Probable electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (Q08822)

Identification
NameProbable electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial
Synonyms
  • ETF-QO
  • ETF-ubiquinone oxidoreductase
  • Electron-transferring-flavoprotein dehydrogenase
  • ETF dehydrogenase
Gene NameNot Available
Enzyme Class
Biological Properties
General FunctionInvolved in iron-sulfur cluster binding
Specific FunctionAccepts electrons from ETF and reduces ubiquinone
Cellular LocationMitochondrion inner membrane
SMPDB PathwaysNot Available
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
YMDB00088Ubiquinone Q1Show
GO Classification
Component
Not Available
Function
oxidoreductase activity
oxidoreductase activity, acting on the CH-NH group of donors
oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor
electron-transferring-flavoprotein dehydrogenase activity
catalytic activity
Process
oxidation reduction
metabolic process
Gene Properties
Chromosome LocationNot Available
LocusYOR356W
Gene Sequence>1896 bp ATGATTAAGTTCACTAACGAGAACTTAATTAGAGGGATCCGAATGACGATTTCCGCAAAA TCTCGTCATTTGGCTCTAGGGACAGATATGACGAGAAAGTTTAGCTTGTCGTGTAGGTTT TTGAACAAAGCAAATCTTACTGAAGAAGAGAAAGAGTTGTTAAATGAACCAAGGGCGCGC GACTATGTGGATGTTTGTATAGTTGGAGGAGGGCCTGCGGGATTAGCAACAGCAATCAAA TTAAAACAGTTAGACAATTCGTCAGGAACAGGCCAATTGCGTGTCGTTGTTCTTGAAAAA TCCAGTGTATTGGGTGGACAAACTGTTTCCGGCGCTATATTGGAACCGGGAGTGTGGAAA GAACTATTCCCTGATGAAAAGTCTGACATTGGCATTCCGTTACCAAAGGAGTTAGCTACG TTGGTAACTAAAGAACATTTGAAATTTTTAAAGGGGAAATGGGCGATCAGCGTTCCAGAA CCATCTCAAATGATCAATAAAGGACGTAATTATATTGTCTCTTTGAACCAAGTCGTCGGA TATTTAGGAGAAAAGGCAGAAGAAGTAGGAGTTGAAGTTTACCCCGGAATAGCTGTCTCG GATCTCATATATGATGAAAACAACGCCGTTAAGGGTGTAATTACTAAAGATGCTGGTATT TCGAAGTCCGGTAAGCCTAAGGAAACCTTCGAACGTGGGATGGAATTTTGGGCTAGACAA ACTGTATTAGCAGAGGGCTGTCATGGTTCCTTAACAAAACAAGCCTTGGCAAAATATGAT TTAAGAAAAGGCAGACAGCACCAAACTTATGGATTAGGTATTAAAGAAGTTTGGGAAGTC AAGCCGGAGAATTTTAACAAGGGATTTGCAGCTCATACCATGGGGTACCCGTTGACAAAT GATGTTTATGGCGGTGGTTTCCAGTACCATTTTGGTGATGGGCTGGTCACTGTGGGCCTT GTCGTGGGGTTAGATTATAAGAATCCCTATGTTTCACCTTACAAAGAGTTTCAAAAGATG AAACATCATCCATACTATTCAAAAGTTTTAGAAGGAGGTAAGTGTATCGCTTATGCTGCA AGAGCATTGAATGAAGGTGGACTGCAATCTGTACCCAAGTTGAATTTCCCTGGTGGTGTT TTGGTAGGGGCTAGCGCGGGTTTCATGAACGTTCCAAAGATCAAGGGTACTCATACTGCG ATGAAGAGTGGATTACTTGCCGCTGAAAGTATCTTTGAGTCCATAAAAGGGTTACCTGTC TTAGAAGAGGTTGAAGACGAAGACGCCAAAATGGCTATGTTTGATAAGGAGGCAACTATT AACTTGGAATCATATGAAAGTGCATTCAAAGAATCATCGATATATAAGGAACTATACGAA GTGCGTAATATTAGACCGTCCTTCAGCGGGAAACTTGGTGGATATGGTGGTATGATCTAC TCTGGAATCGATTCTTTGATATTGAAGGGAAAAGTTCCGTGGACACTGAAATTTGATGAA AAAAATGACGGTGAAATTTTGGAACCTGCTTCCAAGTACAAACCGATAGAATACCCCAAG CCTGATGGTGTGATATCCTTTGATATATTGACCTCCGTGTCTAGAACCGGAACCTACCAT GATGATGATGAACCATGTCACTTGAGGGTTCCTGGACAAGATATGGTAAAGTACGCCGAG AGAAGCTTTCCCGTTTGGAAAGGTGTTGAATCGAGGTTCTGCCCAGCAGGTGTCTACGAA TTCGTCAAAGATGAAAAATCGCCTGTGGGTACGAGACTGCAAATCAATTCACAAAATTGT ATCCATTGCAAGACCTGTGATATTAAGGCGCCCAGACAAGATATTACTTGGAAAGTACCC GAAGGTGGAGATGGACCAAAGTACACGCTAACTTAA
Protein Properties
Pfam Domain Function
Protein Residues631
Protein Molecular Weight69633.39844
Protein Theoretical pI7.95
Signalling Regions
  • None
Transmembrane Regions
  • None
Protein Sequence>Probable electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial MIKFTNENLIRGIRMTISAKSRHLALGTDMTRKFSLSCRFLNKANLTEEEKELLNEPRAR DYVDVCIVGGGPAGLATAIKLKQLDNSSGTGQLRVVVLEKSSVLGGQTVSGAILEPGVWK ELFPDEKSDIGIPLPKELATLVTKEHLKFLKGKWAISVPEPSQMINKGRNYIVSLNQVVG YLGEKAEEVGVEVYPGIAVSDLIYDENNAVKGVITKDAGISKSGKPKETFERGMEFWARQ TVLAEGCHGSLTKQALAKYDLRKGRQHQTYGLGIKEVWEVKPENFNKGFAAHTMGYPLTN DVYGGGFQYHFGDGLVTVGLVVGLDYKNPYVSPYKEFQKMKHHPYYSKVLEGGKCIAYAA RALNEGGLQSVPKLNFPGGVLVGASAGFMNVPKIKGTHTAMKSGLLAAESIFESIKGLPV LEEVEDEDAKMAMFDKEATINLESYESAFKESSIYKELYEVRNIRPSFSGKLGGYGGMIY SGIDSLILKGKVPWTLKFDEKNDGEILEPASKYKPIEYPKPDGVISFDILTSVSRTGTYH DDDEPCHLRVPGQDMVKYAERSFPVWKGVESRFCPAGVYEFVKDEKSPVGTRLQINSQNC IHCKTCDIKAPRQDITWKVPEGGDGPKYTLT
References
External Links
ResourceLink
Saccharomyces Genome Database YOR356W
Uniprot IDQ08822
Uniprot NameETFD_YEAST
GenBank Gene IDZ75264
Genebank Protein ID1420774
General Reference
  • Dujon, B., Albermann, K., Aldea, M., Alexandraki, D., Ansorge, W., Arino, J., Benes, V., Bohn, C., Bolotin-Fukuhara, M., Bordonne, R., Boyer, J., Camasses, A., Casamayor, A., Casas, C., Cheret, G., Cziepluch, C., Daignan-Fornier, B., Dang, D. V., de Haan, M., Delius, H., Durand, P., Fairhead, C., Feldmann, H., Gaillon, L., Kleine, K., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome XV." Nature 387:98-102.9169874
  • Grandier-Vazeille, X., Bathany, K., Chaignepain, S., Camougrand, N., Manon, S., Schmitter, J. M. (2001). "Yeast mitochondrial dehydrogenases are associated in a supramolecular complex." Biochemistry 40:9758-9769.11502169
  • Huh, W. K., Falvo, J. V., Gerke, L. C., Carroll, A. S., Howson, R. W., Weissman, J. S., O'Shea, E. K. (2003). "Global analysis of protein localization in budding yeast." Nature 425:686-691.14562095
  • Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106
  • Sickmann, A., Reinders, J., Wagner, Y., Joppich, C., Zahedi, R., Meyer, H. E., Schonfisch, B., Perschil, I., Chacinska, A., Guiard, B., Rehling, P., Pfanner, N., Meisinger, C. (2003). "The proteome of Saccharomyces cerevisiae mitochondria." Proc Natl Acad Sci U S A 100:13207-13212.14576278