Propanoate metabolism

Source	ID	Pathway
KEGG	00640

Pathway Metabolites

YMDB ID	Name CAS Number	IUPAC Name	Formula Weight	Structure
YMDB00071	2-Ketobutyric acid 600-18-0	2-oxobutanoic acid	C₄H₆O₃ 102.0886
YMDB00094	Methylisocitric acid 20298-95-7	1-hydroxy-1-methylpropane-1,2,3-tricarboxylic acid	C₇H₁₀O₇ 206.1501
YMDB00152	L-Valine 72-18-4	(2S)-2-amino-3-methylbutanoic acid	C₅H₁₁NO₂ 117.1463
YMDB00195	Beta-Alanine 107-95-9	3-aminopropanoic acid	C₃H₇NO₂ 89.0932
YMDB00247	L-Lactic acid 79-33-4	(2R)-2-hydroxypropanoic acid	C₃H₆O₃ 90.0779
YMDB00312	Acetyl-CoA 72-89-9	{[(2R,3S,4R,5R)-2-({[({[(3R)-3-[(2-{[2-(acetylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]-3-hydroxy-2,2-dimethylpropoxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-5-(6-amino-9H-purin-9-yl)-4-hydroxyoxolan-3-yl]oxy}phosphonic acid	C₂₃H₃₈N₇O₁₇P₃S 809.571
YMDB00338	Succinic acid 110-15-6	butanedioic acid	C₄H₆O₄ 118.088
YMDB00380	cis-2-Methylaconitate 6061-93-4	(1Z)-1-methylprop-1-ene-1,2,3-tricarboxylic acid	C₇H₈O₆ 188.1348
YMDB00441	2-hydroxybutyric acid 71-23-8	2-hydroxybutanoic acid	C₄H₈O₃ 104.1045
YMDB00446	propionyl-CoA 317-66-8	{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-2,2-dimethyl-3-[(2-{[2-(propanoylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]propoxy]phosphoryl}oxy)phosphoryl]oxy}methyl)oxolan-3-yl]oxy}phosphonic acid	C₂₄H₄₀N₇O₁₇P₃S 823.597
YMDB00514	Succinyl-CoA 604-98-8	4-[(2-{3-[(2R)-3-[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-2-hydroxy-3-methylbutanamido]propanamido}ethyl)sulfanyl]-4-oxobutanoic acid	C₂₅H₄₀N₇O₁₉P₃S 867.607
YMDB00529	acetoacetyl-CoA 1420-36-6	{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-2,2-dimethyl-3-{[2-({2-[(3-oxobutanoyl)sulfanyl]ethyl}carbamoyl)ethyl]carbamoyl}propoxy]phosphoryl}oxy)phosphoryl]oxy}methyl)oxolan-3-yl]oxy}phosphonic acid	C₂₅H₄₀N₇O₁₈P₃S 851.607
YMDB00533	malonyl-CoA 524-14-1	3-[(2-{3-[(2R)-3-[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-2-hydroxy-3-methylbutanamido]propanamido}ethyl)sulfanyl]-3-oxopropanoic acid	C₂₄H₃₈N₇O₁₉P₃S 853.58
YMDB00535	(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid 20298-95-7	(1R,2S)-1-hydroxy-1-methylpropane-1,2,3-tricarboxylic acid	C₇H₁₀O₇ 206.1501
YMDB00857	propionic acid 79-09-4	propanoic acid	C₃H₆O₂ 74.0785
YMDB01003	(S)-Lactate 79-33-4		C₃H₅O₃ 89.07
YMDB01011	2-oxobutanoate 600-18-0		C₄H₅O₃ 101.0807
YMDB01377	2-Propyn-1-ol 107-19-7	prop-2-yn-1-ol	C₃H₄O 56.0633

Pathway Proteins

Uniprot ID	Gene Name Locus	Name	Type	Metabolites
P46367	ALD4 YOR374W	Potassium-activated aldehyde dehydrogenase, mitochondrial	Enzyme	Acetaldehyde Coenzyme A Acetic acid NAD NADH Acetyl-CoA gamma-Aminobutyric acid Indoleacetaldehyde NAD(+) NADPH NADP indole-3-acetate 4-aminobutanal hydron water
P54115	ALD6 YPL061W	Magnesium-activated aldehyde dehydrogenase, cytosolic	Enzyme	Acetaldehyde Coenzyme A Acetic acid NAD NADH Acetyl-CoA Indoleacetaldehyde NADPH NADP indole-3-acetate hydron water
P53598	LSC1 YOR142W	Succinyl-CoA ligase [ADP-forming] subunit alpha, mitochondrial	Enzyme	Coenzyme A Adenosine triphosphate Guanosine diphosphate Succinic acid Succinyl-CoA GTP itaconic acid itaconyl-CoA phosphate ADP
P41338	ERG10 YPL028W	Acetyl-CoA acetyltransferase	Enzyme	Coenzyme A Acetyl-CoA acetoacetyl-CoA
P28817	EHD3 YDR036C	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial	Enzyme	Coenzyme A (S)-3-Hydroxyisobutyryl-CoA (2E)-Dodecenoyl-CoA (S)-3-Hydroxyisobutyric acid (S)-3-hydroxydecanoyl-CoA (S)-3-hydroxylauroyl-CoA (S)-3-hydroxypalmitoyl-CoA hexadec-2-enoyl-CoA (S)-3-hydroxytetradecanoyl-CoA water 3-Hydroxybutyryl-CoA Crotonoyl-CoA (S)-Hydroxyoctanoyl-CoA (S)-Hydroxyhexanoyl-CoA trans-2-Hexenoyl-CoA (2E)-Tetradecenoyl-CoA (2E)-Decenoyl-CoA (2E)-Octenoyl-CoA
Q01574	ACS1 YAL054C	Acetyl-coenzyme A synthetase 1	Enzyme	Coenzyme A Acetic acid Adenosine monophosphate Adenosine triphosphate Pyrophosphate Acetyl-CoA propionyl-CoA propionic acid Acetyl adenylate
P52910	ACS2 YLR153C	Acetyl-coenzyme A synthetase 2	Enzyme	Coenzyme A Acetic acid Adenosine monophosphate Adenosine triphosphate Pyrophosphate Acetyl-CoA propionyl-CoA propionic acid Acetyl adenylate
P53312	LSC2 YGR244C	Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial	Enzyme	Coenzyme A Adenosine triphosphate Guanosine diphosphate Succinic acid Succinyl-CoA GTP itaconic acid itaconyl-CoA phosphate ADP
Q12031	ICL2 YPR006C	Mitochondrial 2-methylisocitrate lyase	Enzyme	Methylisocitric acid Pyruvic acid Succinic acid (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid
P32874	HFA1 YMR207C	Acetyl-CoA carboxylase, mitochondrial	Enzyme	Adenosine triphosphate Acetyl-CoA Carbonic acid malonyl-CoA hydron phosphate Carbon dioxide ADP
Q00955	FAS3 YNR016C	Acetyl-CoA carboxylase	Enzyme	Adenosine triphosphate Pyruvic acid Pyrophosphate Oxalacetic acid Acetyl-CoA Carbonic acid malonyl-CoA hydron phosphate Carbon dioxide ADP Hydrogen carbonate
P22281	ALD1	Aldehyde dehydrogenase 1, mitochondrial	Enzyme	NAD NADH
P17649	UGA1 YGR019W	4-aminobutyrate aminotransferase	Enzyme	Oxoglutaric acid Succinic acid semialdehyde L-Glutamic acid gamma-Aminobutyric acid 4-(Glutamylamino) butanoate
Q12428	PDH1 YPR002W	Probable 2-methylcitrate dehydratase	Enzyme	cis-2-Methylaconitate (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid (2S,3S)-2-Methylcitric acid