Peroxiredoxin TSA2 (Q04120)

Identification
NamePeroxiredoxin TSA2
Synonyms
  • Cytoplasmic thiol peroxidase 2
  • cTPx 2
  • Thiol-specific antioxidant protein 2
  • Thioredoxin peroxidase 2
Gene NameTSA2
Enzyme Class
Biological Properties
General FunctionPosttranslational modification, protein turnover, chaperones
Specific FunctionReduces peroxides. May play an important role in eliminating peroxides generated during metabolism
Cellular LocationCytoplasm
SMPDB PathwaysNot Available
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
peroxiredoxin activity
antioxidant activity
catalytic activity
oxidoreductase activity
Process
cellular process
cellular homeostasis
cell redox homeostasis
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>591 bp ATGGTAGCAGAAGTTCAAAAACAAGCCCCACCATTTAAGAAAACCGCCGTAGTCGACGGT ATCTTCGAGGAAATTTCACTGGAAAAGTATAAAGGTAAGTACGTTGTTCTAGCTTTTGTC CCATTGGCTTTTTCATTTGTCTGTCCAACTGAGATTGTTGCGTTTTCCGATGCCGCCAAG AAATTCGAAGATCAGGGCGCCCAAGTTTTATTTGCCTCCACCGACTCTGAATATTCCTTA CTGGCATGGACCAACCTTCCCAGAAAAGACGGTGGATTAGGTCCAGTTAAAGTTCCTTTG CTTGCTGATAAGAATCATTCCTTATCCAGAGACTATGGCGTTTTGATTGAAAAAGAAGGT ATAGCTTTAAGAGGTTTGTTCATAATCGACCCGAAGGGAATCATTAGACATATCACTATC AATGATTTATCTGTTGGCAGAAACGTCAATGAAGCTTTGAGATTAGTCGAAGGTTTCCAG TGGACTGACAAAAATGGTACAGTTTTGCCATGCAACTGGACCCCAGGAGCCGCCACCATC AAACCTGACGTTAAAGATTCCAAGGAGTATTTCAAAAATGCCAATAATTAA
Protein Properties
Pfam Domain Function
Protein Residues196
Protein Molecular Weight21614.69922
Protein Theoretical pI7.42
Signalling Regions
  • None
Transmembrane Regions
  • None
Protein Sequence>Peroxiredoxin TSA2 MVAEVQKQAPPFKKTAVVDGIFEEISLEKYKGKYVVLAFVPLAFSFVCPTEIVAFSDAAK KFEDQGAQVLFASTDSEYSLLAWTNLPRKDGGLGPVKVPLLADKNHSLSRDYGVLIEKEG IALRGLFIIDPKGIIRHITINDLSVGRNVNEALRLVEGFQWTDKNGTVLPCNWTPGAATI KPDVKDSKEYFKNANN
References
External Links
ResourceLink
Saccharomyces Genome Database TSA2
Uniprot IDQ04120
Uniprot NameTSA2_YEAST
GenBank Gene IDU33007
Genebank Protein ID927720
General Reference
  • Jacq, C., Alt-Morbe, J., Andre, B., Arnold, W., Bahr, A., Ballesta, J. P., Bargues, M., Baron, L., Becker, A., Biteau, N., Blocker, H., Blugeon, C., Boskovic, J., Brandt, P., Bruckner, M., Buitrago, M. J., Coster, F., Delaveau, T., del Rey, F., Dujon, B., Eide, L. G., Garcia-Cantalejo, J. M., Goffeau, A., Gomez-Peris, A., Zaccaria, P., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome IV." Nature 387:75-78.9169867
  • Park, S. G., Cha, M. K., Jeong, W., Kim, I. H. (2000). "Distinct physiological functions of thiol peroxidase isoenzymes in Saccharomyces cerevisiae." J Biol Chem 275:5723-5732.10681558
  • Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106