| Identification |
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| Name | Probable dolichyl-phosphate-mannose--protein mannosyltransferase 7 |
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| Synonyms | Not Available |
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| Gene Name | PMT7 |
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| Enzyme Class | |
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| Biological Properties |
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| General Function | Involved in mannosyltransferase activity |
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| Specific Function | Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins |
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| Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein |
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| SMPDB Pathways | Not Available |
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| KEGG Pathways | | O-Mannosyl glycan biosynthesis | ec00514 |  |
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| SMPDB Reactions | Not Available |
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| KEGG Reactions | Not Available |
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| Metabolites | | YMDB ID | Name | View |
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| YMDB00937 | dolichyl D-mannosyl phosphate | Show |
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| GO Classification | | Component |
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| cell part | | membrane | | Function |
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| catalytic activity | | transferase activity | | transferase activity, transferring glycosyl groups | | transferase activity, transferring hexosyl groups | | mannosyltransferase activity | | Process |
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| protein amino acid O-linked glycosylation | | metabolic process | | macromolecule metabolic process | | macromolecule modification | | protein modification process | | protein amino acid glycosylation |
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| Gene Properties |
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| Chromosome Location | Not Available |
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| Locus | PMT7 |
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| Gene Sequence | >1989 bp
ATGAAGGACTTGAGATTACAGGGGCCCTACAGAAAGTACATTCCCTATAATATTTTCCAA
CAATGTGGAATTGGTCACTTAAAGACGCTTGATTATATTTTCGCGTTTTTGATTGTTATT
ACCAATTTCACATTAATATGGAAATCGCACTCTTCTTCATTCTGGAACCGACCATGGGAC
AATAATAGTGAACAAGAACTTTCCCAATTAATTCAGTTTTACCTAGACAAGGCTTTTTAC
ATCCATGAATTGCCACCATTTACAATACAGTTCTACTCCATTATTCGAAGATTAAAGATC
GCAGAAAATTTAAGATACGTTTCTTTGTTTTTGAATTCATCGACTTTAGGTTTTCTTTTC
CTGATAACAAGGAGAATCAATTGCTCTCGTTTAATTTCAGCAACAGGTTTGCTGATATTA
TCCAACTGGGAAACTTTCAGAAATGAGGGCACTATTATATCATTTGACAGTTTAGAATGG
TGTCTGTTCTCAGTAGTAATTTACAGTTTTATAAGCATTTCAATTGCAAAACTGGGAACT
ACGAATTGGTTTGCTAATGTGATTACATTATCTATTTCTTTAGGGCTGGCAATCTCTTCT
AAATTTATTGGAATTGTCACTTGGGCCTTCGTAATTCTTTCTTTTGTACGTCAATTTGAT
AGACTGATAAGCGACGTTAAAGTTACGACCATCCAAATAATAAAATTTGTCATTCTCTGT
CTATTATTCGTTTTGATTATCCCTGGTTCCATCTTCATAATAAGTTATTCGAACTTACTT
TCGAATTTTAAGACAGACACGCCACAATTTTCAAAATATATGAGCACATATTTCAAGTCC
TATTTAAGAGGCCCTCAAGTACAACCGAGTCGATTGTACTATGGATCAACGATCACATTA
CGTCATTTAGATTCTATGGTCGGATATCTTGCTTCTCACGATATTTCGTATCCATCAGAT
GTTGACGAACAGTTAGTAGCGTTATCATTTGAAGAATTCGCGGCAGACAATGAATGGTTA
ATAGAACATCCTACATTAAATTTGAGTTTTTCTGAGGTATACCATGCTGATCAATTGATA
CCTGTAGAATTTGGTCAAAGTATAAAACTAAGACACAAATCTACTGGAAAATTATTGAGA
GCCAGCACTGCTAAACCTCCCATCAGCGAGCAGGACTATGACTTTCAAATTTCATGCACG
AAAGATTCAAACTACGAAGGAGGAATGGATGAGAGATGGGATGTTCTCCTGATTAAAGAT
GAAATCAACAATGATAAAAAGGATAACGCAGATGATAAATACATTAAACCGCTTCAATCA
GAGATACGCTTTTACAATAACGGCCAGAGATGTGGGCTATTGGGCCATGATCTTCGGTTA
CCTGAATGGGGCCGCTTTGAGCAAGAAGTCCTATGTATGGAGTACCCAGTAATACCAAGA
ACCACTTTTCTAATAGACTCAGTACAACTACCAGTCGATTTCCAAGTCCCAATGATAGAA
TATTATATCGGCAAAATAAGTTCTTCAGCAGAATTCAATCATACCTTATCTTGGTCACAA
TTTCTTTATCTTTTCAAAGAATATATTTTCAAACAATACAAGTACAATTACTATATTAAA
TACGGTAAAAATAAGGTCACTTTTGAAGATGCGTTCGCCGTGGAAAAATGGCCAATTACG
TTAGACACAGACTCTCCAGTTTGGTTTAATTTTGCATGGTATGGATCCTTACTCTCGATG
ATCATTTTCATGTGCGTGCAATGTAAGAGAATGATATCTTGGAATCCGTGGACAACTGCT
GAACCTTCCTTTTCTATCAAATGGGAGGTCTACAATGAATTTGGCTGGGAGTGCATTGTC
GGTTGGTTTTTACATTTTTACATCTTCACAATGAGTCCACACTTCAACTTGGGGAAAAAA
CTGTACTTCCAAAGTTTTTTCTTTAGTGTATTGTGTCTTTTAGAATCGTTAGATTGCCTT
GCAAAGTAA |
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| Protein Properties |
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| Pfam Domain Function | |
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| Protein Residues | 662 |
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| Protein Molecular Weight | 77568.79688 |
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| Protein Theoretical pI | 6.78 |
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| Signalling Regions | |
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| Transmembrane Regions | - 27-47
- 160-180
- 196-216
- 236-256
- 483-503
- 566-586
- 618-638
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| Protein Sequence | >Probable dolichyl-phosphate-mannose--protein mannosyltransferase 7
MKDLRLQGPYRKYIPYNIFQQCGIGHLKTLDYIFAFLIVITNFTLIWKSHSSSFWNRPWD
NNSEQELSQLIQFYLDKAFYIHELPPFTIQFYSIIRRLKIAENLRYVSLFLNSSTLGFLF
LITRRINCSRLISATGLLILSNWETFRNEGTIISFDSLEWCLFSVVIYSFISISIAKLGT
TNWFANVITLSISLGLAISSKFIGIVTWAFVILSFVRQFDRLISDVKVTTIQIIKFVILC
LLFVLIIPGSIFIISYSNLLSNFKTDTPQFSKYMSTYFKSYLRGPQVQPSRLYYGSTITL
RHLDSMVGYLASHDISYPSDVDEQLVALSFEEFAADNEWLIEHPTLNLSFSEVYHADQLI
PVEFGQSIKLRHKSTGKLLRASTAKPPISEQDYDFQISCTKDSNYEGGMDERWDVLLIKD
EINNDKKDNADDKYIKPLQSEIRFYNNGQRCGLLGHDLRLPEWGRFEQEVLCMEYPVIPR
TTFLIDSVQLPVDFQVPMIEYYIGKISSSAEFNHTLSWSQFLYLFKEYIFKQYKYNYYIK
YGKNKVTFEDAFAVEKWPITLDTDSPVWFNFAWYGSLLSMIIFMCVQCKRMISWNPWTTA
EPSFSIKWEVYNEFGWECIVGWFLHFYIFTMSPHFNLGKKLYFQSFFFSVLCLLESLDCL
AK |
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| References |
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| External Links | |
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| General Reference | - Jacq, C., Alt-Morbe, J., Andre, B., Arnold, W., Bahr, A., Ballesta, J. P., Bargues, M., Baron, L., Becker, A., Biteau, N., Blocker, H., Blugeon, C., Boskovic, J., Brandt, P., Bruckner, M., Buitrago, M. J., Coster, F., Delaveau, T., del Rey, F., Dujon, B., Eide, L. G., Garcia-Cantalejo, J. M., Goffeau, A., Gomez-Peris, A., Zaccaria, P., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome IV." Nature 387:75-78.9169867
- Kim, H., Melen, K., Osterberg, M., von Heijne, G. (2006). "A global topology map of the Saccharomyces cerevisiae membrane proteome." Proc Natl Acad Sci U S A 103:11142-11147.16847258
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