Putative phosphoglycerate mutase DET1 (Q99288)

Identification
NamePutative phosphoglycerate mutase DET1
Synonyms
  • Decreased ergosterol transport protein 1
  • Phosphoglyceromutase DET1
Gene NameDET1
Enzyme Class
Biological Properties
General FunctionInvolved in catalytic activity
Specific FunctionInvolved, either directly or indirectly, in the bidirectional transport of sterols between the endoplasmic reticulum and the plasma membrane
Cellular LocationCytoplasm. Nucleus
SMPDB PathwaysNot Available
KEGG Pathways
Glycolysis / Gluconeogenesisec00010 Map00010
Methane metabolismec00680 Map00680
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
YMDB003413-Phosphoglyceric acidShow
YMDB006712,3-bisphospho-D-glyceric acidShow
YMDB006752-phospho-D-glyceric acidShow
YMDB007563-phospho-D-glyceric acidShow
YMDB009852-phospho-d-glycerateShow
GO Classification
Component
Not Available
Function
catalytic activity
Process
metabolic process
Gene Properties
Chromosome Locationchromosome 4
LocusYDR051C
Gene Sequence>1005 bp ATGTGTGAAGAGAATGTTCATGTTAGTGAAGATGTTGCTGGCAGTCACGGTTCTTTTACG AATGCCAGACCTAGGTTAATTGTACTAATAAGGCATGGGGAAAGCGAATCAAATAAAAAC AAGGAGGTCAATGGTTATATTCCTAACCATCTGATTTCTTTAACGAAAACAGGTCAAATC CAAGCTAGACAAGCTGGTATTGACTTATTACGTGTTTTAAACGTAGACGATCACAACTTG GTGGAGGATTTGGCTAAGAAGTATATTAAAGATGAAAGTAGCAGGAGAACTTTACCGCTG AAGGACTATACCAGGCTGAGTAGAGAAAAAGACACAAACATAGTTTTTTATACATCACCC TATAGAAGAGCAAGGGAAACATTGAAAGGTATTTTGGACGTCATCGATGAATATAATGAA TTAAACAGTGGTGTTCGTATATGTGAAGATATGAGATATGATCCACATGGTAAACAGAAA CATGCATTTTGGCCGAGAGGACTTAATAATACTGGTGGTGTTTACGAAAATAATGAAGAT AATATTTGTGAAGGGAAGCCTGGAAAATGTTATCTGCAATATCGGGTTAAGGATGAGCCA AGAATAAGGGAACAAGATTTTGGTAATTTCCAAAAAATCAATAGCATGCAGGACGTTATG AAGAAGAGATCTACGTATGGTCATTTCTTCTTCAGATTCCCTCATGGAGAAAGTGCGGCA GATGTATATGACAGAGTCGCCAGTTTCCAAGAGACTTTATTCAGGCACTTCCATGATAGG CAAGAGAGAAGACCCAGAGATGTTGTTGTCCTAGTTACACATGGTATTTATTCCAGAGTA TTCCTGATGAAATGGTTTAGATGGACATACGAAGAGTTTGAATCGTTTACCAATGTTCCT AACGGGAGCGTAATGGTGATGGAACTGGACGAATCCATCAATAGATACGTCCTGAGGACC GTGCTACCCAAATGGACTGATTGTGAGGGAGACCTAACTACATAG
Protein Properties
Pfam Domain Function
Protein Residues334
Protein Molecular Weight39171.80078
Protein Theoretical pI7.37
Signalling Regions
  • None
Transmembrane Regions
  • None
Protein Sequence>Putative phosphoglycerate mutase DET1 MCEENVHVSEDVAGSHGSFTNARPRLIVLIRHGESESNKNKEVNGYIPNHLISLTKTGQI QARQAGIDLLRVLNVDDHNLVEDLAKKYIKDESSRRTLPLKDYTRLSREKDTNIVFYTSP YRRARETLKGILDVIDEYNELNSGVRICEDMRYDPHGKQKHAFWPRGLNNTGGVYENNED NICEGKPGKCYLQYRVKDEPRIREQDFGNFQKINSMQDVMKKRSTYGHFFFRFPHGESAA DVYDRVASFQETLFRHFHDRQERRPRDVVVLVTHGIYSRVFLMKWFRWTYEEFESFTNVP NGSVMVMELDESINRYVLRTVLPKWTDCEGDLTT
References
External Links
ResourceLink
Saccharomyces Genome Database DET1
Uniprot IDQ99288
Uniprot NameDET1_YEAST
GenBank Gene IDZ49209
Genebank Protein ID798903
General Reference
  • Jacq, C., Alt-Morbe, J., Andre, B., Arnold, W., Bahr, A., Ballesta, J. P., Bargues, M., Baron, L., Becker, A., Biteau, N., Blocker, H., Blugeon, C., Boskovic, J., Brandt, P., Bruckner, M., Buitrago, M. J., Coster, F., Delaveau, T., del Rey, F., Dujon, B., Eide, L. G., Garcia-Cantalejo, J. M., Goffeau, A., Gomez-Peris, A., Zaccaria, P., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome IV." Nature 387:75-78.9169867
  • Brandt, P., Ramlow, S., Otto, B., Bloecker, H. (1996). "Nucleotide sequence analysis of a 32,500 bp region of the right arm of Saccharomyces cerevisiae chromosome IV." Yeast 12:85-90.8789263
  • Huh, W. K., Falvo, J. V., Gerke, L. C., Carroll, A. S., Howson, R. W., Weissman, J. S., O'Shea, E. K. (2003). "Global analysis of protein localization in budding yeast." Nature 425:686-691.14562095
  • Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106
  • Albuquerque, C. P., Smolka, M. B., Payne, S. H., Bafna, V., Eng, J., Zhou, H. (2008). "A multidimensional chromatography technology for in-depth phosphoproteome analysis." Mol Cell Proteomics 7:1389-1396.18407956
  • Sullivan, D. P., Georgiev, A., Menon, A. K. (2009). "Tritium suicide selection identifies proteins involved in the uptake and intracellular transport of sterols in Saccharomyces cerevisiae." Eukaryot Cell 8:161-169.19060182