Biotin Biosynthesis
Source | ID | Pathway |
---|---|---|
PathWhiz | PW002380 |
Pathway Metabolites
YMDB ID | Name CAS Number | IUPAC Name | Formula Weight | Structure |
---|---|---|---|---|
YMDB00075 | Dethiobiotin 533-48-2 | 6-[(4R,5S)-5-methyl-2-oxoimidazolidin-4-yl]hexanoic acid | C10H18N2O3 214.2615 | |
YMDB00109 | Adenosine triphosphate 56-65-5 | ({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid | C10H16N5O13P3 507.181 | |
YMDB00150 | 5'-Deoxyadenosine 4754-39-6 | (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-methyloxolane-3,4-diol | C10H13N5O3 251.2419 | |
YMDB00250 | S-adenosyl-4-methylthio-2-oxobutanoic acid | {[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}(3-carboxy-3-oxopropyl)methylsulfanium | C15H20N5O6S 398.414 | |
YMDB00282 | Biotin 58-85-5 | 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid | C10H16N2O3S 244.311 | |
YMDB00297 | S-Adenosylmethionine 29908-03-0 | [(3S)-3-amino-3-carboxypropyl]({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl})methylsulfanium | C15H23N6O5S 399.445 | |
YMDB00318 | L-Methionine 63-68-3 | (2S)-2-amino-4-(methylsulfanyl)butanoic acid | C5H11NO2S 149.211 | |
YMDB00438 | S-Adenosyl-L-methionine 29908-03-0 | [(3S)-3-amino-3-carboxypropyl]({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl})methylsulfanium | C15H23N6O5S 399.445 | |
YMDB00862 | hydron 12408-02-5 | hydron | H 1.00794 | |
YMDB00905 | 8-Amino-7-oxononanoic acid 4707-58-8 | C9H17NO3 187.2362 | ||
YMDB00907 | phosphate 14265-44-2 | phosphoric acid | O4P 94.9714 | |
YMDB00912 | Carbon dioxide 124-38-9 | methanedione | CO2 44.0095 | |
YMDB00914 | ADP 58-64-0 | [({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acid | C10H15N5O10P2 427.2011 | |
YMDB16140 | Diaminopimelic acid | (2S,6S)-2,6-diaminoheptanedioic acid | C7H14N2O4 190.1971 |
Pathway Proteins
Uniprot ID | Gene Name Locus | Name | Type | Metabolites |
---|---|---|---|---|
P32451 | BIO2 YGR286C | Biotin synthase, mitochondrial | Enzyme | |
P53630 | BIO4 YNR057C | Dethiobiotin synthetase | Enzyme | |
P50277 | BIO3 YNR058W | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | Enzyme | |
P53744 | BIO5 YNR056C | 7-keto 8-aminopelargonic acid transporter | Transporter |