Probable dolichyl-phosphate-mannose--protein mannosyltransferase 7 (Q06644)

Identification
NameProbable dolichyl-phosphate-mannose--protein mannosyltransferase 7
SynonymsNot Available
Gene NamePMT7
Enzyme Class
Biological Properties
General FunctionInvolved in mannosyltransferase activity
Specific FunctionTransfers mannose from Dol-P-mannose to Ser or Thr residues on proteins
Cellular LocationEndoplasmic reticulum membrane; Multi-pass membrane protein
SMPDB PathwaysNot Available
KEGG Pathways
O-Mannosyl glycan biosynthesisec00514 Map00514
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
YMDB00937dolichyl D-mannosyl phosphateShow
GO Classification
Component
cell part
membrane
Function
catalytic activity
transferase activity
transferase activity, transferring glycosyl groups
transferase activity, transferring hexosyl groups
mannosyltransferase activity
Process
metabolic process
macromolecule metabolic process
macromolecule modification
protein modification process
protein amino acid glycosylation
protein amino acid O-linked glycosylation
Gene Properties
Chromosome LocationNot Available
LocusPMT7
Gene Sequence>1989 bp ATGAAGGACTTGAGATTACAGGGGCCCTACAGAAAGTACATTCCCTATAATATTTTCCAA CAATGTGGAATTGGTCACTTAAAGACGCTTGATTATATTTTCGCGTTTTTGATTGTTATT ACCAATTTCACATTAATATGGAAATCGCACTCTTCTTCATTCTGGAACCGACCATGGGAC AATAATAGTGAACAAGAACTTTCCCAATTAATTCAGTTTTACCTAGACAAGGCTTTTTAC ATCCATGAATTGCCACCATTTACAATACAGTTCTACTCCATTATTCGAAGATTAAAGATC GCAGAAAATTTAAGATACGTTTCTTTGTTTTTGAATTCATCGACTTTAGGTTTTCTTTTC CTGATAACAAGGAGAATCAATTGCTCTCGTTTAATTTCAGCAACAGGTTTGCTGATATTA TCCAACTGGGAAACTTTCAGAAATGAGGGCACTATTATATCATTTGACAGTTTAGAATGG TGTCTGTTCTCAGTAGTAATTTACAGTTTTATAAGCATTTCAATTGCAAAACTGGGAACT ACGAATTGGTTTGCTAATGTGATTACATTATCTATTTCTTTAGGGCTGGCAATCTCTTCT AAATTTATTGGAATTGTCACTTGGGCCTTCGTAATTCTTTCTTTTGTACGTCAATTTGAT AGACTGATAAGCGACGTTAAAGTTACGACCATCCAAATAATAAAATTTGTCATTCTCTGT CTATTATTCGTTTTGATTATCCCTGGTTCCATCTTCATAATAAGTTATTCGAACTTACTT TCGAATTTTAAGACAGACACGCCACAATTTTCAAAATATATGAGCACATATTTCAAGTCC TATTTAAGAGGCCCTCAAGTACAACCGAGTCGATTGTACTATGGATCAACGATCACATTA CGTCATTTAGATTCTATGGTCGGATATCTTGCTTCTCACGATATTTCGTATCCATCAGAT GTTGACGAACAGTTAGTAGCGTTATCATTTGAAGAATTCGCGGCAGACAATGAATGGTTA ATAGAACATCCTACATTAAATTTGAGTTTTTCTGAGGTATACCATGCTGATCAATTGATA CCTGTAGAATTTGGTCAAAGTATAAAACTAAGACACAAATCTACTGGAAAATTATTGAGA GCCAGCACTGCTAAACCTCCCATCAGCGAGCAGGACTATGACTTTCAAATTTCATGCACG AAAGATTCAAACTACGAAGGAGGAATGGATGAGAGATGGGATGTTCTCCTGATTAAAGAT GAAATCAACAATGATAAAAAGGATAACGCAGATGATAAATACATTAAACCGCTTCAATCA GAGATACGCTTTTACAATAACGGCCAGAGATGTGGGCTATTGGGCCATGATCTTCGGTTA CCTGAATGGGGCCGCTTTGAGCAAGAAGTCCTATGTATGGAGTACCCAGTAATACCAAGA ACCACTTTTCTAATAGACTCAGTACAACTACCAGTCGATTTCCAAGTCCCAATGATAGAA TATTATATCGGCAAAATAAGTTCTTCAGCAGAATTCAATCATACCTTATCTTGGTCACAA TTTCTTTATCTTTTCAAAGAATATATTTTCAAACAATACAAGTACAATTACTATATTAAA TACGGTAAAAATAAGGTCACTTTTGAAGATGCGTTCGCCGTGGAAAAATGGCCAATTACG TTAGACACAGACTCTCCAGTTTGGTTTAATTTTGCATGGTATGGATCCTTACTCTCGATG ATCATTTTCATGTGCGTGCAATGTAAGAGAATGATATCTTGGAATCCGTGGACAACTGCT GAACCTTCCTTTTCTATCAAATGGGAGGTCTACAATGAATTTGGCTGGGAGTGCATTGTC GGTTGGTTTTTACATTTTTACATCTTCACAATGAGTCCACACTTCAACTTGGGGAAAAAA CTGTACTTCCAAAGTTTTTTCTTTAGTGTATTGTGTCTTTTAGAATCGTTAGATTGCCTT GCAAAGTAA
Protein Properties
Pfam Domain Function
Protein Residues662
Protein Molecular Weight77568.79688
Protein Theoretical pI6.78
Signalling Regions
  • None
Transmembrane Regions
  • 27-47
  • 160-180
  • 196-216
  • 236-256
  • 483-503
  • 566-586
  • 618-638
Protein Sequence>Probable dolichyl-phosphate-mannose--protein mannosyltransferase 7 MKDLRLQGPYRKYIPYNIFQQCGIGHLKTLDYIFAFLIVITNFTLIWKSHSSSFWNRPWD NNSEQELSQLIQFYLDKAFYIHELPPFTIQFYSIIRRLKIAENLRYVSLFLNSSTLGFLF LITRRINCSRLISATGLLILSNWETFRNEGTIISFDSLEWCLFSVVIYSFISISIAKLGT TNWFANVITLSISLGLAISSKFIGIVTWAFVILSFVRQFDRLISDVKVTTIQIIKFVILC LLFVLIIPGSIFIISYSNLLSNFKTDTPQFSKYMSTYFKSYLRGPQVQPSRLYYGSTITL RHLDSMVGYLASHDISYPSDVDEQLVALSFEEFAADNEWLIEHPTLNLSFSEVYHADQLI PVEFGQSIKLRHKSTGKLLRASTAKPPISEQDYDFQISCTKDSNYEGGMDERWDVLLIKD EINNDKKDNADDKYIKPLQSEIRFYNNGQRCGLLGHDLRLPEWGRFEQEVLCMEYPVIPR TTFLIDSVQLPVDFQVPMIEYYIGKISSSAEFNHTLSWSQFLYLFKEYIFKQYKYNYYIK YGKNKVTFEDAFAVEKWPITLDTDSPVWFNFAWYGSLLSMIIFMCVQCKRMISWNPWTTA EPSFSIKWEVYNEFGWECIVGWFLHFYIFTMSPHFNLGKKLYFQSFFFSVLCLLESLDCL AK
References
External Links
ResourceLink
Saccharomyces Genome Database PMT7
Uniprot IDQ06644
Uniprot NamePMT7_YEAST
GenBank Gene IDU28374
Genebank Protein ID849211
General Reference
  • Jacq, C., Alt-Morbe, J., Andre, B., Arnold, W., Bahr, A., Ballesta, J. P., Bargues, M., Baron, L., Becker, A., Biteau, N., Blocker, H., Blugeon, C., Boskovic, J., Brandt, P., Bruckner, M., Buitrago, M. J., Coster, F., Delaveau, T., del Rey, F., Dujon, B., Eide, L. G., Garcia-Cantalejo, J. M., Goffeau, A., Gomez-Peris, A., Zaccaria, P., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome IV." Nature 387:75-78.9169867
  • Kim, H., Melen, K., Osterberg, M., von Heijne, G. (2006). "A global topology map of the Saccharomyces cerevisiae membrane proteome." Proc Natl Acad Sci U S A 103:11142-11147.16847258