Biotin metabolism

Source	ID	Pathway
KEGG	00780

Pathway Metabolites

YMDB ID	Name CAS Number	IUPAC Name	Formula Weight
YMDB00075	Dethiobiotin 533-48-2	6-[(4R,5S)-5-methyl-2-oxoimidazolidin-4-yl]hexanoic acid	C₁₀H₁₈N₂O₃ 214.2615
YMDB00102	7,8-diaminononanoic acid 21738-21-6	7,8-diaminononanoic acid	C₉H₂₀N₂O₂ 188.2673
YMDB00282	Biotin 58-85-5	5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid	C₁₀H₁₆N₂O₃S 244.311
YMDB00330	L-Lysine 56-87-1	(2S)-2,6-diaminohexanoic acid	C₆H₁₄N₂O₂ 146.1876
YMDB00525	pimeloyl-CoA 18907-20-5	7-[(2-{3-[(2R)-3-[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-2-hydroxy-3-methylbutanamido]propanamido}ethyl)sulfanyl]-7-oxoheptanoic acid	C₂₈H₄₆N₇O₁₉P₃S 909.687
YMDB00602	Biotinyl-5'-AMP 4130-20-5	({5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazolidin-4-yl]pentanoyl}oxy)({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy})phosphinic acid	C₂₀H₂₈N₇O₉PS 573.517
YMDB00905	8-Amino-7-oxononanoic acid 4707-58-8		C₉H₁₇NO₃ 187.2362
YMDB01018	7,8-diaminononanoate		C₁₆H₃₂O₂ 256.4241
YMDB01052	8-amino-7-oxononanoate		C₉H₁₆NO₃ 186.2282

Uniprot ID	Gene Name Locus	Name	Type	Metabolites
P32451	BIO2 YGR286C	Biotin synthase, mitochondrial	Enzyme	Dethiobiotin Sulfide 5'-Deoxyadenosine Biotin S-Adenosylmethionine L-Methionine S-Adenosyl-L-methionine hydron
P53630	BIO4 YNR057C	Dethiobiotin synthetase	Enzyme	Dethiobiotin 7,8-diaminononanoic acid Adenosine triphosphate hydron phosphate Carbon dioxide ADP Diaminopimelic acid
P48445	BPL1 YDL141W	Biotin--protein ligase	Enzyme	Adenosine monophosphate Adenosine triphosphate Pyrophosphate Biotin Biotinyl-5'-AMP hydron
P50277	BIO3 YNR058W	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	Enzyme	7,8-diaminononanoic acid S-adenosyl-4-methylthio-2-oxobutanoic acid S-Adenosylmethionine S-Adenosyl-L-methionine 8-Amino-7-oxononanoic acid S-adenosyl-4-methylthio-2-oxobutanoate Diaminopimelic acid