Acid phosphatase PHO12 (P38693)

Identification
NameAcid phosphatase PHO12
SynonymsNot Available
Gene NamePHO12
Enzyme Class
Biological Properties
General FunctionInvolved in acid phosphatase activity
Specific FunctionA phosphate monoester + H(2)O = an alcohol + phosphate
Cellular LocationCytoplasmic
SMPDB Pathways
Riboflavin metabolismPW002443 ThumbThumb?image type=greyscaleThumb?image type=simple
Vitamin B1/Thiamine metabolismPW002486 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG Pathways
Riboflavin metabolismec00740 Map00740
SMPDB Reactions
Thiamine monophosphate + water → Thiamine + phosphate
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
YMDB00164Thiamine monophosphateShow
YMDB00220ThiamineShow
YMDB00890waterShow
YMDB00907phosphateShow
GO Classification
Component
Not Available
Function
phosphoric ester hydrolase activity
phosphatase activity
acid phosphatase activity
catalytic activity
hydrolase activity
hydrolase activity, acting on ester bonds
Process
Not Available
Gene Properties
Chromosome Locationchromosome 8
LocusYHR215W
Gene Sequence>1404 bp ATGTTGAAGTCAGCCGTTTATTCAATTTTAGCCGCTTCTTTGGTTAATGCAGGTACCATA CCCCTCGGAAAGTTATCTGACATTGACAAAATCGGAACTCAAACGGAAATTTTCCCATTT TTGGGTGGTTCTGGGCCATACTACTCTTTCCCTGGTGATTATGGTATTTCTCGTGATTTG CCGGAAAGTTGTGAAATGAAGCAAGTGCAAATGGTTGGTAGACACGGTGAAAGATACCCC ACTGTCAGCAAAGCCAAAAGTATCATGACAACGTGGTACAAATTGAGTAACTATACCGGT CAATTCAGCGGAGCATTGTCTTTCTTGAACGATGACTACGAATTTTTCATTCGTGACACC AAAAACCTAGAAATGGAAACCACACTTGCCAATTCGGTCAATGTTTTGAACCCATATACC GGTGAGATGAATGCTAAGAGACACGCTCGTGATTTCTTGGCGCAATATGGCTACATGGTC GAAAACCAAACCAGTTTTGCCGTTTTTACGTCTAACTCGAACAGATGTCATGATACTGCC CAGTATTTCATTGACGGTTTGGGTGATAAATTCAACATATCCTTGCAAACCATCAGTGAA GCCGAGTCTGCTGGTGCCAATACTCTGAGTGCCCACCATTCGTGTCCTGCTTGGGACGAT GATGTCAACGATGACATTTTGAAAAAATATGATACCAAATATTTGAGTGGTATTGCCAAG AGATTAAACAAGGAAAACAAGGGTTTGAATCTGACTTCAAGTGATGCAAACACTTTTTTT GCATGGTGTGCATATGAAATAAACGCTAGAGGTTACAGTGACATCTGTAACATCTTCACC AAAGATGAATTGGTCCGTTTCTCCTACGGCCAAGACTTGGAAACTTATTATCAAACGGGA CCAGGCTATGACGTCGTCAGATCCGTCGGTGCCAACTTGTTCAACGCTTCAGTGAAACTA CTAAAGGAAAGTGAGGTCCAGGACCAAAAGGTTTGGTTGAGTTTCACCCACGATACCGAT ATTCTGAACTATTTGACCACTATCGGCATAATCGATGACCAAAATAACTTGACCGCCGAA CATGTTCCATTCATGGAAAACACTTTCCACAGATCCTGGTACGTTCCACAAGGTGCTCGT GTTTACACTGAAAAGTTCCAGTGTTCCAATGACACCTATGTTAGATACGTCATCAACGAT GCTGTCGTTCCAATTGAAACCTGTTCTACTGGTCCAGGGTTCTCTTGTGAAATAAATGAC TTCTACGGCTATGCTGAAAAGAGAGTAGCCGGTACTGACTTCCTAAAGGTCTGTAACGTC AGCAGCGTCAGTAACTCTACTGAATTGACCTTTTTCTGGGACTGGAATACCAAGCACTAC AACGACACTTTATTAAAACAGTAA
Protein Properties
Pfam Domain Function
Protein Residues467
Protein Molecular Weight52699.30078
Protein Theoretical pI4.77
Signalling Regions
  • 1-17
Transmembrane Regions
  • None
Protein Sequence>Acid phosphatase PHO12 MLKSAVYSILAASLVNAGTIPLGKLSDIDKIGTQTEIFPFLGGSGPYYSFPGDYGISRDL PESCEMKQVQMVGRHGERYPTVSKAKSIMTTWYKLSNYTGQFSGALSFLNDDYEFFIRDT KNLEMETTLANSVNVLNPYTGEMNAKRHARDFLAQYGYMVENQTSFAVFTSNSNRCHDTA QYFIDGLGDKFNISLQTISEAESAGANTLSAHHSCPAWDDDVNDDILKKYDTKYLSGIAK RLNKENKGLNLTSSDANTFFAWCAYEINARGYSDICNIFTKDELVRFSYGQDLETYYQTG PGYDVVRSVGANLFNASVKLLKESEVQDQKVWLSFTHDTDILNYLTTIGIIDDQNNLTAE HVPFMENTFHRSWYVPQGARVYTEKFQCSNDTYVRYVINDAVVPIETCSTGPGFSCEIND FYGYAEKRVAGTDFLKVCNVSSVSNSTELTFFWDWNTKHYNDTLLKQ
References
External Links
ResourceLink
Saccharomyces Genome Database PHO12
Uniprot IDP38693
Uniprot NamePPAC_YEAST
GenBank Gene IDU00029
Genebank Protein ID458917
General Reference
  • Johnston, M., Andrews, S., Brinkman, R., Cooper, J., Ding, H., Dover, J., Du, Z., Favello, A., Fulton, L., Gattung, S., et, a. l. .. (1994). "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII." Science 265:2077-2082.8091229
  • Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106