Isoleucine degradation

SourceIDPathway
PathWhizPW002491 ThumbThumb?image type=greyscaleThumb?image type=simple

Pathway Metabolites

YMDB ID Name
CAS Number
IUPAC Name Formula
Weight
Structure
YMDB00038L-Isoleucine
73-32-5
(2S,3S)-2-amino-3-methylpentanoic acidC6H13NO2
131.1729
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YMDB00110NAD
53-84-9
1-[(2R,3R,4S,5R)-5-[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1lambda5-pyridin-1-yliumC21H28N7O14P2
664.433
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YMDB00143NADH
58-68-4
[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]({[(2R,3S,4R,5R)-5-(3-carbamoyl-1,4-dihydropyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy})phosphinic acidC21H29N7O14P2
665.441
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YMDB00153Oxoglutaric acid
328-50-7
2-oxopentanedioic acidC5H6O5
146.0981
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YMDB00168(S)-3-methyl-2-oxovaleric acid
1460-34-0
(3S)-3-methyl-2-oxopentanoic acidC6H10O3
130.1418
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YMDB00271L-Glutamic acid
56-86-0
(2S)-2-aminopentanedioic acidC5H9NO4
147.1293
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YMDB004852-Methylbutanal
96-17-3
2-methylbutanalC5H10O
86.1323
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YMDB005672-methylbutan-1-ol
137-32-6
2-methylbutan-1-olC5H12O
88.1482
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YMDB00862hydron
12408-02-5
hydronH
1.00794
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YMDB00912Carbon dioxide
124-38-9
methanedioneCO2
44.0095
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Pathway Proteins

Uniprot ID Gene Name
Locus
Name Type Metabolites
P16467PDC5
YLR134W
Pyruvate decarboxylase isozyme 2Enzyme
P26263PDC6
YGR087C
Pyruvate decarboxylase isozyme 3Enzyme
P06169PDC1
YLR044C
Pyruvate decarboxylase isozyme 1Enzyme
P47176BAT2
YJR148W
Branched-chain-amino-acid aminotransferase, cytosolicEnzyme
P38891BAT1
YHR208W
Branched-chain-amino-acid aminotransferase, mitochondrialEnzyme
P25377ADH7
YCR105W
NADP-dependent alcohol dehydrogenase 7Enzyme
Q04894ADH6
YMR318C
NADP-dependent alcohol dehydrogenase 6Enzyme