPFISREFLTSLVRKGAKQHYELNEEAENEHLQELA LILEKTYYNVDVHPAESLDWFNVLVAQIIQQFRSEAWHRDNILHSLNDFIGRKSPDLPEY LDTIKITELDTGDDFPIFSNCRIQYSPNSGNKKLEAKIDIDLNDHLTLGVETKLLLNYPK PGIAALPINLVVSIVRFQACLTVSLTNAEEFASTSNGSSSENGMEGNSGYFLMFSFSPEY RMEFEIKSLIGSRSKLENIPKIGSVIEYQIKKWFVERCVEPRFQFVRLPSMWPRSKNTRE EKPTEL
References
External Links
ResourceLink
Saccharomyces Genome Database MMM1
Uniprot IDP41800
Uniprot NameMMM1
General ReferenceNot Available