Phosphopantothenoylcysteine decarboxylase subunit VHS3 (Q08438)

Identification
NamePhosphopantothenoylcysteine decarboxylase subunit VHS3
Synonyms
  • Viable in a HAL3 SIT4 background protein 3
Gene NameVHS3
Enzyme ClassNot Available
Biological Properties
General Functioncoenzyme A biosynthetic process
Specific FunctionComponent of the phosphopantothenoylcysteine decarboxylase (PPCDC) involved in the coenzyme A synthesis. Acts as an inhibitory subunit of protein phosphatase PPZ1, which is involved in many cellular processes such as G1-S transition or salt tolerance.
Cellular LocationNot Available
SMPDB Pathways
beta-Alanine metabolismPW002381 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG Pathways
beta-Alanine metabolismec00410 Map00410
SMPDB Reactions
4-Phosphopantothenoylcysteine + hydron → Carbon dioxide + 4'-phosphopantetheine
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
YMDB004004-PhosphopantothenoylcysteineShow
YMDB00862hydronShow
YMDB00912Carbon dioxideShow
YMDB162644'-phosphopantetheineShow
GO Classification
Function
protein phosphatase inhibitor activity
coenzyme A biosynthetic process
cellular monovalent inorganic cation homeostasis
cell cycle
CoA-synthesizing protein complex
phosphopantothenoylcysteine decarboxylase complex
phosphopantothenoylcysteine decarboxylase activity
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>2025 bp ATGACAAACAAATCTAGCCTGAAGAACAATAGGAAAGGGGTTGCTTCGAATACTCTCTCT GGAGCTGAGCAGGCCAATATAGGTTCATCGGCAATGCCTGACACAAATTCTACGGGACCA TTTTCTTCCGTTTCTAGTCTGGACACTCCTGTAGTAAGGAAATCAACTAGTCCCACTGGT TCACAAACTAAGTCAATCATGAATGCTAGCGGAACTTCTGGGGCAGTTGTAAGTAATACA CCAGAGCCAGGGTTAAAAAGGATACCAACTGTTACATTCAGCGATCCAAAGTTGGGTAGT CTCAGGTCGGATGTGGAGCAAACTCCACCTAACCAGGTGGCCAGACAGTCCAGCGAAAAG AAAGCAACGTCTGTACACATCGCAGCGGAGGGTGCAAATCAAGGAAGAAACTTGAAAGAC ATAAATACAAAAGTACCAAAAGATGGCGAGGCTTCTGCTTCTTCTTTTTCGACTCCAACC TCTATTCTCTCCAATGCTGATATGGGGAATAACATATCCAGCCTGCTGGCTAAAAAGCTA AGTTTCACCGGTGGAACAGATTCTATTTTAAACTCTGACAATAGTTCCGATAGCCCCAGA AAGGAGCACCCACATTTCTACGTGGAAGATCCTTTACACACCCCATCAGTTAGATCAAGG TCTAACAGTACTAGTCCTCGCCCCTCTGTGGTAGTGAATACATTTAACCCCATCAACATT GAACGAGAGGGCTCCATATCAAAGACTGGAGAGCCCACATTGTTGGAGTCTGTCTTGGAA GAAGCAATGTCTCCCAATGCAGTCTCAAATCCCTTGAAGAGAGAAAATATTATGACCAAT ATGGATCCAAGGCTTCCCCAAGATGACGGCAAGCTACACGTTCTTTTTGGGGCAACAGGT TCTTTGTCTGTTTTCAAACTCAAGCACATGATCAGAAAATTAGAAGAAATTTACGGAAGG GACAAAATATGCATACAAGTTATACTAACTAACTCAGCAACCAAATTTTTTGCAATGAAG TATATGAGGAAAAATAAGAAACAACACAATAGTATCGATACTTCTTTCAACAGCACCAAT TCTAATGCTGGCAATATAACTGGTAACAAGAAAAAAGTAGCCTCTCTTGAAAAATTTAGC ATTCAGAAGACGTCTTCAAACTCAGCGGCTTCTCAGACAAATAATAAACAGGAGGAAGAA AAACAAATGGCCTCTACTACTGGATTTCCTTCGACACTTGGTGGTAGTCGTACGTACAGC AACTCTTCAAACGTTGTATCGCAACATCCTCAAATTGAACTGCCAGCACATATACAATTT TGGACAGACCAAGACGAGTGGGATGTATGGCGACAACGAACTGATCCTGTATTACACATA GAACTACGTCGTTGGGCAGATATACTAGTTGTCGCACCATTAACCGCAAACACGTTGGCC AAGATTGCCCTTGGTTTATGTGACAACCTTTTGACAAGTGTAATAAGGGCATGGAATCCA ACGTTTCCCATATTCCTAGCGCCTTCAATGGGTAGCGGTACGTTCAATTCCATAATGACT AAAAAACATTTTCGAATTATTCAAGAAGAGATGCCTTGGGTAACTGTATTTAAACCCTCA GAAAAAGTCATGGGCATAAACGGTGACATCGGGTTAAGTGGGATGATGGATGCAAATGAG ATTGTTGGCAAGATAGTCGTCAAACTAGGTGGTTATCCCGATGTTTCTGCGGGAAAGGAA GAAGAAGAGGATGAAGATAACGATGAGGAGGATGATAATAAGAAGAACGATACTGGTGGT AAAGATGAAGATAATGACGACGACGACGATGACGATGATGATGATGACGATGATGACGAC GACGACGACGACGACGACGACGACGACGACGACGATGATGATGATGACGACGATGATGAC GACGATGATGACGACGACGACGACGACGATGAAGATGACGAAGACGAAGATGAAGACGAT GAAGGAAAAAAGAAAGAAGATAAAGGAGGGCTACAGCGATCTTAA
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues674
Protein Molecular Weight73648.495
Protein Theoretical pINot Available
Signalling RegionsNot Available
Transmembrane RegionsNot Available
Protein Sequence>Phosphopantothenoylcysteine decarboxylase subunit VHS3 MTNKSSLKNNRKGVASNTLSGAEQANIGSSAMPDTNSTGPFSSVSSLDTPVVRKSTSPTG SQTKSIMNASGTSGAVVSNTPEPGLKRIPTVTFSDPKLGSLRSDVEQTPPNQVARQSSEK KATSVHIAAEGANQGRNLKDINTKVPKDGEASASSFSTPTSILSNADMGNNISSLLAKKL SFTGGTDSILNSDNSSDSPRKEHPHFYVEDPLHTPSVRSRSNSTSPRPSVVVNTFNPINI EREGSISKTGEPTLLESVLEEAMSPNAVSNPLKRENIMTNMDPRLPQDDGKLHVLFGATG SLSVFKLKHMIRKLEEIYGRDKICIQVILTNSATKFFAMKYMRKNKKQHNSIDTSFNSTN SNAGNITGNKKKVASLEKFSIQKTSSNSAASQTNNKQEEEKQMASTTGFPSTLGGSRTYS NSSNVVSQHPQIELPAHIQFWTDQDEWDVWRQRTDPVLHIELRRWADILVVAPLTANTLA KIALGLCDNLLTSVIRAWNPTFPIFLAPSMGSGTFNSIMTKKHFRIIQEEMPWVTVFKPS EKVMGINGDIGLSGMMDANEIVGKIVVKLGGYPDVSAGKEEEEDEDNDEEDDNKKNDTGG KDEDNDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDEDEDEDD EGKKKEDKGGLQRS
References
External Links
ResourceLink
Saccharomyces Genome Database VHS3
Uniprot IDQ08438
Uniprot NameVHS3
General ReferenceNot Available