tetrahydrofolate biosynthesis
| Source | ID | Pathway |
|---|---|---|
| PathWhiz | PW002417 |
Pathway Metabolites
| YMDB ID | Name CAS Number | IUPAC Name | Formula Weight | Structure |
|---|---|---|---|---|
| YMDB00001 | 5'-Phosphoribosyl-N-formylglycinamide 349-34-8 | {[(2R,3S,4R,5R)-3,4-dihydroxy-5-(2-formamidoacetamido)oxolan-2-yl]methoxy}phosphonic acid | C8H15N2O9P 314.1865 |  |
| YMDB00002 | L-Glutamine 56-85-9 | (2S)-2-amino-4-carbamoylbutanoic acid | C5H10N2O3 146.1445 |  |
| YMDB00080 | N10-Formyl-THF 2800-34-2 | (2S)-2-[(4-{N-[(4-hydroxy-2-imino-1,2,5,6,7,8-hexahydropteridin-6-yl)methyl]formamido}phenyl)formamido]pentanedioic acid | C20H23N7O7 473.4393 |  |
| YMDB00097 | Adenosine monophosphate 61-19-8 | {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid | C10H14N5O7P 347.2212 |  |
| YMDB00109 | Adenosine triphosphate 56-65-5 | ({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid | C10H16N5O13P3 507.181 |  |
| YMDB00139 | Tetrahydrofolic acid 135-16-0 | 2-{[4-({[(6S)-4-hydroxy-2-imino-1,2,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid | C19H23N7O6 445.4292 |  |
| YMDB00148 | Chorismate 55508-12-8 | (3R,4R)-3-[(1-carboxyeth-1-en-1-yl)oxy]-4-hydroxycyclohexa-1,5-diene-1-carboxylic acid | C10H10O6 226.1828 |  |
| YMDB00149 | 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol 3672-03-5 | 2-amino-6-(hydroxymethyl)-3,4,7,8-tetrahydropteridin-4-one | C7H9N5O2 195.1787 |  |
| YMDB00175 | Pyruvic acid 127-17-3 | 2-oxopropanoic acid | C3H4O3 88.0621 |  |
| YMDB00176 | 5,10-Methenyltetrahydrofolic acid 7444-29-3 | C20H21N7O6 455.424 |  | |
| YMDB00219 | Pyrophosphate 14000-31-8 | (phosphonooxy)phosphonic acid | H4O7P2 177.9751 |  |
| YMDB00271 | L-Glutamic acid 56-86-0 | (2S)-2-aminopentanedioic acid | C5H9NO4 147.1293 |  |
| YMDB00293 | 7,8-Dihydropteroic acid 2134-76-1 | 4-{[(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl]amino}benzoic acid | C14H14N6O3 314.2994 |  |
| YMDB00314 | 4-amino-4-deoxychorismic acid | (3R,4R)-4-amino-3-[(1-carboxyeth-1-en-1-yl)oxy]cyclohexa-1,5-diene-1-carboxylic acid | C10H11NO5 225.198 |  |
| YMDB00343 | Glycolaldehyde 141-46-8 | 2-hydroxyacetaldehyde | C2H4O2 60.052 |  |
| YMDB00385 | Formic acid 64-18-6 | formic acid | CH2O2 46.0254 |  |
| YMDB00426 | NADPH 53-57-6 | {[(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-[({[({[(2R,3S,4R,5R)-5-(3-carbamoyl-1,4-dihydropyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-4-hydroxyoxolan-3-yl]oxy}phosphonic acid | C21H30N7O17P3 745.4209 |  |
| YMDB00427 | NADP 53-59-8 | 1-[(2R,3R,4S,5R)-5-[({[({[(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1lambda5-pyridin-1-ylium | C21H29N7O17P3 744.4129 |  |
| YMDB00483 | 5,6,7,8-Tetrahydrofolic acid 135-16-0 | (2S)-2-[(4-{[(2-amino-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid | C19H23N7O6 445.4292 |  |
| YMDB00493 | 4-Aminobenzoic acid 150-13-0 | 4-aminobenzoic acid | C7H7NO2 137.136 |  |
| YMDB00517 | 10-Formyltetrahydrofolic acid 2800-34-2 | (2S)-2-{[4-(N-{[(6R)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}formamido)phenyl]formamido}pentanedioic acid | C20H23N7O7 473.4393 |  |
| YMDB00558 | GTP 86-01-1 | ({[({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid | C10H16N5O14P3 523.1804 |  |
| YMDB00578 | 7,8-dihydroneopterin 3'-triphosphate 20574-65-6 | {[({[(2R,3S)-3-(2-amino-4-oxo-1,4,7,8-tetrahydropteridin-6-yl)-2,3-dihydroxypropoxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}phosphonic acid | C9H16N5O13P3 495.1703 |  |
| YMDB00579 | 7,8-Dihydroneopterin 1218-98-0 | 2-amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]-1,4,7,8-tetrahydropteridin-4-one | C9H13N5O4 255.2306 |  |
| YMDB00668 | 7,8-dihydroneopterin 3'-phosphate | [(2R,3S)-3-(2-amino-4-oxo-1,4,7,8-tetrahydropteridin-6-yl)-2,3-dihydroxypropoxy]phosphonic acid | C9H14N5O7P 335.2105 |  |
| YMDB00759 | N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide 349-34-8 | {[(2R,3S,4R)-3,4-dihydroxy-5-(2-formamidoacetamido)oxolan-2-yl]methoxy}phosphonic acid | C8H15N2O9P 314.1865 |  |
| YMDB00862 | hydron 12408-02-5 | hydron | H 1.00794 |  |
| YMDB00890 | water 7732-18-5 | water | H2O 18.0153 |  |
| YMDB00907 | phosphate 14265-44-2 | phosphoric acid | O4P 94.9714 |  |
| YMDB00914 | ADP 58-64-0 | [({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acid | C10H15N5O10P2 427.2011 |  |
| YMDB16253 | 4-amino-4-deoxychorismate | 2-{[(1R,6R)-6-amino-3-carboxycyclohexa-2,4-dien-1-yl]oxy}prop-2-enoate | C10H10NO5 224.193 |  |
| YMDB16254 | (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate | 6-({[hydroxy(phosphonooxy)phosphoryl]oxy}methyl)-2-imino-1,2,7,8-tetrahydropteridin-4-olate | C7H8N5O8P2 352.1146 |  |
| YMDB16280 | 7,8-dihydrofolate monoglutamate | (4S)-4-carboxy-4-[(4-{[(2-imino-4-oxido-1,2,7,8-tetrahydropteridin-6-yl)methyl]amino}phenyl)formamido]butanoate | C19H19N7O6 441.405 |  |