Phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI19 (Q04082)

Identification
NamePhosphatidylinositol N-acetylglucosaminyltransferase subunit GPI19
SynonymsNot Available
Gene NameGPI19
Enzyme Class
Biological Properties
General FunctionInvolved in phosphatidylinositol N-acetylglucosaminyltr
Specific FunctionPart of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. Involved in cell wall biosynthesis
Cellular LocationEndoplasmic reticulum membrane; Multi-pass membrane protein (Potential)
SMPDB PathwaysNot Available
KEGG Pathways
Glycosylphosphatidylinositol(GPI)-anchor biosynthesisec00563 Map00563
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
YMDB002301-Phosphatidyl-D-myo-inositolShow
YMDB00277Uridine diphosphate-N-acetylglucosamineShow
YMDB00307Uridine 5'-diphosphateShow
GO ClassificationNot Available
Gene Properties
Chromosome Locationchromosome 4
LocusYDR437W
Gene Sequence>423 bp ATGTATACAAAAGAGTACTACTGGTTTTCACAATATATGATAATAACAAGCACTTTGGTG CTCACCATAATATGGTCCATCTTACCATCATCGCTGGGTGAGGCTGCACCAAAGCAGTTT ATCAACACGCTATTGGACATCTTCCCACAAAGAAGATGGATTATTACCTTGGAGAGCATA ATGCTGATGGGCATGCTATGCACATACATCGGCCTTCTGATGTACAATGAAGATACATTA ACACCGCCGCTAGATTCTCTATCTACAGTAACGGATGCCGGTGGTCAACTTGTAATAGAG GACGACCCGGACGTATTCGTTAAGAAATGGGCCTTTAAAGAAACAAGTGGTATTTACGAT CTGTCTCTGATGGATGCCTGCCAACTTCTCTACCTATATGATAACGACCATACCAGCACA TAG
Protein Properties
Pfam Domain Function
Protein Residues140
Protein Molecular Weight16089.40039
Protein Theoretical pI3.95
Signalling Regions
  • None
Transmembrane Regions
  • 13-33
  • 53-73
Protein Sequence>Phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI19 MYTKEYYWFSQYMIITSTLVLTIIWSILPSSLGEAAPKQFINTLLDIFPQRRWIITLESI MLMGMLCTYIGLLMYNEDTLTPPLDSLSTVTDAGGQLVIEDDPDVFVKKWAFKETSGIYD LSLMDACQLLYLYDNDHTST
References
External Links
ResourceLink
Saccharomyces Genome Database GPI19
Uniprot IDQ04082
Uniprot NameGPI19_YEAST
GenBank Gene IDU33007
Genebank Protein ID927688
General Reference
  • Jacq, C., Alt-Morbe, J., Andre, B., Arnold, W., Bahr, A., Ballesta, J. P., Bargues, M., Baron, L., Becker, A., Biteau, N., Blocker, H., Blugeon, C., Boskovic, J., Brandt, P., Bruckner, M., Buitrago, M. J., Coster, F., Delaveau, T., del Rey, F., Dujon, B., Eide, L. G., Garcia-Cantalejo, J. M., Goffeau, A., Gomez-Peris, A., Zaccaria, P., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome IV." Nature 387:75-78.9169867
  • Huh, W. K., Falvo, J. V., Gerke, L. C., Carroll, A. S., Howson, R. W., Weissman, J. S., O'Shea, E. K. (2003). "Global analysis of protein localization in budding yeast." Nature 425:686-691.14562095
  • Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106
  • Newman, H. A., Romeo, M. J., Lewis, S. E., Yan, B. C., Orlean, P., Levin, D. E. (2005). "Gpi19, the Saccharomyces cerevisiae homologue of mammalian PIG-P, is a subunit of the initial enzyme for glycosylphosphatidylinositol anchor biosynthesis." Eukaryot Cell 4:1801-1807.16278447