Showing Reaction 1214

5-Diphosphoinositol pentakisphosphate + water → Myo-Inositol hexakisphosphate + phosphate + hydron
Thumb+Thumb→Thumb+Thumb+2.0Thumb

Enzymes

  1. Diphosphoinositol polyphosphate phosphohydrolase DDP1

Cellular Locations

  • cytoplasm

References

  • Mo, M. L., Palsson, B. O., Herrgard, M. J. (2009). "Connecting extracellular metabolomic measurements to intracellular flux states in yeast." BMC Syst Biol 3:37.19321003
  • Safrany, S. T., Ingram, S. W., Cartwright, J. L., Falck, J. R., McLennan, A. G., Barnes, L. D., Shears, S. B. (1999). "The diadenosine hexaphosphate hydrolases from Schizosaccharomyces pombe and Saccharomyces cerevisiae are homologues of the human diphosphoinositol polyphosphate phosphohydrolase. Overlapping substrate specificities in a MutT-type protein." J Biol Chem 274:21735-21740.10419486