Identification |
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Name | Mitochondrial distribution and morphology protein 34 |
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Synonyms | - Mitochondrial outer membrane protein MMM2
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Gene Name | MDM34 |
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Enzyme Class | Not Available |
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Biological Properties |
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General Function | phospholipid transport |
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Specific Function | Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. |
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Cellular Location | Not Available |
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SMPDB Pathways | Cardiolipin Biosynthesis | PW002431 | | Cardiolipin Biosynthesis CL(10:0/10:0/10:0/28:0) | PW003484 | | Cardiolipin Biosynthesis CL(10:0/10:0/10:0/30:0) | PW003501 | | Cardiolipin Biosynthesis CL(10:0/10:0/12:0/26:0) | PW003502 | | Cardiolipin Biosynthesis CL(10:0/10:0/12:0/28:0) | PW003503 | |
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KEGG Pathways | Not Available |
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SMPDB Reactions | Not Available |
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KEGG Reactions | Not Available |
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Metabolites | |
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GO Classification | Function |
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mitochondrion organization | ERMES complex | integral component of mitochondrial outer membrane | mitochondrial genome maintenance | mitochondrion-ER tethering | phospholipid transport | mitochondrial outer membrane |
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Gene Properties |
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Chromosome Location | Not Available |
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Locus | |
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Gene Sequence | >1380 bp
ATGTCATTTAGATTCAACGAAGCTGTGTTTGGTGATAACTCTTTCAATGAACGAATACGG
GAAAAGTTATCTACGGCTTTGAACTCACCGTCTAAAAAGAAATTAGATATCTTGAAAAGC
GGAATTAAGGTACAGAAGGTGGATTTTCCTACAATACCACAGCTAGAAATTCTGGACCTA
GACATTATCACGCAGCCCAAGTCTCTGGCCAAGGGGATTTGCAAGATTTCATGTAAGGAT
GCTATGTTGCGGATACAGACAGTCATAGAGTCGAATCTTTTATTGATTAACGAACAGGAT
ACACCCAGCTTTACCATGCCCCAGCTCATCAATAATGGATCGTTCACAATTCCTATAACT
ATGACGTTCAGTTCCATCGAGCTAGAAGCCATCACGAATATTTTTGTAAAGAACCCTGGA
ATTGGGATATCCTTTAATGACGTTGATTTGGATTTTAAGTTTGATTGTTCTGTAAAAATT
CTCCAAAGCACCATTGAGAGAAGGCTAAAAGAGTCCATGCATGTAGTGTTCAAGGATGTT
CTTCCTTCTTTGATCTTCAACACGTCACAGAACTGGTTCACCAATCGCGGCGAGAGCACC
AGTACCATCCCTGGTAAAAGAGAGCATCATCATCAACAAACTACAATGTCTAGGAATGTA
ATCTTGGACGGATCAGATTTTCAAGAGCTTTCTCCAATAAACATGCTACGTCTTTCAAGC
ATTGTGTCGTCGAGGTCAACACTGTCACTACATTCCACTGTGATGAATTCTCTTTCCGCT
ATACCTGGTTGCTTGGAAAGACAAAACTTGTACAGATTTATATCAAGGATGCCCTCTTTA
AACAATTACTACTCTTCGCAATCATTTCCACAACCAAAGTCATCAACCGTATCATCAAAA
CAATTGGTAAAGCCATTCTACTGTTCCCACAATCTATTACCTAAAACAGTGTTAGATTCC
AGCCAGTACGATTTGGCTACGATAACCAAGATTCAGTCTCGACTTTTCGATAGGAGTAAC
AGCAACGACGACAATGCCAAACCAAGGAGAAGAAAGATCAAATGCAAAAAGACCCGCACA
CCATCGAACCTACAATCACAAGGAGAACAGGCTGTTGATGATAGTACTGCTATTGAAACA
GTTACGTCCACACCGGTCCAAACACCGATACCCGAGCTTGAAGAACAATCTCCCCCATAT
TTGAAAACAACAGTATCGATAAGGGATAAATACGTTATACCAGAAAAAATATCGCTAAAT
TTGGACTCCAAGAAAGATACATCTAAAAAGAAACCGTTTTACTTCATAGGTTTGAACTCG
CAAGAACCTTCAAATAACTGGAAATGGGGCATGGAGGATAGCCCCCCACCATATCATTAA
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Protein Properties |
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Pfam Domain Function | Not Available |
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Protein Residues | 459 |
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Protein Molecular Weight | 51989.81 |
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Protein Theoretical pI | Not Available |
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Signalling Regions | Not Available |
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Transmembrane Regions | Not Available |
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Protein Sequence | >Mitochondrial distribution and morphology protein 34
MSFRFNEAVFGDNSFNERIREKLSTALNSPSKKKLDILKSGIKVQKVDFPTIPQLEILDL
DIITQPKSLAKGICKISCKDAMLRIQTVIESNLLLINEQDTPSFTMPQLINNGSFTIPIT
MTFSSIELEAITNIFVKNPGIGISFNDVDLDFKFDCSVKILQSTIERRLKESMHVVFKDV
LPSLIFNTSQNWFTNRGESTSTIPGKREHHHQQTTMSRNVILDGSDFQELSPINMLRLSS
IVSSRSTLSLHSTVMNSLSAIPGCLERQNLYRFISRMPSLNNYYSSQSFPQPKSSTVSSK
QLVKPFYCSHNLLPKTVLDSSQYDLATITKIQSRLFDRSNSNDDNAKPRRRKIKCKKTRT
PSNLQSQGEQAVDDSTAIETVTSTPVQTPIPELEEQSPPYLKTTVSIRDKYVIPEKISLN
LDSKKDTSKKKPFYFIGLNSQEPSNNWKWGMEDSPPPYH |
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References |
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External Links | Resource | Link |
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Saccharomyces Genome Database | MDM34 | Uniprot ID | P53083 | Uniprot Name | MDM34 |
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General Reference | Not Available |
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