Methylene-fatty-acyl-phospholipid synthase (P05375)

Identification

Name

Methylene-fatty-acyl-phospholipid synthase

Synonyms

Overproducer of inositol protein 3
Unsaturated phospholipid methyltransferase

Gene Name

OPI3

Enzyme Class

2.1.1.16

Biological Properties

General Function

Involved in N-methyltransferase activity

Specific Function

S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid methylene fatty acid

Cellular Location

Membrane; Multi-pass membrane protein (Potential)

SMPDB Pathways

Phosphatidylcholine biosynthesis PC(14:1(9Z)/20:1(11Z))	PW002898
Phosphatidylcholine biosynthesis PC(14:1(9Z)/20:1(13Z))	PW002897
Phosphatidylcholine biosynthesis PC(14:1(9Z)/22:0)	PW002954
Phosphatidylcholine biosynthesis PC(14:1(9Z)/22:1(11Z))	PW002934
Phosphatidylcholine biosynthesis PC(14:1(9Z)/22:1(9Z))	PW002933

KEGG Pathways

Not Available

SMPDB Reactions

PE-NMe(16:1(9Z)/18:1(11Z)) + S-Adenosyl-L-methionine → PE-NMe2(16:1(9Z)/18:1(11Z)) + S-Adenosylhomocysteine + hydron

PE-NMe2(16:1(9Z)/18:1(11Z)) + S-Adenosyl-L-methionine → S-Adenosylhomocysteine + hydron + PC(16:1(9Z)/18:1(11Z))

PE-NMe(16:1(11Z)/18:1(9Z)) + S-Adenosyl-L-methionine → PE-NMe2(16:1(11Z)/18:1(9Z)) + S-Adenosylhomocysteine + hydron

PE-NMe2(16:1(11Z)/18:1(9Z)) + S-Adenosyl-L-methionine → S-Adenosylhomocysteine + hydron + PC(16:1(11Z)/18:1(9Z))

PE-NMe(16:1(11Z)/18:1(11Z)) + S-Adenosyl-L-methionine → PE-NMe2(16:1(11Z)/18:1(11Z)) + S-Adenosylhomocysteine + hydron

KEGG Reactions

PE(14:0/16:1(9Z)) + S-Adenosylmethionine → S-Adenosylhomocysteine + phosphatidyl-N-methylethanolamine + hydron

phosphatidyl-N,N-dimethylethanolamine + S-Adenosylmethionine → phosphatidylcholine + S-Adenosylhomocysteine

phosphatidyl-N-methylethanolamine + S-Adenosylmethionine → phosphatidyl-N,N-dimethylethanolamine + S-Adenosylhomocysteine + hydron

Metabolites

YMDB ID	Name	View
YMDB00198	S-Adenosylhomocysteine	Show
YMDB00297	S-Adenosylmethionine	Show
YMDB00438	S-Adenosyl-L-methionine	Show
YMDB00862	hydron	Show
YMDB01180	PC(16:0/16:0)	Show
YMDB01185	PC(16:1(9Z)/16:1(9Z))	Show
YMDB01188	PC(18:0/18:0)	Show
YMDB01191	PC(18:1(9Z)/18:1(9Z))	Show
YMDB13563	PC(10:0/10:0)	Show
YMDB13570	PC(14:0/14:0)	Show
YMDB13626	PC(16:1(11Z)/16:1(11Z))	Show
YMDB13690	PE-NMe2(10:0/10:0)	Show
YMDB13691	PE-NMe2(10:0/12:0)	Show
YMDB13692	PE-NMe2(10:0/14:0)	Show
YMDB13693	PE-NMe2(10:0/15:0)	Show
YMDB13694	PE-NMe2(10:0/16:0)	Show
YMDB13695	PE-NMe2(12:0/12:0)	Show
YMDB13696	PE-NMe2(12:0/14:0)	Show
YMDB13697	PE-NMe2(12:0/15:0)	Show
YMDB13698	PE-NMe2(14:0/14:0)	Show
YMDB13699	PE-NMe2(12:0/16:0)	Show
YMDB13700	PE-NMe2(14:0/15:0)	Show
YMDB13701	PE-NMe2(10:0/14:1(9Z))	Show
YMDB13702	PE-NMe2(10:0/14:1(11Z))	Show
YMDB13703	PE-NMe2(12:0/14:1(9Z))	Show
YMDB13704	PE-NMe2(12:0/14:1(11Z))	Show
YMDB13705	PE-NMe2(14:0/14:1(9Z))	Show
YMDB13706	PE-NMe2(14:0/14:1(11Z))	Show
YMDB13707	PE-NMe2(14:1(9Z)/15:0)	Show
YMDB13708	PE-NMe2(14:1(11Z)/15:0)	Show
YMDB13709	PE-NMe2(15:0/15:0)	Show
YMDB13710	PE-NMe2(10:0/20:1(13Z))	Show
YMDB13711	PE-NMe2(10:0/20:1(11Z))	Show
YMDB13712	PE-NMe2(10:0/15:1(9Z))	Show
YMDB13713	PE-NMe2(10:0/15:1(11Z))	Show
YMDB13714	PE-NMe2(10:0/16:1(9Z))	Show
YMDB13715	PE-NMe2(10:0/16:1(11Z))	Show
YMDB13716	PE-NMe2(12:0/18:1(9Z))	Show
YMDB13717	PE-NMe2(12:0/18:1(11Z))	Show
YMDB13718	PE-NMe2(12:0/15:1(9Z))	Show
YMDB13719	PE-NMe2(12:0/15:1(11Z))	Show
YMDB13720	PE-NMe2(14:0/16:1(9Z))	Show
YMDB13721	PE-NMe2(14:0/16:1(11Z))	Show
YMDB13722	PE-NMe2(14:0/15:1(9Z))	Show
YMDB13723	PE-NMe2(14:0/15:1(11Z))	Show
YMDB13724	PE-NMe2(14:1(9Z)/16:0)	Show
YMDB13725	PE-NMe2(14:1(11Z)/16:0)	Show
YMDB13726	PE-NMe2(15:0/15:1(9Z))	Show
YMDB13727	PE-NMe2(15:0/15:1(11Z))	Show
YMDB13728	PE-NMe2(12:0/16:1(9Z))	Show
YMDB13729	PE-NMe2(12:0/16:1(11Z))	Show
YMDB13730	PE-NMe2(14:1(9Z)/14:1(9Z))	Show
YMDB13731	PE-NMe2(14:1(9Z)/14:1(11Z))	Show
YMDB13732	PE-NMe2(14:1(11Z)/14:1(9Z))	Show
YMDB13733	PE-NMe2(14:1(11Z)/14:1(11Z))	Show
YMDB13734	PE-NMe2(14:1(9Z)/15:1(9Z))	Show
YMDB13735	PE-NMe2(14:1(9Z)/15:1(11Z))	Show
YMDB13736	PE-NMe2(14:1(11Z)/15:1(9Z))	Show
YMDB13737	PE-NMe2(14:1(11Z)/15:1(11Z))	Show
YMDB13738	PE-NMe2(14:1(9Z)/16:1(9Z))	Show
YMDB13739	PE-NMe2(14:1(9Z)/16:1(11Z))	Show
YMDB13740	PE-NMe2(14:1(11Z)/16:1(9Z))	Show
YMDB13741	PE-NMe2(14:1(11Z)/16:1(11Z))	Show
YMDB13742	PE-NMe2(15:1(9Z)/15:1(9Z))	Show
YMDB13743	PE-NMe2(15:1(9Z)/15:1(11Z))	Show
YMDB13744	PE-NMe2(15:1(11Z)/15:1(9Z))	Show
YMDB13745	PE-NMe2(15:1(11Z)/15:1(11Z))	Show
YMDB13746	PE-NMe2(15:1(9Z)/16:1(9Z))	Show
YMDB13747	PE-NMe2(15:1(9Z)/16:1(11Z))	Show
YMDB13748	PE-NMe2(15:1(11Z)/16:1(9Z))	Show
YMDB13749	PE-NMe2(15:1(11Z)/16:1(11Z))	Show
YMDB13750	PE-NMe2(14:0/16:0)	Show
YMDB13751	PE-NMe2(15:0/16:1(9Z))	Show
YMDB13752	PE-NMe2(15:0/16:1(11Z))	Show
YMDB13753	PE-NMe2(15:1(9Z)/16:0)	Show
YMDB13754	PE-NMe2(15:1(11Z)/16:0)	Show
YMDB13755	PE-NMe2(14:1(9Z)/18:1(9Z))	Show
YMDB13756	PE-NMe2(14:1(9Z)/18:1(11Z))	Show
YMDB13757	PE-NMe2(14:1(11Z)/18:1(9Z))	Show
YMDB13758	PE-NMe2(14:1(11Z)/18:1(11Z))	Show
YMDB13759	PE-NMe2(16:1(9Z)/16:1(9Z))	Show
YMDB13760	PE-NMe2(16:1(9Z)/16:1(11Z))	Show
YMDB13761	PE-NMe2(16:1(11Z)/16:1(9Z))	Show
YMDB13762	PE-NMe2(16:1(11Z)/16:1(11Z))	Show
YMDB13763	PE-NMe2(10:0/18:1(9Z))	Show
YMDB13764	PE-NMe2(10:0/18:1(11Z))	Show
YMDB13765	PE-NMe2(16:0/16:1(9Z))	Show
YMDB13766	PE-NMe2(16:0/16:1(11Z))	Show
YMDB13767	PE-NMe2(10:0/22:1(9Z))	Show
YMDB13768	PE-NMe2(10:0/22:1(11Z))	Show
YMDB13769	PE-NMe2(10:0/18:0)	Show
YMDB13770	PE-NMe2(12:0/20:1(13Z))	Show
YMDB13771	PE-NMe2(12:0/20:1(11Z))	Show
YMDB13772	PE-NMe2(14:0/18:1(9Z))	Show
YMDB13773	PE-NMe2(14:0/18:1(11Z))	Show
YMDB13774	PE-NMe2(14:1(9Z)/18:0)	Show
YMDB13775	PE-NMe2(14:1(11Z)/18:0)	Show
YMDB13776	PE-NMe2(16:0/16:0)	Show
YMDB13777	PE-NMe2(15:1(9Z)/18:1(9Z))	Show
YMDB13778	PE-NMe2(15:1(9Z)/18:1(11Z))	Show
YMDB13779	PE-NMe2(15:1(11Z)/18:1(9Z))	Show
YMDB13780	PE-NMe2(15:1(11Z)/18:1(11Z))	Show
YMDB13781	PE-NMe2(10:0/23:1(9Z))	Show
YMDB13782	PE-NMe2(10:0/23:1(11Z))	Show
YMDB13783	PE-NMe2(12:0/18:0)	Show
YMDB13784	PE-NMe2(15:0/18:1(9Z))	Show
YMDB13785	PE-NMe2(15:0/18:1(11Z))	Show
YMDB13786	PE-NMe2(15:1(9Z)/18:0)	Show
YMDB13787	PE-NMe2(15:1(11Z)/18:0)	Show
YMDB13788	PE-NMe2(14:1(9Z)/20:1(13Z))	Show
YMDB13789	PE-NMe2(14:1(9Z)/20:1(11Z))	Show
YMDB13790	PE-NMe2(14:1(11Z)/20:1(13Z))	Show
YMDB13791	PE-NMe2(14:1(11Z)/20:1(11Z))	Show
YMDB13792	PE-NMe2(16:1(9Z)/18:1(9Z))	Show
YMDB13793	PE-NMe2(16:1(9Z)/18:1(11Z))	Show
YMDB13794	PE-NMe2(16:1(11Z)/18:1(9Z))	Show
YMDB13795	PE-NMe2(16:1(11Z)/18:1(11Z))	Show
YMDB13796	PE-NMe2(10:0/24:1(9Z))	Show
YMDB13797	PE-NMe2(10:0/24:1(11Z))	Show
YMDB13798	PE-NMe2(12:0/22:1(9Z))	Show
YMDB13799	PE-NMe2(12:0/22:1(11Z))	Show
YMDB13800	PE-NMe2(14:0/20:1(13Z))	Show
YMDB13801	PE-NMe2(14:0/20:1(11Z))	Show
YMDB13802	PE-NMe2(14:0/18:0)	Show
YMDB13803	PE-NMe2(14:1(9Z)/20:0)	Show
YMDB13804	PE-NMe2(14:1(11Z)/20:0)	Show
YMDB13805	PE-NMe2(16:0/18:1(9Z))	Show
YMDB13806	PE-NMe2(16:0/18:1(11Z))	Show
YMDB13807	PE-NMe2(16:1(9Z)/18:0)	Show
YMDB13808	PE-NMe2(16:1(11Z)/18:0)	Show
YMDB13809	PE-NMe2(15:1(9Z)/20:1(13Z))	Show
YMDB13810	PE-NMe2(15:1(9Z)/20:1(11Z))	Show
YMDB13811	PE-NMe2(15:1(11Z)/20:1(13Z))	Show
YMDB13812	PE-NMe2(15:1(11Z)/20:1(11Z))	Show
YMDB13813	PE-NMe2(10:0/25:1(9Z))	Show
YMDB13814	PE-NMe2(10:0/25:1(11Z))	Show
YMDB13815	PE-NMe2(10:0/20:0)	Show
YMDB13816	PE-NMe2(12:0/23:1(9Z))	Show
YMDB13817	PE-NMe2(12:0/23:1(11Z))	Show
YMDB13818	PE-NMe2(15:0/20:1(13Z))	Show
YMDB13819	PE-NMe2(15:0/20:1(11Z))	Show
YMDB13820	PE-NMe2(15:0/16:0)	Show
YMDB13821	PE-NMe2(15:1(9Z)/20:0)	Show
YMDB13822	PE-NMe2(15:1(11Z)/20:0)	Show
YMDB13823	PE-NMe2(16:0/18:0)	Show
YMDB13824	PE-NMe2(14:1(9Z)/22:1(9Z))	Show
YMDB13825	PE-NMe2(14:1(9Z)/22:1(11Z))	Show
YMDB13826	PE-NMe2(14:1(11Z)/22:1(9Z))	Show
YMDB13827	PE-NMe2(14:1(11Z)/22:1(11Z))	Show
YMDB13828	PE-NMe2(16:1(9Z)/20:1(13Z))	Show
YMDB13829	PE-NMe2(16:1(9Z)/20:1(11Z))	Show
YMDB13830	PE-NMe2(16:1(11Z)/20:1(13Z))	Show
YMDB13831	PE-NMe2(16:1(11Z)/20:1(11Z))	Show
YMDB13832	PE-NMe2(18:1(9Z)/18:1(9Z))	Show
YMDB13833	PE-NMe2(18:1(9Z)/18:1(11Z))	Show
YMDB13834	PE-NMe2(18:1(11Z)/18:1(9Z))	Show
YMDB13835	PE-NMe2(18:1(11Z)/18:1(11Z))	Show
YMDB13836	PE-NMe2(18:0/18:1(9Z))	Show
YMDB13837	PE-NMe2(18:0/18:1(11Z))	Show
YMDB13838	PE-NMe2(10:0/26:1(9Z))	Show
YMDB13839	PE-NMe2(10:0/26:1(11Z))	Show
YMDB13840	PE-NMe2(12:0/24:1(9Z))	Show
YMDB13841	PE-NMe2(12:0/24:1(11Z))	Show
YMDB13842	PE-NMe2(12:0/20:0)	Show
YMDB13843	PE-NMe2(14:0/22:1(9Z))	Show
YMDB13844	PE-NMe2(14:0/22:1(11Z))	Show
YMDB13845	PE-NMe2(14:1(9Z)/22:0)	Show
YMDB13846	PE-NMe2(14:1(11Z)/22:0)	Show
YMDB13847	PE-NMe2(16:0/20:1(13Z))	Show
YMDB13848	PE-NMe2(16:0/20:1(11Z))	Show
YMDB13849	PE-NMe2(16:1(9Z)/20:0)	Show
YMDB13850	PE-NMe2(16:1(11Z)/20:0)	Show
YMDB13851	PE-NMe2(18:0/18:0)	Show
YMDB13852	PE-NMe(10:0/10:0)	Show
YMDB13853	PE-NMe(10:0/12:0)	Show
YMDB13854	PE-NMe(10:0/14:0)	Show
YMDB13855	PE-NMe(10:0/15:0)	Show
YMDB13856	PE-NMe(10:0/16:0)	Show
YMDB13857	PE-NMe(12:0/12:0)	Show
YMDB13858	PE-NMe(12:0/14:0)	Show
YMDB13859	PE-NMe(12:0/15:0)	Show
YMDB13860	PE-NMe(14:0/14:0)	Show
YMDB13861	PE-NMe(12:0/16:0)	Show
YMDB13862	PE-NMe(14:0/15:0)	Show
YMDB13863	PE-NMe(10:0/14:1(9Z))	Show
YMDB13864	PE-NMe(10:0/14:1(11Z))	Show
YMDB13865	PE-NMe(12:0/14:1(9Z))	Show
YMDB13866	PE-NMe(12:0/14:1(11Z))	Show
YMDB13867	PE-NMe(14:0/14:1(9Z))	Show
YMDB13868	PE-NMe(14:0/14:1(11Z))	Show
YMDB13869	PE-NMe(14:1(9Z)/15:0)	Show
YMDB13870	PE-NMe(14:1(11Z)/15:0)	Show
YMDB13871	PE-NMe(15:0/15:0)	Show
YMDB13872	PE-NMe(10:0/20:1(13Z))	Show
YMDB13873	PE-NMe(10:0/20:1(11Z))	Show
YMDB13874	PE-NMe(10:0/15:1(9Z))	Show
YMDB13875	PE-NMe(10:0/15:1(11Z))	Show
YMDB13876	PE-NMe(10:0/16:1(9Z))	Show
YMDB13877	PE-NMe(10:0/16:1(11Z))	Show
YMDB13878	PE-NMe(12:0/18:1(9Z))	Show
YMDB13879	PE-NMe(12:0/18:1(11Z))	Show
YMDB13880	PE-NMe(12:0/15:1(9Z))	Show
YMDB13881	PE-NMe(12:0/15:1(11Z))	Show
YMDB13882	PE-NMe(14:0/16:1(9Z))	Show
YMDB13883	PE-NMe(14:0/16:1(11Z))	Show
YMDB13884	PE-NMe(14:0/15:1(9Z))	Show
YMDB13885	PE-NMe(14:0/15:1(11Z))	Show
YMDB13886	PE-NMe(14:1(9Z)/16:0)	Show
YMDB13887	PE-NMe(14:1(11Z)/16:0)	Show
YMDB13888	PE-NMe(15:0/15:1(9Z))	Show
YMDB13889	PE-NMe(15:0/15:1(11Z))	Show
YMDB13890	PE-NMe(12:0/16:1(9Z))	Show
YMDB13891	PE-NMe(12:0/16:1(11Z))	Show
YMDB13892	PE-NMe(14:1(9Z)/14:1(9Z))	Show
YMDB13893	PE-NMe(14:1(9Z)/14:1(11Z))	Show
YMDB13894	PE-NMe(14:1(11Z)/14:1(9Z))	Show
YMDB13895	PE-NMe(14:1(11Z)/14:1(11Z))	Show
YMDB13896	PE-NMe(14:1(9Z)/15:1(9Z))	Show
YMDB13897	PE-NMe(14:1(9Z)/15:1(11Z))	Show
YMDB13898	PE-NMe(14:1(11Z)/15:1(9Z))	Show
YMDB13899	PE-NMe(14:1(11Z)/15:1(11Z))	Show
YMDB13900	PE-NMe(14:1(9Z)/16:1(9Z))	Show
YMDB13901	PE-NMe(14:1(9Z)/16:1(11Z))	Show
YMDB13902	PE-NMe(14:1(11Z)/16:1(9Z))	Show
YMDB13903	PE-NMe(14:1(11Z)/16:1(11Z))	Show
YMDB13904	PE-NMe(15:1(9Z)/15:1(9Z))	Show
YMDB13905	PE-NMe(15:1(9Z)/15:1(11Z))	Show
YMDB13906	PE-NMe(15:1(11Z)/15:1(9Z))	Show
YMDB13907	PE-NMe(15:1(11Z)/15:1(11Z))	Show
YMDB13908	PE-NMe(15:1(9Z)/16:1(9Z))	Show
YMDB13909	PE-NMe(15:1(9Z)/16:1(11Z))	Show
YMDB13910	PE-NMe(15:1(11Z)/16:1(9Z))	Show
YMDB13911	PE-NMe(15:1(11Z)/16:1(11Z))	Show
YMDB13912	PE-NMe(14:0/16:0)	Show
YMDB13913	PE-NMe(15:0/16:1(9Z))	Show
YMDB13914	PE-NMe(15:0/16:1(11Z))	Show
YMDB13915	PE-NMe(15:1(9Z)/16:0)	Show
YMDB13916	PE-NMe(15:1(11Z)/16:0)	Show
YMDB13917	PE-NMe(14:1(9Z)/18:1(9Z))	Show
YMDB13918	PE-NMe(14:1(9Z)/18:1(11Z))	Show
YMDB13919	PE-NMe(14:1(11Z)/18:1(9Z))	Show
YMDB13920	PE-NMe(14:1(11Z)/18:1(11Z))	Show
YMDB13921	PE-NMe(16:1(9Z)/16:1(9Z))	Show
YMDB13922	PE-NMe(16:1(9Z)/16:1(11Z))	Show
YMDB13923	PE-NMe(16:1(11Z)/16:1(9Z))	Show
YMDB13924	PE-NMe(16:1(11Z)/16:1(11Z))	Show
YMDB13925	PE-NMe(10:0/18:1(9Z))	Show
YMDB13926	PE-NMe(10:0/18:1(11Z))	Show
YMDB13927	PE-NMe(16:0/16:1(9Z))	Show
YMDB13928	PE-NMe(16:0/16:1(11Z))	Show
YMDB13929	PE-NMe(10:0/22:1(9Z))	Show
YMDB13930	PE-NMe(10:0/22:1(11Z))	Show
YMDB13931	PE-NMe(10:0/18:0)	Show
YMDB13932	PE-NMe(12:0/20:1(13Z))	Show
YMDB13933	PE-NMe(12:0/20:1(11Z))	Show
YMDB13934	PE-NMe(14:0/18:1(9Z))	Show
YMDB13935	PE-NMe(14:0/18:1(11Z))	Show
YMDB13936	PE-NMe(14:1(9Z)/18:0)	Show
YMDB13937	PE-NMe(14:1(11Z)/18:0)	Show
YMDB13938	PE-NMe(16:0/16:0)	Show
YMDB13939	PE-NMe(15:1(9Z)/18:1(9Z))	Show
YMDB13940	PE-NMe(15:1(9Z)/18:1(11Z))	Show
YMDB13941	PE-NMe(15:1(11Z)/18:1(9Z))	Show
YMDB13942	PE-NMe(15:1(11Z)/18:1(11Z))	Show
YMDB13943	PE-NMe(10:0/23:1(9Z))	Show
YMDB13944	PE-NMe(10:0/23:1(11Z))	Show
YMDB13945	PE-NMe(12:0/18:0)	Show
YMDB13946	PE-NMe(15:0/18:1(9Z))	Show
YMDB13947	PE-NMe(15:0/18:1(11Z))	Show
YMDB13948	PE-NMe(15:1(9Z)/18:0)	Show
YMDB13949	PE-NMe(15:1(11Z)/18:0)	Show
YMDB13950	PE-NMe(14:1(9Z)/20:1(13Z))	Show
YMDB13951	PE-NMe(14:1(9Z)/20:1(11Z))	Show
YMDB13952	PE-NMe(14:1(11Z)/20:1(13Z))	Show
YMDB13953	PE-NMe(14:1(11Z)/20:1(11Z))	Show
YMDB13954	PE-NMe(16:1(9Z)/18:1(9Z))	Show
YMDB13955	PE-NMe(16:1(9Z)/18:1(11Z))	Show
YMDB13956	PE-NMe(16:1(11Z)/18:1(9Z))	Show
YMDB13957	PE-NMe(16:1(11Z)/18:1(11Z))	Show
YMDB13958	PE-NMe(10:0/24:1(9Z))	Show
YMDB13959	PE-NMe(10:0/24:1(11Z))	Show
YMDB13960	PE-NMe(12:0/22:1(9Z))	Show
YMDB13961	PE-NMe(12:0/22:1(11Z))	Show
YMDB13962	PE-NMe(14:0/20:1(13Z))	Show
YMDB13963	PE-NMe(14:0/20:1(11Z))	Show
YMDB13964	PE-NMe(14:0/18:0)	Show
YMDB13965	PE-NMe(14:1(9Z)/20:0)	Show
YMDB13966	PE-NMe(14:1(11Z)/20:0)	Show
YMDB13967	PE-NMe(16:0/18:1(9Z))	Show
YMDB13968	PE-NMe(16:0/18:1(11Z))	Show
YMDB13969	PE-NMe(16:1(9Z)/18:0)	Show
YMDB13970	PE-NMe(16:1(11Z)/18:0)	Show
YMDB13971	PE-NMe(15:1(9Z)/20:1(13Z))	Show
YMDB13972	PE-NMe(15:1(9Z)/20:1(11Z))	Show
YMDB13973	PE-NMe(15:1(11Z)/20:1(13Z))	Show
YMDB13974	PE-NMe(15:1(11Z)/20:1(11Z))	Show
YMDB13975	PE-NMe(10:0/25:1(9Z))	Show
YMDB13976	PE-NMe(10:0/25:1(11Z))	Show
YMDB13977	PE-NMe(10:0/20:0)	Show
YMDB13978	PE-NMe(12:0/23:1(9Z))	Show
YMDB13979	PE-NMe(12:0/23:1(11Z))	Show
YMDB13980	PE-NMe(15:0/20:1(13Z))	Show
YMDB13981	PE-NMe(15:0/20:1(11Z))	Show
YMDB13982	PE-NMe(15:0/16:0)	Show
YMDB13983	PE-NMe(15:1(9Z)/20:0)	Show
YMDB13984	PE-NMe(15:1(11Z)/20:0)	Show
YMDB13985	PE-NMe(16:0/18:0)	Show
YMDB13986	PE-NMe(14:1(9Z)/22:1(9Z))	Show
YMDB13987	PE-NMe(14:1(9Z)/22:1(11Z))	Show
YMDB13988	PE-NMe(14:1(11Z)/22:1(9Z))	Show
YMDB13989	PE-NMe(14:1(11Z)/22:1(11Z))	Show
YMDB13990	PE-NMe(16:1(9Z)/20:1(13Z))	Show
YMDB13991	PE-NMe(16:1(9Z)/20:1(11Z))	Show
YMDB13992	PE-NMe(16:1(11Z)/20:1(13Z))	Show
YMDB13993	PE-NMe(16:1(11Z)/20:1(11Z))	Show
YMDB13994	PE-NMe(18:1(9Z)/18:1(9Z))	Show
YMDB13995	PE-NMe(18:1(9Z)/18:1(11Z))	Show
YMDB13996	PE-NMe(18:1(11Z)/18:1(9Z))	Show
YMDB13997	PE-NMe(18:1(11Z)/18:1(11Z))	Show
YMDB13998	PE-NMe(18:0/18:1(9Z))	Show
YMDB13999	PE-NMe(18:0/18:1(11Z))	Show
YMDB14000	PE-NMe(10:0/26:1(9Z))	Show
YMDB14001	PE-NMe(10:0/26:1(11Z))	Show
YMDB14002	PE-NMe(12:0/24:1(9Z))	Show
YMDB14003	PE-NMe(12:0/24:1(11Z))	Show
YMDB14004	PE-NMe(12:0/20:0)	Show
YMDB14005	PE-NMe(14:0/22:1(9Z))	Show
YMDB14006	PE-NMe(14:0/22:1(11Z))	Show
YMDB14007	PE-NMe(14:1(9Z)/22:0)	Show
YMDB14008	PE-NMe(14:1(11Z)/22:0)	Show
YMDB14009	PE-NMe(16:0/20:1(13Z))	Show
YMDB14010	PE-NMe(16:0/20:1(11Z))	Show
YMDB14011	PE-NMe(16:1(9Z)/20:0)	Show
YMDB14012	PE-NMe(16:1(11Z)/20:0)	Show
YMDB14013	PE-NMe(18:0/18:0)	Show
YMDB15897	PC(18:2(9Z,11Z)/18:2(9Z,11Z))	Show
YMDB15898	PC(20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z))	Show
YMDB15899	PE-NMe(18:2(9Z,11Z)/18:2(9Z,11Z))	Show
YMDB15900	PE-NMe(20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z))	Show
YMDB15901	PE-NMe2(18:2(9Z,11Z)/18:2(9Z,11Z))	Show
YMDB15902	PE-NMe2(20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z))	Show

GO Classification

Component
Not Available
Function
catalytic activity
transferase activity
transferase activity, transferring one-carbon groups
methyltransferase activity
N-methyltransferase activity
Process
metabolic process
organophosphate metabolic process
phospholipid metabolic process

Gene Properties

Chromosome Location

chromosome 10

Locus

YJR073C

Gene Sequence

>621 bp ATGAAGGAGTCAGTCCAAGAGATCATCCAGCAACTCATCCACAGTGTCGATTTACAGTCT TCCAAGTTCCAGCTGGCCATTGTGTGCACGATGTTCAATCCTATCTTTTGGAACATCGTT GCAAGAATGGAATACCACAAGCATTCTCTCACCAAGATGTGTGGTGGGGCCAGAAAGGGC TGTTACATGTTGGCGGCGACCATATTTTCGCTAGGTATCGTCAGAGACATGGTGTACGAG TCTGCATTGCGTGAACAGCCTACGTGTTCTCTGATCACGGGCGAGAACTGGACCAAGCTG GGTGTGGCTCTCTTTGGTTTGGGGCAAGTGCTTGTTTTGAGTTCCATGTACAAGCTGGGT ATCACAGGGACGTACTTGGGTGACTATTTCGGCATCCTGATGGATGAGAGAGTCACCGGC TTCCCCTTCAACGTTTCCAACAACCCCATGTACCAGGGTTCCACTTTGTCCTTCTTGGGC ATAGCCCTTTACAAAGGAAAGCCTGCGGGGCTGGTTGTTTCTGCCGTAGTTTACTTCATG TACAAGATCGCTCTTCGTTGGGAAGAACCTTTTACTGCCATGATCTACGCTAACCGTGAT AAGGCCAAAAAGAATATGTAA

Protein Properties

Pfam Domain Function

PEMT (PF04191 )

Protein Residues

206

Protein Molecular Weight

23150.09961

Protein Theoretical pI

9.26

Signalling Regions

None

Transmembrane Regions

25-41
100-117

Protein Sequence

>Methylene-fatty-acyl-phospholipid synthase MKESVQEIIQQLIHSVDLQSSKFQLAIVCTMFNPIFWNIVARMEYHKHSLTKMCGGARKG CYMLAATIFSLGIVRDMVYESALREQPTCSLITGENWTKLGVALFGLGQVLVLSSMYKLG ITGTYLGDYFGILMDERVTGFPFNVSNNPMYQGSTLSFLGIALYKGKPAGLVVSAVVYFM YKIALRWEEPFTAMIYANRDKAKKNM

References

External Links

Resource	Link
Saccharomyces Genome Database	OPI3
Uniprot ID	P05375
Uniprot Name	PEM2_YEAST
GenBank Gene ID	AY557899
Genebank Protein ID	45269689

General Reference

Kodaki, T., Yamashita, S. (1987). "Yeast phosphatidylethanolamine methylation pathway. Cloning and characterization of two distinct methyltransferase genes." J Biol Chem 262:15428-15435.2445736
Huang, M. E., Manus, V., Chuat, J. C., Galibert, F. (1996). "Analysis of a 62 kb DNA sequence of chromosome X reveals 36 open reading frames and a gene cluster with a counterpart on chromosome XI." Yeast 12:869-875.8840504
Galibert, F., Alexandraki, D., Baur, A., Boles, E., Chalwatzis, N., Chuat, J. C., Coster, F., Cziepluch, C., De Haan, M., Domdey, H., Durand, P., Entian, K. D., Gatius, M., Goffeau, A., Grivell, L. A., Hennemann, A., Herbert, C. J., Heumann, K., Hilger, F., Hollenberg, C. P., Huang, M. E., Jacq, C., Jauniaux, J. C., Katsoulou, C., Karpfinger-Hartl, L., et, a. l. .. (1996). "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X." EMBO J 15:2031-2049.8641269
Hu, Y., Rolfs, A., Bhullar, B., Murthy, T. V., Zhu, C., Berger, M. F., Camargo, A. A., Kelley, F., McCarron, S., Jepson, D., Richardson, A., Raphael, J., Moreira, D., Taycher, E., Zuo, D., Mohr, S., Kane, M. F., Williamson, J., Simpson, A., Bulyk, M. L., Harlow, E., Marsischky, G., Kolodner, R. D., LaBaer, J. (2007). "Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Genome Res 17:536-543.17322287
Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106