Showing Reaction 1143

D-Erythrose 4-phosphate + Phosphoenolpyruvic acid + water → phosphate + 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid
Thumb+Thumb+Thumb→Thumb+Thumb

Enzymes

  1. Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited
  2. Phospho-2-dehydro-3-deoxyheptonate aldolase, phenylalanine-inhibited

Cellular Locations

  • mitochondrion
  • cytoplasm

References

  • Mo, M. L., Palsson, B. O., Herrgard, M. J. (2009). "Connecting extracellular metabolomic measurements to intracellular flux states in yeast." BMC Syst Biol 3:37.19321003
  • Teshiba, S., Furter, R., Niederberger, P., Braus, G., Paravicini, G., Hutter, R. (1986). "Cloning of the ARO3 gene of Saccharomyces cerevisiae and its regulation." Mol Gen Genet 205:353-357.2880280
  • Herrgard, M. J., Swainston, N., Dobson, P., Dunn, W. B., Arga, K. Y., Arvas, M., Bluthgen, N., Borger, S., Costenoble, R., Heinemann, M., Hucka, M., Le Novere, N., Li, P., Liebermeister, W., Mo, M. L., Oliveira, A. P., Petranovic, D., Pettifer, S., Simeonidis, E., Smallbone, K., Spasic, I., Weichart, D., Brent, R., Broomhead, D. S., Westerhoff, H. V., Kirdar, B., Penttila, M., Klipp, E., Palsson, B. O., Sauer, U., Oliver, S. G., Mendes, P., Nielsen, J., Kell, D. B. (2008). "A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology." Nat Biotechnol 26:1155-1160.18846089