| Identification |
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| Name | D-xylulose reductase |
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| Synonyms | - Xylitol dehydrogenase
- XDH
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| Gene Name | XYL2 |
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| Enzyme Class | |
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| Biological Properties |
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| General Function | Involved in zinc ion binding |
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| Specific Function | Xylitol + NAD(+) = D-xylulose + NADH |
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| Cellular Location | Not Available |
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| SMPDB Pathways | |
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| KEGG Pathways | | Pentose and glucuronate interconversions | ec00040 |  |
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| SMPDB Reactions | |
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| KEGG Reactions | |
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| Metabolites | | YMDB ID | Name | View |
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| YMDB00110 | NAD | Show | | YMDB00143 | NADH | Show | | YMDB00161 | D-Xylulose | Show | | YMDB00373 | D-Xylitol | Show | | YMDB00412 | NAD(+) | Show | | YMDB00778 | Xylitol | Show | | YMDB00862 | hydron | Show |
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| GO Classification | | Component |
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| Not Available | | Function |
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| binding | | ion binding | | cation binding | | metal ion binding | | transition metal ion binding | | oxidoreductase activity | | zinc ion binding | | catalytic activity | | Process |
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| metabolic process | | oxidation reduction |
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| Gene Properties |
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| Chromosome Location | chromosome 12 |
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| Locus | YLR070C |
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| Gene Sequence | >1071 bp
ATGACTGACTTAACTACACAAGAAGCTATTGTTCTAGAGCGACCTGGTAAAATCACCCTA
ACTAATGTCAGCATCCCAAAGATTTCAGATCCTAACGAAGTAATCATCCAGATCAAGGCG
ACAGGAATATGCGGGTCAGATATCCATTACTATACCCATGGAAGAATAGCCAATTACGTG
GTAGAATCACCAATGGTGCTGGGACATGAATCATCAGGAATAGTGGCCCTCATAGGTGAG
AACGTCAAGACACTTAAAGTAGGAGATAGGGTGGCACTTGAGCCCGGAATACCTGACAGG
TTTTCACCGGAGATGAAAGAGGGCAGATACAACCTGGACCCCAATTTAAAATTTGCTGCG
ACACCTCCCTTTGATGGGACCTTGACAAAGTATTATAAGACCATGAAAGATTTCGTCTAT
AAACTTCCTGATGATGTGTCATTCGAGGAAGGAGCACTAATAGAGCCATTATCAGTGGCA
ATCCATGCTAATAAATTAGCAAAGATCAAGTTTGGAGCCCGTTGCGTCGTCTTTGGAGCT
GGGCCCATAGGTTTGCTAGCCGGGAAAGTAGCCAGTGTCTTTGGTGCTGCAGATGTTGTT
TTTGTAGATCTATTAGAAAACAAGCTGGAAACGGCTAGGCAGTTTGGTGCCACCCACATC
GTCAACTCAGGTGATCTCCCACATGGCGTTACTGTAGATAGTGTTATAAAAAAAGCAATC
GGCAAGAAAGGTGCTGACGTTGTGTTTGAATGTTCTGGTGCAGAGCCTTGCGTTCGAGCA
GGCATCGAAGTCTGTAAGGCAGGTGGAACGATCGTTCAAGTTGGAATGGGACAAGAGGAA
ATACAATTTCCCATCTCGATCATTCCAACAAAAGAACTGACATTCCAAGGCTGTTTCCGA
TACTGTCAAGGTGATTATAGTGACTCCATCGAGCTAGTCTCTAGCAGAAAACTCTCGCTT
AAACCATTCATTACACATCGCTATAGCTTTAAGGATGCTGTCGAGGCATTCGAAGAAACA
AGCCACCACCCGTTAAATAATATCAAGACGATCATTGAGGGCCCGGAATGA |
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| Protein Properties |
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| Pfam Domain Function | |
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| Protein Residues | 356 |
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| Protein Molecular Weight | 38600.10156 |
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| Protein Theoretical pI | 6.06 |
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| Signalling Regions | |
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| Transmembrane Regions | |
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| Protein Sequence | >D-xylulose reductase
MTDLTTQEAIVLERPGKITLTNVSIPKISDPNEVIIQIKATGICGSDIHYYTHGRIANYV
VESPMVLGHESSGIVALIGENVKTLKVGDRVALEPGIPDRFSPEMKEGRYNLDPNLKFAA
TPPFDGTLTKYYKTMKDFVYKLPDDVSFEEGALIEPLSVAIHANKLAKIKFGARCVVFGA
GPIGLLAGKVASVFGAADVVFVDLLENKLETARQFGATHIVNSGDLPHGVTVDSVIKKAI
GKKGADVVFECSGAEPCVRAGIEVCKAGGTIVQVGMGQEEIQFPISIIPTKELTFQGCFR
YCQGDYSDSIELVSSRKLSLKPFITHRYSFKDAVEAFEETSHHPLNNIKTIIEGPE |
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| References |
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| External Links | |
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| General Reference | - Johnston, M., Hillier, L., Riles, L., Albermann, K., Andre, B., Ansorge, W., Benes, V., Bruckner, M., Delius, H., Dubois, E., Dusterhoft, A., Entian, K. D., Floeth, M., Goffeau, A., Hebling, U., Heumann, K., Heuss-Neitzel, D., Hilbert, H., Hilger, F., Kleine, K., Kotter, P., Louis, E. J., Messenguy, F., Mewes, H. W., Hoheisel, J. D., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome XII." Nature 387:87-90.9169871
- Richard, P., Toivari, M. H., Penttila, M. (1999). "Evidence that the gene YLR070c of Saccharomyces cerevisiae encodes a xylitol dehydrogenase." FEBS Lett 457:135-138.10486580
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