One Carbon Pool by Folate I

SourceIDPathway
PathWhizPW002468 ThumbThumb?image type=greyscaleThumb?image type=simple

Pathway Metabolites

YMDB ID Name
CAS Number
IUPAC Name Formula
Weight
Structure
YMDB000015'-Phosphoribosyl-N-formylglycinamide
349-34-8
{[(2R,3S,4R,5R)-3,4-dihydroxy-5-(2-formamidoacetamido)oxolan-2-yl]methoxy}phosphonic acidC8H15N2O9P
314.1865
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YMDB00016Glycine
56-40-6
2-aminoacetic acidC2H5NO2
75.0666
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YMDB00079Dihydrofolic acid
4033-27-6
(2S)-2-[(4-{[(2-amino-4-oxo-1,4,7,8-tetrahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acidC19H21N7O6
443.4133
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YMDB00080N10-Formyl-THF
2800-34-2
(2S)-2-[(4-{N-[(4-hydroxy-2-imino-1,2,5,6,7,8-hexahydropteridin-6-yl)methyl]formamido}phenyl)formamido]pentanedioic acidC20H23N7O7
473.4393
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YMDB00091Ammonia
7664-41-7
ammoniaH3N
17.0305
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YMDB00112L-Serine
56-45-1
(2S)-2-amino-3-hydroxypropanoic acidC3H7NO3
105.0926
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YMDB00139Tetrahydrofolic acid
135-16-0
2-{[4-({[(6S)-4-hydroxy-2-imino-1,2,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acidC19H23N7O6
445.4292
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YMDB001625-Thymidylic acid
365-07-1
{[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}phosphonic acidC10H15N2O8P
322.2085
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YMDB001765,10-Methenyltetrahydrofolic acid
7444-29-3
C20H21N7O6
455.424
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YMDB00221dUMP
964-26-1
{[(2R,3S,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}phosphonic acidC9H13N2O8P
308.1819
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YMDB002385-Methyltetrahydrofolic acid
134-35-0
(2R)-2-[(4-{[(2-amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acidC20H25N7O6
459.4558
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YMDB002605,10-Methylene-THF
31690-11-6
2-({4-[(6aR)-1-hydroxy-3-imino-3H,4H,5H,6H,6aH,7H,8H,9H-imidazo[1,5-f]pteridin-8-yl]phenyl}formamido)pentanedioic acidC20H23N7O6
457.4399
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YMDB00298N5-Formyl-THF
58-05-9
2-[(4-{[(2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acidC20H23N7O7
473.4393
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YMDB00318L-Methionine
63-68-3
(2S)-2-amino-4-(methylsulfanyl)butanoic acidC5H11NO2S
149.211
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YMDB00371Homocysteine
454-29-5
2-amino-4-sulfanylbutanoic acidC4H9NO2S
135.185
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YMDB00374Glycineamideribotide
10074-18-7
{[(2R,3S,4R,5R)-5-(2-aminoacetamido)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acidC7H15N2O8P
286.1764
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YMDB00385Formic acid
64-18-6
formic acidCH2O2
46.0254
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YMDB00426NADPH
53-57-6
{[(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-[({[({[(2R,3S,4R,5R)-5-(3-carbamoyl-1,4-dihydropyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-4-hydroxyoxolan-3-yl]oxy}phosphonic acidC21H30N7O17P3
745.4209
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YMDB00427NADP
53-59-8
1-[(2R,3R,4S,5R)-5-[({[({[(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1lambda5-pyridin-1-yliumC21H29N7O17P3
744.4129
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YMDB004835,6,7,8-Tetrahydrofolic acid
135-16-0
(2S)-2-[(4-{[(2-amino-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acidC19H23N7O6
445.4292
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YMDB0051710-Formyltetrahydrofolic acid
2800-34-2
(2S)-2-{[4-(N-{[(6R)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}formamido)phenyl]formamido}pentanedioic acidC20H23N7O7
473.4393
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YMDB00520L-Homocysteine
6027-13-0
(2S)-2-amino-4-sulfanylbutanoic acidC4H9NO2S
135.185
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YMDB005625-Amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide
3031-94-5
{[(2R,3S,4R,5R)-5-(5-amino-4-carbamoyl-1H-imidazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acidC9H15N4O8P
338.2112
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YMDB00759N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide
349-34-8
{[(2R,3S,4R)-3,4-dihydroxy-5-(2-formamidoacetamido)oxolan-2-yl]methoxy}phosphonic acidC8H15N2O9P
314.1865
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YMDB00760N(1)-(5-phospho-D-ribosyl)glycinamide
10074-18-7
{[(2R,3S,4R)-5-(2-aminoacetamido)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acidC7H15N2O8P
286.1764
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YMDB00848(6R)-5,10-methylenetetrahydrofolic acid
3432-99-3
(2S)-2-({4-[(6aR)-3-amino-1-oxo-1H,2H,5H,6H,6aH,7H,8H,9H-imidazolidino[1,5-f]pteridin-8-yl]phenyl}formamido)pentanedioic acidC20H23N7O6
457.4399
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YMDB00862hydron
12408-02-5
hydronH
1.00794
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YMDB00890water
7732-18-5
waterH2O
18.0153
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YMDB01481Acadesine
3031-94-5
{[(2R,3S,4R,5R)-5-(5-amino-4-carbamoyl-1H-imidazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acidC9H15N4O8P
338.2112
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YMDB16112Folic acid(2S)-2-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acidC19H19N7O6
441.3975
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YMDB161505'-phosphoribosyl-a-N-formylglycineamidine({5-[(Z)-(1-amino-2-formamidoethylidene)amino]-3,4-dihydroxyoxolan-2-yl}methoxy)phosphonic acidC8H16N3O8P
313.2017
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YMDB16256FAICAR{[5-(3-carbamoyl-4-formamido-1H-pyrazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acidC10H15N4O9P
366.223
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YMDB162724-Amino-4-deoxy-L-arabinose[({[(2R,3R,4S,5S)-5-amino-3,4-dihydroxyoxan-2-yl]oxy}(hydroxy)phosphoryl)oxy]({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(4-hydroxy-2-oxo-1,2-dihydropyrimidin-1-yl)oxolan-2-yl]methoxy})phosphinic acidC14H23N3O15P2
535.291
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YMDB16275UDP-4-Deoxy-4-formamido-beta-L-arabinoseN-[(3S,4S,5R,6R)-6-({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(4-hydroxy-2-oxo-1,2-dihydropyrimidin-1-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)-4,5-dihydroxyoxan-3-yl]carboximidic acidC15H23N3O16P2
563.3011
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Pathway Proteins

Uniprot ID Gene Name
Locus
Name Type Metabolites
P21264ADE2
YOR128C
Phosphoribosylaminoimidazole carboxylaseEnzyme
P06785TMP1
YOR074C
Thymidylate synthaseEnzyme
P38009ADE17
YMR120C
Bifunctional purine biosynthesis protein ADE17Enzyme