Lysolipid incorporation into Mitochondria PC(16:1(11Z)/16:1(11Z))

Source	ID	Pathway
PathWhiz	PW002794

Pathway Metabolites

YMDB ID	Name CAS Number	IUPAC Name	Formula Weight
YMDB00109	Adenosine triphosphate 56-65-5	({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid	C₁₀H₁₆N₅O₁₃P₃ 507.181
YMDB00198	S-Adenosylhomocysteine 979-92-0	(2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}sulfanyl)butanoic acid	C₁₄H₂₀N₆O₅S 384.411
YMDB00297	S-Adenosylmethionine 29908-03-0	[(3S)-3-amino-3-carboxypropyl]({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl})methylsulfanium	C₁₅H₂₃N₆O₅S 399.445
YMDB00438	S-Adenosyl-L-methionine 29908-03-0	[(3S)-3-amino-3-carboxypropyl]({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl})methylsulfanium	C₁₅H₂₃N₆O₅S 399.445
YMDB00862	hydron 12408-02-5	hydron	H 1.00794
YMDB00890	water 7732-18-5	water	H₂O 18.0153
YMDB00907	phosphate 14265-44-2	phosphoric acid	O₄P 94.9714
YMDB00914	ADP 58-64-0	[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acid	C₁₀H₁₅N₅O₁₀P₂ 427.2011
YMDB01162	PA(16:0/16:1(9Z))	[(2R)-2-[(9Z)-hexadec-9-enoyloxy]-3-(hexadecanoyloxy)propoxy]phosphonic acid
YMDB01175	PC(14:0/0:0)	(2-{[(2R)-2-hydroxy-3-(tetradecanoyloxy)propyl phosphono]oxy}ethyl)trimethylazanium	C₂₂H₄₆NO₇P 467.5769
YMDB01194	PE(14:0/0:0) 19805-23-3	(2-aminoethoxy)[(2R)-2-hydroxy-3-(tetradecanoyloxy)propoxy]phosphinic acid	C₁₉H₄₀NO₇P 425.4972
YMDB13341	Lyso-PI(16:1(11Z)/0:0)	{3-[(11Z)-hexadec-11-enoyloxy]-2-hydroxypropoxy}[(2,3,4,5,6-pentahydroxycyclohexyl)oxy]phosphinic acid	C₂₅H₄₇O₁₂P 570.613
YMDB13350	Lyso-PI(0:0/16:1(11Z))	{2-[(11Z)-hexadec-11-enoyloxy]-3-hydroxypropoxy}[(2,3,4,5,6-pentahydroxycyclohexyl)oxy]phosphinic acid	C₂₅H₄₇O₁₂P 570.613
YMDB13359	Lyso-PS(16:1(11Z)/0:0)	2-azaniumyl-3-({3-[(11Z)-hexadec-11-enoyloxy]-2-hydroxypropyl phosphono}oxy)propanoate	C₂₂H₄₁NO₉P 494.542
YMDB13368	Lyso-PS(0:0/16:1(11Z))	2-azaniumyl-3-({2-[(11Z)-hexadec-11-enoyloxy]-3-hydroxypropyl phosphono}oxy)propanoate	C₂₂H₄₁NO₉P 494.542
YMDB13626	PC(16:1(11Z)/16:1(11Z))	(2-{[(2R)-2,3-bis[(11Z)-hexadec-11-enoyloxy]propyl phosphono]oxy}ethyl)trimethylazanium	C₄₀H₇₆NO₈P 730.021
YMDB13762	PE-NMe2(16:1(11Z)/16:1(11Z))	{2,3-bis[(11Z)-hexadec-11-enoyloxy]propoxy}[2-(dimethylamino)ethoxy]phosphinic acid	C₃₉H₇₄NO₈P 715.994
YMDB13924	PE-NMe(16:1(11Z)/16:1(11Z))	{2,3-bis[(11Z)-hexadec-11-enoyloxy]propoxy}[2-(methylamino)ethoxy]phosphinic acid	C₃₈H₇₂NO₈P 701.967
YMDB14081	PE(16:1(11Z)/16:1(11Z))	(2-aminoethoxy)[(2R)-2,3-bis[(11Z)-hexadec-11-enoyloxy]propoxy]phosphinic acid	C₃₇H₇₀NO₈P 687.94
YMDB15418	PI(16:1(11Z)/16:1(11Z))	[(2R)-2,3-bis[(11Z)-hexadec-11-enoyloxy]propoxy]({[(1s,3R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy})phosphinic acid	C₄₁H₇₅O₁₃P 807.012
YMDB15569	PS(16:1(11Z)/16:1(11Z))	(2S)-2-amino-3-({[(2R)-2,3-bis[(11Z)-hexadec-11-enoyloxy]propoxy](hydroxy)phosphoryl}oxy)propanoic acid	C₃₈H₇₀NO₁₀P 731.949

Pathway Proteins

Uniprot ID	Gene Name Locus	Name	Type	Metabolites
Q12675	DNF2 YDR093W	Probable phospholipid-transporting ATPase DNF2	Transporter	Adenosine triphosphate water phosphate ADP PC(14:0/0:0) PE(14:0/0:0) Lyso-PI(0:0/14:0) Lyso-PS(0:0/14:0)
P32660	DNF1 YER166W	Probable phospholipid-transporting ATPase DNF1	Transporter	Adenosine triphosphate water phosphate ADP PC(14:0/0:0) PE(14:0/0:0) Lyso-PI(0:0/14:0) Lyso-PS(0:0/14:0)
P05374	PEM1 YGR157W	Phosphatidylethanolamine N-methyltransferase	Enzyme	S-Adenosylhomocysteine S-Adenosylmethionine S-Adenosyl-L-methionine hydron PE(12:0/16:0) PE(12:0/16:1(9Z)) PE(14:0/16:1(9Z)) PE(14:1(9Z)/16:0) PE(16:0/16:0) PE(16:0/16:1(9Z)) PE(16:0/18:1(9Z)) PE(16:1(9Z)/16:1(9Z)) PE(16:1(9Z)/18:1(9Z)) PE(18:0/18:1(9Z)) PE(18:1(9Z)/18:1(9Z)) PE-NMe(10:0/10:0) PE-NMe(10:0/12:0) PE-NMe(10:0/14:0) PE-NMe(10:0/15:0) PE-NMe(10:0/16:0)
P05375	OPI3 YJR073C	Methylene-fatty-acyl-phospholipid synthase	Enzyme	S-Adenosylhomocysteine S-Adenosylmethionine S-Adenosyl-L-methionine hydron PC(16:0/16:0) PC(16:1(9Z)/16:1(9Z)) PC(18:0/18:0) PC(18:1(9Z)/18:1(9Z)) PC(10:0/10:0) PC(14:0/14:0) PC(16:1(11Z)/16:1(11Z)) PE-NMe2(10:0/10:0) PE-NMe2(10:0/12:0) PE-NMe2(10:0/14:0) PE-NMe2(10:0/15:0) PE-NMe2(10:0/16:0) PE-NMe2(12:0/12:0) PE-NMe2(12:0/14:0) PE-NMe2(12:0/15:0) PE-NMe2(14:0/14:0)
P42838	LEM3	Alkylphosphocholine resistance protein LEM3		Adenosine triphosphate water phosphate ADP PC(14:0/0:0) PE(14:0/0:0) Lyso-PI(0:0/14:0) Lyso-PS(0:0/14:0)
A0A0D4EFH3		Ale1p		PC(14:0/0:0) PC(16:0/0:0) PC(16:0/16:0) PC(16:1(9Z)/0:0) PC(16:1(9Z)/16:1(9Z)) PC(18:0/0:0) PC(18:0/18:0) PC(18:1(9Z)/0:0) PC(18:1(9Z)/18:1(9Z)) PE(14:0/0:0) PE(16:0/0:0) PE(16:0/16:0) PI(14:0/14:0) LysoPC(20:4(5Z,8Z,11Z,14Z)) Lyso-PI(0:0/14:0) Lyso-PS(0:0/14:0) PC(10:0/10:0) PC(14:0/14:0) PC(16:1(11Z)/16:1(11Z)) PE(14:0/14:0)