Serine/threonine-protein kinase PKH2 (Q12236)
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| Name | Serine/threonine-protein kinase PKH2 | |||||||||||||
| Synonyms |
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| Gene Name | PKH2 | |||||||||||||
| Enzyme Class | Not Available | |||||||||||||
| Biological Properties | ||||||||||||||
| General Function | regulation of nuclear-transcribed mRNA poly(A) tail shortening | |||||||||||||
| Specific Function | Serine/threonine-protein kinase which is part sphingolipid-mediated signaling pathway that is required for the internalization step of endocytosis by regulating eisosome assembly and organization, and modulating the organization of the plasma membrane. Phosphorylates and activates PKC1. Activates YPK1 and YPK2, 2 components of signaling cascade required for maintenance of cell wall integrity. Required for stress-induced P-body assembly and regulates global mRNA decay at the deadenylation step. | |||||||||||||
| Cellular Location | Not Available | |||||||||||||
| SMPDB Pathways |
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| KEGG Pathways | Not Available | |||||||||||||
| SMPDB Reactions | Not Available | |||||||||||||
| KEGG Reactions | Not Available | |||||||||||||
| Metabolites |
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| GO Classification |
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| Gene Properties | ||||||||||||||
| Chromosome Location | Not Available | |||||||||||||
| Locus | ||||||||||||||
| Gene Sequence | >3246 bp ATGTATTTTGATAAGGATAATTCCATGAGCCCTAGGCCGTTATTGCCAAGTGATGAGCAG AAGCTAAACATTAATCTTCTAACGAAAAAGGAGAAATTCTCGCATTTAGACCCCCATTAT GACGCAAAAGCCACTCCACAAAGAAGCACTTCGAATAGAAACGTTGGCGATTTACTTTTG GAAAAAAGAACCGCTAAGCCTATGATTCAAAAGGCCTTGACGAATACGGATAATTTCATT GAAATGTACCATAATCAGCAGAGAAAAAATCTTGATGATGACACTATTAAAGAAGTAATG ATTAATGATGAAAACGGAAAAACTGTCGCTAGTACCAACGACGGCAGATATGACAACGAT TACGATAATAACGATATTAATGACCAAAAAACTTTGGATAATATAGCGGGAAGTCCCCAC ATGGAAAAAAATCGAAACAAAGTAAAGATTGAACATGACTCTTCATCTCAAAAACCAATA GCTAAAGAGTCATCCAAAGCCCAAAAAAATATAATCAAAAAGGGAATCAAGGACTTTAAA TTTGGTAGTGTAATAGGTGATGGCGCGTATTCTACTGTAATGTTAGCGACGTCGATTGAT ACCAAAAAGAGGTACGCCGCAAAAGTACTAAACAAAGAATATTTAATACGCCAGAAGAAA GTCAAATACGTCAGCATAGAAAAAACCGCCCTTCAAAAGCTCAATAATTCTCCTAGTGTT GTGCGATTATTTTCCACTTTTCAGGATGAATCAAGCCTATACTTTCTCTTAGAGTATGCC CCCAATGGGGACTTTCTTTCTTTAATGAAAAAATACGGTTCATTAGACGAAACCTGCGCA CGATATTATGCTGCGCAAATAATAGATGCCATAGACTACTTACATTCCAACGGTATTATT CATAGAGATATAAAACCAGAAAATATTCTTTTAGATGGAGAAATGAAGATCAAACTGACT GATTTTGGTACTGCGAAGTTACTGAATCCTACAAATAATAGCGTTTCGAAACCAGAATAC GATTTATCAACAAGGTCGAAATCTTTCGTTGGAACTGCAGAATACGTATCTCCAGAACTT TTAAATGACAGTTTTACAGACTATCGTTGCGATATTTGGGCCTTCGGATGTATACTTTTC CAGATGATTGCCGGAAAACCACCATTCAAAGCTACCAATGAATACTTGACTTTCCAAAAG GTAATGAAAGTTCAGTACGCCTTTACACCAGGTTTCCCACTTATTATCAGAGATTTGGTT AAGAAAATCTTAGTAAAAAACTTAGACCGAAGATTGACGATAAGCCAAATTAAGGAACAT CATTTTTTCAAAGATTTGAATTTTAAAGACGGCTCTGTTTGGTCAAAAACGCCTCCAGAG ATCAAACCATATAAAATCAACGCCAAATCCATGCAGGCAATGCCAAGCGGAAGCGATAGA AAACTGGTGAAGAAATCAGTCAACACACTTGGCAAATCGCATCTAGTGACTCAAAGGTCA GCTTCAAGTCCCTCTGTTGAGGAAACTACTCATTCAACCCTATACAATAACAATACTCAC GCTTCTACTGAAAGTGAAATATCAATAAAGAAGAGACCCACTGATGAAAGAACAGCGCAG ATACTTGAAAATGCAAGAAAGGGTATAAACAATAGGAAAAATCAACCAGGCAAGAGAACA CCAAGTGGTGCAGCTTCTGCTGCCCTAGCAGCTTCTGCTGCTTTAACCAAGAAAACCATG CAAAGCTATCCAACTTCTAGTTCGAAAAGTAGCAGGTCAAGCTCTCCTGCGACAACATCA AGACCAGGAACTTATAAGCGTACTTCTTCTACAGAAAGTAAACCATTTGCCAAATCTCCA CCTTTGTCAGCATCAGTTTTATCGTCAAAAGTCCCAATGCCTCCATACACACCTCCAATG TCGCCCCCTATGACACCATATGATACATATCAAATGACACCTCCCTATACGACAAAACAG CAGGATTATTCTGATACCGCAATTGCCGCACCTAAGCCTTGTATTAGTAAGCAAAATGTT AAAAATAGCACAGATTCTCCCTTGATGAACAAGCAAGATATTCAATGGTCCTTTTACCTG AAAAACATCAACGAACATGTACTAAGGACGGAAAAACTGGATTTTGTTACCACAAATTAC GATATCTTAGAGAAGAAAATGCTTAAACTAAATGGTTCATTGTTAGATCCTCAACTGTTT GGTAAGCCTAGACATACTTTTTTATCCCAAGTAGCTAGGAGTGGGGGAGAGGTTACAGGT TTTCGAAATGATCCAACTATGACTGCTTATTCCAAAACAGAAGATACGTACTATTCGAAA AATATTATCGATTTGCAGCTCTTGGAAGATGATTATCGAATTGAAGGAGGTGACTTATCG GAGTTGCTTACTAACAGAAGCGGAGAAGGGTACAAATGCAATCAAAACAGCTCACCAATG AAAGACGATGATAAATCCGAATCTAACAATAAAGGAAGCTCTGTTTTTTCTGGCAAGATT AAAAAATTATTTCACCCTACCTCAGCAGCTGAAACGCTCTCTTCCTCTGATGAAAAAACC AAGTACTATAAACGAACCATTGTAATGACATCATTTGGAAGGTTTCTAGTATTTGCCAAG AGGAGGCAGCCAAATCCAGTTACAAATTTAAAGTATGAACTAGAATATGACATAAATTTG CGTCAACAGGGTACCAAAATAAAAGAACTAATCATTCCCTTGGAAATGGGAACTAATCAT ATAGTTGTGATTCAGACACCTTACAAGTCATTTCTTTTGAGCACTGATAAAAAAACCACG AGCAAATTGTTTACTGTTCTCAAAAAAATTCTTAATTCGAATACAAATAAAATAGAGAAA GAACTGTTGCAAAGAAACCAAAAGGTAATTGAAAGAAGAACATCATCATCCGGAAGAGCC ATACCTAAAGATCTTCCAACTTCCAAGTCTCCTTCGCCAAAACCCAGGACGCATAGCCAA TCTCCATCAATTTCAAAGCACAATTCGTTTTCTGAATCGATTAATAGCGCTAAGAGCAAC AGATCAAGCAGAATTTTTGAAACCTTTATCAATGCCAAGGAACAAAATTCAAAAAAACAC GCTGCTCCAGTACCGTTAACCAGTAAATTAGTTAACGGATTGCCAAAAAGACAAGTTACC GTGGGATTAGGTCTAAACACAGGAACAAATTTCAAAAACTCATCTGCAAAATCGAAGAGG TCGTAA | |||||||||||||
| Protein Properties | ||||||||||||||
| Pfam Domain Function | Not Available | |||||||||||||
| Protein Residues | 1081 | |||||||||||||
| Protein Molecular Weight | 121659.06 | |||||||||||||
| Protein Theoretical pI | Not Available | |||||||||||||
| Signalling Regions | Not Available | |||||||||||||
| Transmembrane Regions | Not Available | |||||||||||||
| Protein Sequence | >Serine/threonine-protein kinase PKH2 MYFDKDNSMSPRPLLPSDEQKLNINLLTKKEKFSHLDPHYDAKATPQRSTSNRNVGDLLL EKRTAKPMIQKALTNTDNFIEMYHNQQRKNLDDDTIKEVMINDENGKTVASTNDGRYDND YDNNDINDQKTLDNIAGSPHMEKNRNKVKIEHDSSSQKPIAKESSKAQKNIIKKGIKDFK FGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSPSV VRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGII HRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPEL LNDSFTDYRCDIWAFGCILFQMIAGKPPFKATNEYLTFQKVMKVQYAFTPGFPLIIRDLV KKILVKNLDRRLTISQIKEHHFFKDLNFKDGSVWSKTPPEIKPYKINAKSMQAMPSGSDR KLVKKSVNTLGKSHLVTQRSASSPSVEETTHSTLYNNNTHASTESEISIKKRPTDERTAQ ILENARKGINNRKNQPGKRTPSGAASAALAASAALTKKTMQSYPTSSSKSSRSSSPATTS RPGTYKRTSSTESKPFAKSPPLSASVLSSKVPMPPYTPPMSPPMTPYDTYQMTPPYTTKQ QDYSDTAIAAPKPCISKQNVKNSTDSPLMNKQDIQWSFYLKNINEHVLRTEKLDFVTTNY DILEKKMLKLNGSLLDPQLFGKPRHTFLSQVARSGGEVTGFRNDPTMTAYSKTEDTYYSK NIIDLQLLEDDYRIEGGDLSELLTNRSGEGYKCNQNSSPMKDDDKSESNNKGSSVFSGKI KKLFHPTSAAETLSSSDEKTKYYKRTIVMTSFGRFLVFAKRRQPNPVTNLKYELEYDINL RQQGTKIKELIIPLEMGTNHIVVIQTPYKSFLLSTDKKTTSKLFTVLKKILNSNTNKIEK ELLQRNQKVIERRTSSSGRAIPKDLPTSKSPSPKPRTHSQSPSISKHNSFSESINSAKSN RSSRIFETFINAKEQNSKKHAAPVPLTSKLVNGLPKRQVTVGLGLNTGTNFKNSSAKSKR S | |||||||||||||
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| External Links |
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| General Reference | Not Available | |||||||||||||