xylitol degradation

Source	ID	Pathway
PathWhiz	PW002433

Pathway Metabolites

YMDB ID	Name CAS Number	IUPAC Name	Formula Weight
YMDB00109	Adenosine triphosphate 56-65-5	({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid	C₁₀H₁₆N₅O₁₃P₃ 507.181
YMDB00110	NAD 53-84-9	1-[(2R,3R,4S,5R)-5-[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1lambda5-pyridin-1-ylium	C₂₁H₂₈N₇O₁₄P₂ 664.433
YMDB00115	D-Glyceraldehyde 3-phosphate 142-10-9	(2-hydroxy-3-oxopropoxy)phosphonic acid	C₃H₇O₆P 170.0578
YMDB00119	D-Ribose 5-phosphate 3615-55-2	{[(2R,3S,4R)-3,4,5-trihydroxyoxolan-2-yl]methoxy}phosphonic acid	C₅H₁₁O₈P 230.1098
YMDB00143	NADH 58-68-4	[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]({[(2R,3S,4R,5R)-5-(3-carbamoyl-1,4-dihydropyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy})phosphinic acid	C₂₁H₂₉N₇O₁₄P₂ 665.441
YMDB00161	D-Xylulose 551-84-8	(3S,4R)-1,3,4,5-tetrahydroxypentan-2-one	C₅H₁₀O₅ 150.1299
YMDB00196	D-Sedoheptulose 7-phosphate 2646-35-7	{[(2R,3S,4R,5S)-3,4,5,6-tetrahydroxy-6-(hydroxymethyl)oxan-2-yl]methoxy}phosphonic acid	C₇H₁₅O₁₀P 290.1618
YMDB00223	D-Erythrose 4-phosphate 585-18-2	[(2R,3R)-2,3-dihydroxy-4-oxobutoxy]phosphonic acid	C₄H₉O₇P 200.0838
YMDB00362	Xylulose 5-phosphate 4212-65-1	{[(2R,3S)-2,3,5-trihydroxy-4-oxopentyl]oxy}phosphonic acid	C₅H₁₁O₈P 230.1098
YMDB00373	D-Xylitol 87-99-0		C₅H₁₂O₅ 152.1458
YMDB00426	NADPH 53-57-6	{[(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-[({[({[(2R,3S,4R,5R)-5-(3-carbamoyl-1,4-dihydropyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-4-hydroxyoxolan-3-yl]oxy}phosphonic acid	C₂₁H₃₀N₇O₁₇P₃ 745.4209
YMDB00427	NADP 53-59-8	1-[(2R,3R,4S,5R)-5-[({[({[(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1lambda5-pyridin-1-ylium	C₂₁H₂₉N₇O₁₇P₃ 744.4129
YMDB00650	alpha-D-ribose 5-phosphate 4300-28-1	{[(2R,3S,4R,5S)-3,4,5-trihydroxyoxolan-2-yl]methoxy}phosphonic acid	C₅H₁₁O₈P 230.1098
YMDB00752	Sedoheptulose 7-phosphate 2646-35-7	{[(2R,3R,4R,5S)-2,3,4,5,7-pentahydroxy-6-oxoheptyl]oxy}phosphonic acid	C₇H₁₅O₁₀P 290.1618
YMDB00778	Xylitol 87-99-0	(2R,4S)-pentane-1,2,3,4,5-pentol	C₅H₁₂O₅ 152.1458
YMDB00779	aldehydo-D-Xylose 58-86-6	(3R,4S,5R)-oxane-2,3,4,5-tetrol	C₅H₁₀O₅ 150.1299
YMDB00862	hydron 12408-02-5	hydron	H 1.00794
YMDB00914	ADP 58-64-0	[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acid	C₁₀H₁₅N₅O₁₀P₂ 427.2011
YMDB00948	D-ribulose 5-phosphate 4151-19-3	{[(2R,3R)-2,3,5-trihydroxy-4-oxopentyl]oxy}phosphonic acid	C₅H₁₁O₈P 230.1098
YMDB16262	β-D-fructofuranose 6-phosphate	[3,4,5-trihydroxy-5-(hydroxymethyl)oxolan-2-yl]methyl phosphate	C₆H₁₁O₉P 258.12

Pathway Proteins

Uniprot ID	Gene Name Locus	Name	Type	Metabolites
P33315	TKL2 YBR117C	Transketolase 2	Enzyme	Fructose 6-phosphate D-Glyceraldehyde 3-phosphate D-Ribose 5-phosphate D-Sedoheptulose 7-phosphate D-Erythrose 4-phosphate Xylulose 5-phosphate alpha-D-ribose 5-phosphate Sedoheptulose 7-phosphate Beta-D-Fructose 6-phosphate β-D-fructofuranose 6-phosphate
P53228	NQM1 YGR043C	Transaldolase NQM1	Enzyme	Fructose 6-phosphate D-Glyceraldehyde 3-phosphate D-Sedoheptulose 7-phosphate D-Erythrose 4-phosphate Sedoheptulose 7-phosphate β-D-fructofuranose 6-phosphate
P23254	TKL1 YPR074C	Transketolase 1	Enzyme	Fructose 6-phosphate D-Glyceraldehyde 3-phosphate D-Ribose 5-phosphate D-Sedoheptulose 7-phosphate D-Erythrose 4-phosphate Xylulose 5-phosphate alpha-D-ribose 5-phosphate Sedoheptulose 7-phosphate Beta-D-Fructose 6-phosphate β-D-fructofuranose 6-phosphate
P42826	XKS1 YGR194C	Xylulose kinase	Enzyme	Adenosine triphosphate D-Xylulose Xylulose 5-phosphate hydron ADP
Q07993	XYL2 YLR070C	D-xylulose reductase	Enzyme	NAD NADH D-Xylulose D-Xylitol NAD(+) Xylitol hydron
P38715	GRE3 YHR104W	NADPH-dependent aldose reductase GRE3	Enzyme	D-Lactaldehyde Lactaldehyde Pyruvaldehyde Glycerol D-Glucose D-Xylitol NADPH NADP D-glyceraldehyde L-arabinitol D-glucitol Xylitol aldehydo-D-Xylose hydron L-Arabinose
Q12189	RKI1 YOR095C	Ribose-5-phosphate isomerase	Enzyme	D-Ribose 5-phosphate alpha-D-ribose 5-phosphate D-ribulose 5-phosphate
P46969	RPE1 YJL121C	Ribulose-phosphate 3-epimerase	Enzyme	Xylulose 5-phosphate D-ribulose 5-phosphate
P15019	TAL1	Transaldolase	Enzyme	Fructose 6-phosphate D-Glyceraldehyde 3-phosphate D-Sedoheptulose 7-phosphate D-Erythrose 4-phosphate Sedoheptulose 7-phosphate β-D-fructofuranose 6-phosphate