Citric Acid Cycle

SourceIDPathway
PathWhizPW000952 ThumbThumb?image type=greyscaleThumb?image type=simple

Pathway Metabolites

YMDB ID Name
CAS Number 		IUPAC Name Formula
Weight 		Structure
YMDB00026Isocitric acid
320-77-4		1-hydroxypropane-1,2,3-tricarboxylic acidC6H8O7
192.1235		Thumb
YMDB00045Coenzyme A
85-61-0		{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-2,2-dimethyl-3-({2-[(2-sulfanylethyl)carbamoyl]ethyl}carbamoyl)propoxy]phosphoryl}oxy)phosphoryl]oxy}methyl)oxolan-3-yl]oxy}phosphonic acidC21H36N7O16P3S
767.534		Thumb
YMDB00086Citric acid
77-92-9		2-hydroxypropane-1,2,3-tricarboxylic acidC6H8O7
192.1235		Thumb
YMDB00101Fumaric acid
110-17-8		(2E)-but-2-enedioic acidC4H4O4
116.0722		Thumb
YMDB00109Adenosine triphosphate
56-65-5		({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acidC10H16N5O13P3
507.181		Thumb
YMDB00110NAD
53-84-9		1-[(2R,3R,4S,5R)-5-[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1lambda5-pyridin-1-yliumC21H28N7O14P2
664.433		Thumb
YMDB00143NADH
58-68-4		[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]({[(2R,3S,4R,5R)-5-(3-carbamoyl-1,4-dihydropyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy})phosphinic acidC21H29N7O14P2
665.441		Thumb
YMDB00153Oxoglutaric acid
328-50-7		2-oxopentanedioic acidC5H6O5
146.0981		Thumb
YMDB00175Pyruvic acid
127-17-3		2-oxopropanoic acidC3H4O3
88.0621		Thumb
YMDB00235Oxalacetic acid
328-42-7		2-oxobutanedioic acidC4H4O5
132.0716		Thumb
YMDB00257Guanosine diphosphate
146-91-8		[({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acidC10H15N5O11P2
443.2005		Thumb
YMDB00280(S)-Malic acid
97-67-6		(2S)-2-hydroxybutanedioic acidC4H6O5
134.0874		Thumb
YMDB00282Biotin
58-85-5		5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acidC10H16N2O3S
244.311		Thumb
YMDB00296FAD
146-14-5		{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}[({[(2R,3S,4S)-5-{7,8-dimethyl-2,4-dioxo-2H,3H,4H,10H-benzo[g]pteridin-10-yl}-2,3,4-trihydroxypentyl]oxy}(hydroxy)phosphoryl)oxy]phosphinic acidC27H33N9O15P2
785.5497		Thumb
YMDB00312Acetyl-CoA
72-89-9		{[(2R,3S,4R,5R)-2-({[({[(3R)-3-[(2-{[2-(acetylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]-3-hydroxy-2,2-dimethylpropoxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-5-(6-amino-9H-purin-9-yl)-4-hydroxyoxolan-3-yl]oxy}phosphonic acidC23H38N7O17P3S
809.571		Thumb
YMDB00338Succinic acid
110-15-6		butanedioic acidC4H6O4
118.088		Thumb
YMDB00381Thiamine pyrophosphate
154-87-0		3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-iumC12H19N4O7P2S
425.314		Thumb
YMDB00514Succinyl-CoA
604-98-8		4-[(2-{3-[(2R)-3-[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-2-hydroxy-3-methylbutanamido]propanamido}ethyl)sulfanyl]-4-oxobutanoic acidC25H40N7O19P3S
867.607		Thumb
YMDB00558GTP
86-01-1		({[({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acidC10H16N5O14P3
523.1804		Thumb
YMDB00597FADH2
1910-41-4		{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}[({[(2R,3S,4S)-5-{7,8-dimethyl-2,4-dioxo-1H,2H,3H,4H,5H,10H-benzo[g]pteridin-10-yl}-2,3,4-trihydroxypentyl]oxy}(hydroxy)phosphoryl)oxy]phosphinic acidC27H35N9O15P2
787.5656		Thumb
YMDB00630cis-aconitic acid
585-84-2		(1Z)-prop-1-ene-1,2,3-tricarboxylic acidC6H6O6
174.1082		Thumb
YMDB00697lipoamide
940-69-2		5-(1,2-dithiolan-3-yl)pentanamideC8H15NOS2
205.341		Thumb
YMDB00862hydron
12408-02-5		hydronH
1.00794		Thumb
YMDB00890water
7732-18-5		waterH2O
18.0153		Thumb
YMDB00902ubiquinol
56275-39-9		2,3-dimethoxy-5-methyl-6-[(2E,6E,10E,14E,18E,22E,26E)-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaen-1-yl]benzene-1,4-diolC49H78O4
731.1412		Thumb
YMDB00907phosphate
14265-44-2		phosphoric acidO4P
94.9714		Thumb
YMDB00912Carbon dioxide
124-38-9		methanedioneCO2
44.0095		Thumb
YMDB00914ADP
58-64-0		[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acidC10H15N5O10P2
427.2011		Thumb
YMDB01064(S)-malate(2-)(2S)-2-hydroxybutanedioateC4H4O5
132.0716		Thumb
YMDB01093thiamine(1+) diphosphate(1-)3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(hydrogen phosphonatooxy)(hydroxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-iumC12H18N4O7P2S
424.306		Thumb
YMDB01520Magnesium
7439-95-4		magnesium(2+) ionMg
24.305		Thumb
YMDB01521Manganese
7439-96-5		manganese(2+) ionMn
54.938045		Thumb
YMDB16118Hydrogen carbonatecarbonic acidCHO3
61.0168		Thumb
YMDB16129Coenzyme Q102-[(2E,6E,10E,14E,18E,22E,26Z,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaen-1-yl]-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dioneC59H90O4
863.3435		Thumb
YMDB16248QH(2)2,3-dimethoxy-5-methyl-6-(3-methylbut-2-en-1-yl)benzene-1,4-diolC14H20O4
252.3062		Thumb
YMDB162524Fe-4Stetrakis(lambda1-iron(1+) ion) tetrasulfane tetrasulfanideFe4H12S8
491.96		Thumb

Pathway Proteins

Uniprot ID Gene Name
Locus 		Name Type Metabolites
Q68EW0ogdhl
2-oxoglutarate dehydrogenase-like, mitochondrialNot Available
Q6AZR3sdhd-a
Succinate dehydrogenase [ubiquinone] cytochrome b small subunit A, mitochondrialTransporterNot Available
Q6NTP2ireb2
Iron-responsive element-binding protein 2Not Available
Q801S2sdha-b
Succinate dehydrogenase [ubiquinone] flavoprotein subunit B, mitochondrialEnzymeNot Available