Probable phospholipid-transporting ATPase DNF2 (Q12675)
Identification | |||||||||||||||||||||||||||||||||||||||||||||||||
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Name | Probable phospholipid-transporting ATPase DNF2 | ||||||||||||||||||||||||||||||||||||||||||||||||
Synonyms | Not Available | ||||||||||||||||||||||||||||||||||||||||||||||||
Gene Name | DNF2 | ||||||||||||||||||||||||||||||||||||||||||||||||
Enzyme Class | |||||||||||||||||||||||||||||||||||||||||||||||||
Biological Properties | |||||||||||||||||||||||||||||||||||||||||||||||||
General Function | Involved in nucleotide binding | ||||||||||||||||||||||||||||||||||||||||||||||||
Specific Function | This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of phospholipids. Required for protein transport from Golgi to vacuoles | ||||||||||||||||||||||||||||||||||||||||||||||||
Cellular Location | Cell membrane; Multi-pass membrane protein | ||||||||||||||||||||||||||||||||||||||||||||||||
SMPDB Pathways |
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KEGG Pathways | Not Available | ||||||||||||||||||||||||||||||||||||||||||||||||
SMPDB Reactions |
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KEGG Reactions | Not Available | ||||||||||||||||||||||||||||||||||||||||||||||||
Metabolites |
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GO Classification |
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Gene Properties | |||||||||||||||||||||||||||||||||||||||||||||||||
Chromosome Location | chromosome 4 | ||||||||||||||||||||||||||||||||||||||||||||||||
Locus | YDR093W | ||||||||||||||||||||||||||||||||||||||||||||||||
Gene Sequence | >4839 bp ATGTCAAGTCCCTCCAAACCCACTTCTCCCTTCGTGGATGATATTGAGCATGAATCGGGA TCAGCATCTAATGGTCTGTCGTCCATGTCACCATTTGACGATAGTTTTCAATTTGAAAAA CCCAGTAGTGCGCATGGAAATATTGAAGTAGCGAAAACCGGCGGTTCTGTTTTGAAGCGA CAATCTAAGCCAATGAAAGATATTAGCACACCCGATCTCTCAAAAGTTACTTTTGATGGA ATCGATGATTATAGTAACGATAATGATATTAATGATGATGATGAACTCAATGGTAAAAAA ACCGAGATACATGAACACGAAAATGAGGTGGATGATGACCTCCATTCGTTCCAGGCAACA CCTATGCCTAATACTGGAGGCTTTGAGGATGTTGAGTTGGATAACAATGAAGGTAGCAAC AATGATTCCCAGGCAGATCATAAGTTGAAAAGAGTACGTTTTGGTACAAGAAGAAATAAG TCAGGTAGGATAGATATAAATAGGTCAAAAACATTGAAATGGGCCAAGAAGAACTTCCAC AATGCTATTGATGAATTCAGTACAAAAGAAGACAGTCTCGAAAATTCAGCCTTGCAAAAT AGGTCTGATGAGTTGAGAACAGTTTACTATAATTTACCCTTGCCGGAGGACATGCTTGAC GAGGACGGCTTACCGTTGGCAGTTTACCCGCGTAATAAAATCAGGACTACGAAGTATACT CCATTAACATTTTTTCCCAAGAACATTCTTTTCCAATTTCATAATTTTGCCAATATTTAC TTTTTAATACTGTTGATTCTAGGTGCTTTTCAAATATTTGGTGTGACAAATCCAGGTTTT GCATCCGTTCCCCTAATTGTCATCGTAATTATCACTGCTATTAAGGATGGTATCGAAGAT TCCAGAAGGACTGTATTGGATTTAGAAGTTAATAATACAAGAACACATATCTTAAGCGGG GTGAAGAATGAAAATGTTGCTGTTGATAACGTTTCCTTATGGAGGCGTTTCAAGAAAGCG AATACAAGGGCATTGATTAAAATTTTTGAGTATTTTTCAGAAAACCTCACTGCTGCTGGT AGAGAAAAGAAGTTACAGAAAAAAAGGGAAGAATTACGAAGGAAGAGGAACTCGAGAAGC TTTGGGCCACGTGGGTCTCTGGATTCAATTGGTAGTTACAGAATGTCTGCCGACTTTGGT CGTCCCTCTTTGGATTATGAGAACCTGAATCAAACAATGTCACAGGCTAACAGGTATAAC GATGGTGAAAATTTAGTTGATCGAACGCTACAGCCAAACCCTGAATGTAGGTTTGCCAAG GATTACTGGAAAAATGTTAAAGTTGGTGATATTGTTCGTGTTCACAATAACGATGAAATT CCTGCTGATATGATCTTATTATCGACATCAGATGTTGATGGCGCTTGTTATGTGGAAACC AAAAATTTGGATGGTGAAACAAATCTAAAGGTCCGTCAATCATTAAAATGTAGCAAGATT ATTAAGAGTTCAAGGGATATTACCAGGACGAAGTTTTGGGTTGAAAGTGAAGGCCCACAT GCCAACTTGTATTCTTATCAAGGTAATTTCAAATGGCAAGATACACAAAATGGAAACATC AGAAATGAGCCTGTAAATATCAATAACTTATTATTGAGAGGTTGTACCTTGAGAAACACT AAGTGGGCCATGGGTATGGTTATTTTTACTGGTGACGATACCAAGATTATGATAAACGCT GGTGTCACTCCAACCAAAAAATCCAGAATTTCAAGAGAGTTGAATTTTTCTGTGATTTTG AATTTTGTACTATTGTTTATCCTATGTTTCACTGCTGGTATTGTTAACGGTGTTTATTAT AAACAGAAACCTCGATCGAGAGATTATTTTGAATTTGGTACCATTGGAGGTTCTGCCTCA ACTAACGGTTTTGTTTCTTTTTGGGTGGCGGTTATTCTTTATCAGTCATTGGTTCCGATC TCTTTATATATTTCTGTGGAAATTATTAAGACAGCACAGGCTATTTTCATTTACACTGAT GTTTTGTTGTATAATGCCAAGCTAGACTATCCATGTACACCAAAGTCGTGGAACATCTCC GATGATTTGGGTCAAATTGAGTATATTTTTTCAGATAAAACAGGCACCTTGACACAAAAT GTGATGGAATTCAAAAAATGTACTATTAACGGTGTGTCTTATGGACGTGCCTATACGGAG GCACTAGCAGGCCTGAGGAAGAGACAAGGTGTTGATGTCGAATCGGAAGGTCGTCGCGAA AAGGAAGAGATAGCAAAAGATAGGGAAACAATGATCGACGAATTAAGATCAATGAGTGAT AATACACAGTTTTGTCCGGAGGATTTAACTTTTGTATCTAAGGAAATTGTGGAAGACTTG AAAGGATCCAGTGGCGACCATCAACAAAAGTGCTGTGAACACTTTTTGCTGGCGCTCGCA TTATGTCATTCTGTCCTTGTGGAGCCAAATAAAGATGATCCTAAAAAACTGGACATCAAG GCTCAATCACCTGATGAGTCTGCCTTAGTTTCCACCGCCAGACAATTAGGGTACAGTTTC GTTGGTAGTTCAAAAAGTGGATTGATAGTAGAGATCCAGGGTGTTCAAAAGGAGTTCCAA GTTCTGAACGTACTTGAATTCAATTCGTCGAGAAAAAGGATGAGTTGCATTATCAAGATC CCTGGCTCTACACCAAAGGATGAACCTAAAGCACTGTTAATATGTAAAGGTGCGGATTCC GTTATCTATTCAAGATTAGATCGCACTCAAAACGACGCTACTTTGTTGGAAAAGACGGCC CTCCATTTGGAAGAATATGCCACAGAAGGTTTAAGAACATTATGTTTGGCTCAAAGAGAG CTCACGTGGTCCGAGTATGAACGTTGGGTTAAGACTTATGATGTGGCCGCTGCATCCGTT ACTAATAGGGAGGAAGAGTTGGACAAAGTTACTGACGTTATTGAACGTGAGCTTATTTTG CTTGGTGGTACGGCCATTGAGGATCGTTTACAAGATGGTGTTCCTGATTCGATTGCCCTC TTGGCCGAGGCCGGTATTAAGTTATGGGTCCTAACGGGTGATAAAGTGGAAACTGCCATT AACATTGGTTTTTCCTGCAATGTTTTGAACAATGATATGGAATTATTGGTTGTGAAGGCT TCCGGCGAAGATGTAGAAGAATTTGGTAGTGACCCTATTCAAGTGGTTAACAATTTGGTG ACAAAATACTTAAGGGAAAAATTTGGCATGAGTGGATCCGAGGAGGAGTTAAAAGAAGCT AAAAGAGAGCATGGTTTGCCACAGGGAAATTTTGCTGTCATTATCGATGGCGATGCGCTA AAAGTTGCTTTGAATGGTGAAGAAATGAGACGCAAGTTCTTGCTACTGTGTAAGAATTGT AAAGCTGTTTTGTGTTGCAGAGTTTCTCCAGCACAAAAGGCTGCAGTGGTCAAGTTGGTA AAAAAGACCTTAGACGTTATGACCTTGGCCATTGGTGATGGTTCGAATGATGTAGCCATG ATTCAATCGGCGGACGTTGGTGTTGGTATCGCGGGTGAAGAAGGCAGACAAGCTGTCATG TGTTCTGATTATGCCATCGGGCAGTTCAGATATGTGACAAGACTGGTATTGGTGCATGGT AAATGGTGTTATAAGAGACTGGCAGAGATGATCCCACAGTTTTTCTACAAGAACGTTATT TTTACGCTATCCCTGTTCTGGTATGGTATTTACAATAATTTCGATGGGTCGTATTTGTTT GAGTATACGTACTTGACATTCTACAATCTTGCATTCACATCCGTACCTGTTATTTTACTA GCAGTACTCGACCAAGATGTTTCCGACACCGTTTCGATGCTGGTGCCACAGTTGTACCGT GTGGGTATCCTAAGAAAAGAATGGAACCAAACCAAATTTCTTTGGTACATGTTGGATGGT GTATACCAATCTGTGATATGCTTCTTTTTCCCCTATTTGGCGTACCATAAAAACATGGTT GTAACTGAAAATGGCCTTGGACTAGACCACCGTTACTTTGTCGGTGTCTTCGTTACAGCA ATTGCAGTCACTTCATGTAACTTTTACGTCTTCATGGAACAGTATAGATGGGACTGGTTC TGTGGCCTATTCATATGTCTATCACTGGCCGTGTTTTACGGCTGGACGGGTATATGGACA AGCTCGTCGTCAAGTAACGAATTTTACAAGGGTGCGGCGCGTGTATTCGCACAACCTGCC TATTGGGCAGTACTTTTCGTTGGCGTGCTGTTCTGCCTACTGCCAAGATTCACCATTGAC TGTATCAGAAAGATATTCTATCCGAAAGATATAGAGATCGTTAGAGAAATGTGGTTACGC GGTGATTTTGACCTCTACCCACAAGGCTACGACCCTACGGACCCTAGCAGGCCCAGAATA AACGAAATACGTCCCCTTACAGATTTCAAAGAGCCCATTTCACTGGACACTCATTTTGAT GGTGTCAGCCACTCACAAGAGACCATAGTCACAGAGGAAATACCAATGAGTATACTCAAT GGTGAGCAAGGCTCGCGCAAGGGGTACCGTGTCTCTACCACTCTGGAACGCCGTGACCAG CTCAGCCCCGTTACAACAACGAACAACTTGCCTAGAAGATCAATGGCCAGTGCCCGCGGA AATAAGCTCAGAACTTCGCTGGATCGCACAAGAGAAGAGATGCTTGCCAACCACCAACTG GACACAAGATACTCCGTGGAAAGAGCACGTGCCTCGCTGGATCTGCCGGGTATCAATCAT GCAGAGACGCTGCTCAGCCAGCGCAGCAGGGACCGTTAA | ||||||||||||||||||||||||||||||||||||||||||||||||
Protein Properties | |||||||||||||||||||||||||||||||||||||||||||||||||
Pfam Domain Function | |||||||||||||||||||||||||||||||||||||||||||||||||
Protein Residues | 1612 | ||||||||||||||||||||||||||||||||||||||||||||||||
Protein Molecular Weight | 182617.0 | ||||||||||||||||||||||||||||||||||||||||||||||||
Protein Theoretical pI | 6.04 | ||||||||||||||||||||||||||||||||||||||||||||||||
Signalling Regions |
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Transmembrane Regions |
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Protein Sequence | >Probable phospholipid-transporting ATPase DNF2 MSSPSKPTSPFVDDIEHESGSASNGLSSMSPFDDSFQFEKPSSAHGNIEVAKTGGSVLKR QSKPMKDISTPDLSKVTFDGIDDYSNDNDINDDDELNGKKTEIHEHENEVDDDLHSFQAT PMPNTGGFEDVELDNNEGSNNDSQADHKLKRVRFGTRRNKSGRIDINRSKTLKWAKKNFH NAIDEFSTKEDSLENSALQNRSDELRTVYYNLPLPEDMLDEDGLPLAVYPRNKIRTTKYT PLTFFPKNILFQFHNFANIYFLILLILGAFQIFGVTNPGFASVPLIVIVIITAIKDGIED SRRTVLDLEVNNTRTHILSGVKNENVAVDNVSLWRRFKKANTRALIKIFEYFSENLTAAG REKKLQKKREELRRKRNSRSFGPRGSLDSIGSYRMSADFGRPSLDYENLNQTMSQANRYN DGENLVDRTLQPNPECRFAKDYWKNVKVGDIVRVHNNDEIPADMILLSTSDVDGACYVET KNLDGETNLKVRQSLKCSKIIKSSRDITRTKFWVESEGPHANLYSYQGNFKWQDTQNGNI RNEPVNINNLLLRGCTLRNTKWAMGMVIFTGDDTKIMINAGVTPTKKSRISRELNFSVIL NFVLLFILCFTAGIVNGVYYKQKPRSRDYFEFGTIGGSASTNGFVSFWVAVILYQSLVPI SLYISVEIIKTAQAIFIYTDVLLYNAKLDYPCTPKSWNISDDLGQIEYIFSDKTGTLTQN VMEFKKCTINGVSYGRAYTEALAGLRKRQGVDVESEGRREKEEIAKDRETMIDELRSMSD NTQFCPEDLTFVSKEIVEDLKGSSGDHQQKCCEHFLLALALCHSVLVEPNKDDPKKLDIK AQSPDESALVSTARQLGYSFVGSSKSGLIVEIQGVQKEFQVLNVLEFNSSRKRMSCIIKI PGSTPKDEPKALLICKGADSVIYSRLDRTQNDATLLEKTALHLEEYATEGLRTLCLAQRE LTWSEYERWVKTYDVAAASVTNREEELDKVTDVIERELILLGGTAIEDRLQDGVPDSIAL LAEAGIKLWVLTGDKVETAINIGFSCNVLNNDMELLVVKASGEDVEEFGSDPIQVVNNLV TKYLREKFGMSGSEEELKEAKREHGLPQGNFAVIIDGDALKVALNGEEMRRKFLLLCKNC KAVLCCRVSPAQKAAVVKLVKKTLDVMTLAIGDGSNDVAMIQSADVGVGIAGEEGRQAVM CSDYAIGQFRYVTRLVLVHGKWCYKRLAEMIPQFFYKNVIFTLSLFWYGIYNNFDGSYLF EYTYLTFYNLAFTSVPVILLAVLDQDVSDTVSMLVPQLYRVGILRKEWNQTKFLWYMLDG VYQSVICFFFPYLAYHKNMVVTENGLGLDHRYFVGVFVTAIAVTSCNFYVFMEQYRWDWF CGLFICLSLAVFYGWTGIWTSSSSSNEFYKGAARVFAQPAYWAVLFVGVLFCLLPRFTID CIRKIFYPKDIEIVREMWLRGDFDLYPQGYDPTDPSRPRINEIRPLTDFKEPISLDTHFD GVSHSQETIVTEEIPMSILNGEQGSRKGYRVSTTLERRDQLSPVTTTNNLPRRSMASARG NKLRTSLDRTREEMLANHQLDTRYSVERARASLDLPGINHAETLLSQRSRDR | ||||||||||||||||||||||||||||||||||||||||||||||||
References | |||||||||||||||||||||||||||||||||||||||||||||||||
External Links |
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General Reference |
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