Mitochondrial ornithine carrier protein (Q12375)

Identification
NameMitochondrial ornithine carrier protein
SynonymsNot Available
Gene NameORT1
Enzyme ClassNot Available
Biological Properties
General FunctionInvolved in binding
Specific FunctionRequired for arginine biosynthesis. May participate in the export of matrix-made ornithine into the cytosol
Cellular LocationMitochondrion inner membrane; Multi-pass membrane protein
SMPDB PathwaysNot Available
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
YMDB00862hydronShow
GO Classification
Component
cell part
membrane
Function
binding
Process
establishment of localization
transport
transmembrane transport
Gene Properties
Chromosome Locationchromosome 15
LocusYOR130C
Gene Sequence>879 bp ATGGAGGACAGTAAAAAGAAAGGATTAATAGAAGGCGCTATACTCGATATAATAAACGGT TCCATTGCAGGCGCCTGTGGTAAGGTGATCGAGTTTCCTTTCGATACTGTGAAAGTCAGG TTGCAAACACAAGCATCCAACGTGTTCCCAACAACATGGTCTTGTATAAAATTTACTTAC CAAAATGAAGGAATAGCACGAGGGTTTTTTCAAGGCATTGCTTCACCTTTAGTTGGAGCA TGTCTGGAGAACGCGACATTATTTGTGTCTTATAACCAATGTTCTAAATTTTTAGAAAAA CATACAAACGTTTCCCCGTTGGGGCAAATCCTGATCTCTGGTGGAGTAGCGGGTTCATGT GCTAGTTTAGTTTTGACACCCGTGGAGCTGGTGAAGTGTAAGTTGCAGGTTGCGAACTTA CAAGTTGCATCAGCTAAAACGAAACATACAAAGGTGTTGCCTACAATAAAAGCAATTATA ACTGAGAGAGGATTGGCAGGATTGTGGCAAGGGCAATCGGGCACTTTTATTCGAGAAAGC TTCGGTGGTGTTGCCTGGTTTGCAACCTACGAAATAGTTAAGAAGTCGTTGAAAGATAGG CACTCCCTTGATGACCCAAAAAGAGATGAAAGTAAGATATGGGAACTACTTATTAGTGGA GGGAGCGCTGGATTGGCATTCAACGCCAGTATTTTTCCTGCGGATACTGTGAAATCAGTA ATGCAAACTGAACATATAAGCCTCACCAATGCGGTGAAGAAGATATTTGGCAAATTTGGA CTAAAGGGTTTTTATCGAGGACTGGGTATAACCCTTTTTAGGGCAGTACCAGCAAACGCT GCAGTTTTTTACATCTTTGAGACTCTTTCTGCACTTTAA
Protein Properties
Pfam Domain Function
Protein Residues292
Protein Molecular Weight31579.5
Protein Theoretical pI9.73
Signalling Regions
  • None
Transmembrane Regions
  • 14-34
  • 69-89
  • 104-124
  • 171-187
  • 213-233
  • 267-287
Protein Sequence>Mitochondrial ornithine carrier protein MEDSKKKGLIEGAILDIINGSIAGACGKVIEFPFDTVKVRLQTQASNVFPTTWSCIKFTY QNEGIARGFFQGIASPLVGACLENATLFVSYNQCSKFLEKHTNVFPLGQILISGGVAGSC ASLVLTPVELVKCKLQVANLQVASAKTKHTKVLPTIKAIITERGLAGLWQGQSGTFIRES FGGVAWFATYEIVKKSLKDRHSLDDPKRDESKIWELLISGGSAGLAFNASIFPADTVKSV MQTEHISLTNAVKKIFGKFGLKGFYRGLGITLFRAVPANAAVFYIFETLSAL
References
External Links
ResourceLink
Saccharomyces Genome Database ORT1
Uniprot IDQ12375
Uniprot NameORT1_YEAST
GenBank Gene IDX87414
Genebank Protein ID1668788
General Reference
  • Crabeel, M., Soetens, O., De Rijcke, M., Pratiwi, R., Pankiewicz, R. (1996). "The ARG11 gene of Saccharomyces cerevisiae encodes a mitochondrial integral membrane protein required for arginine biosynthesis." J Biol Chem 271:25011-25018.8798783
  • Wiemann, S., Rechmann, S., Benes, V., Voss, H., Schwager, C., Vlcek, C., Stegemann, J., Zimmermann, J., Erfle, H., Paces, V., Ansorge, W. (1996). "Sequencing and analysis of 51 kb on the right arm of chromosome XV from Saccharomyces cerevisiae reveals 30 open reading frames." Yeast 12:281-288.8904341
  • Voss, H., Benes, V., Andrade, M. A., Valencia, A., Rechmann, S., Teodoru, C., Schwager, C., Paces, V., Sander, C., Ansorge, W. (1997). "DNA sequencing and analysis of 130 kb from yeast chromosome XV." Yeast 13:655-672.9200815
  • Dujon, B., Albermann, K., Aldea, M., Alexandraki, D., Ansorge, W., Arino, J., Benes, V., Bohn, C., Bolotin-Fukuhara, M., Bordonne, R., Boyer, J., Camasses, A., Casamayor, A., Casas, C., Cheret, G., Cziepluch, C., Daignan-Fornier, B., Dang, D. V., de Haan, M., Delius, H., Durand, P., Fairhead, C., Feldmann, H., Gaillon, L., Kleine, K., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome XV." Nature 387:98-102.9169874
  • Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106