Serine/threonine-protein kinase PKH1 (Q03407)

Identification
NameSerine/threonine-protein kinase PKH1
Synonyms
  • 3-phosphoinositide-dependent protein kinase 1
Gene NamePKH1
Enzyme ClassNot Available
Biological Properties
General Functionregulation of nuclear-transcribed mRNA poly(A) tail shortening
Specific FunctionActivates YPK1 by phosphorylating of a threonine residue.
Cellular LocationNot Available
SMPDB Pathways
Stress-activated signalling pathways: cell wall stress test 1PW007861 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
late endosome to vacuole transport via multivesicular body sorting pathway
ATP binding
cytosol
protein serine/threonine kinase activity
peptidyl-serine phosphorylation
MAPK cascade involved in cell wall organization or biogenesis
protein phosphorylation
cell cortex
endocytosis
cytoplasmic mRNA processing body assembly
regulation of nuclear-transcribed mRNA poly(A) tail shortening
protein kinase activity
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>2301 bp ATGGGAAATAGGTCTTTGACAGAGGCAGACCACGCCCTGCTGTCCAAGCCCTTGGTACCG ACATCTGCGGAACATACACAAACGCAAGAGTATCCTCGTCCTTTCGTAGATGGCAGCAAT TCTCAGAGCGGGTCTGAACTACAGGCTTCTCCACAAGGTCAGTTTGGAGAAAAGGCATTG ACTAGTACTAATCGCTTCATTCCCCTGGCAAATGATGACCCGGGTATGCAGCACGAGATG GGTCTTGATCCCTCAATGAGGCGTAGAAGAGAAGAATGGGCAGAACGTGGTGCGGCAAAA ATCGTCAAAGATGTTGTCGACCCAGCTACGGGGGAGTTAACTAAGCATGTTGTCAAGATG GGAATAAAGGACTTCAAGTTTGGAGAGCAACTCGGGGATGGATCATATTCTAGTGTTGTT CTGGCTACCGCCCGTGATTCGGGCAAGAAATATGCAGTAAAAGTGTTGAGTAAAGAATAT CTGATCCGTCAAAAAAAAGTTAAATACGTCACAGTGGAGAAATTGGCTTTGCAGAAGCTG AATGGCACCAAGGGCATATTCAAGCTTTTCTTCACTTTCCAGGACGAGGCAAGCTTGTAT TTCCTTCTAGAATATGCCCCCCACGGTGATTTCTTGGGCTTGATTAAGAAATATGGATCT TTAAACGAGACATGTGCACGCTATTATGCGTCGCAGATCATCGATGCCGTTGACTCCTTG CATAATATCGGCATTATTCACAGGGATATCAAGCCCGAAAACATATTGCTCGACAAAAAT ATGAAAGTGAAGTTGACGGATTTTGGTACAGCCAAAATTTTACCGGAGGAACCTTCGAAC ACCGCAGATGGCAAGCCTTATTTCGATTTGTATGCTAAGTCGAAATCATTTGTTGGTACC GCAGAATATGTTTCTCCTGAGCTACTGAATGATAATTATACAGATTCCCGTTGTGACATT TGGGCATTTGGTTGCATATTGTACCAAATGCTTGCGGGAAAACCGCCTTTTAAAGCTGCC AATGAATATTTGACATTCCAAAAAGTAATGAAGATTCAATATGCGTTTACTGCAGGTTTT CCGCAAATAGTAAAAGATTTAGTTAAAAAACTATTAGTTAGGGATCCAAATGATAGATTG ACCATAAAGCAGATCAAAGCACACCTCTTTTTCCATGAAGTCAACTTTGAAGATGGTTCT GTTTGGGATGATAATCCACCGGAGATACAGCCATATAAAATAAATGCAGAGGCGATGAAG CCCCTGCAAAAGGTTTCTGAATCTGATACCACTGTCAAAATGGCCAACCTTCAGCTGGCT GGTAATGGACATGCAGATACTCCCCTGCAAGCACCAGCAGCGACCTCTCAAGAGCATTCT GTGATCAGTATGACTGCAGCAACCGCCGCATTCAATAAAGATTATACAAGTCAACCCAAA TTGGGGAGCAAGTCAAGCACATCTGTTAGATCTGCCTCCAACAACACAGATCGCGAGGTA ATTCAAAAGAAGGTTTCAAAAAATCGCGCATCTGTATCATCTCCTTCAATTTCTACTACA TCACGGGGGAAAGATAATAGAAGTCGCTCTTCTGACGCCTTCTGGTCACGCTACTTGCAA AATATGGATGAACGTGTCTTGTTGATGAAGGAGGTAGCGCTTTCCACACGAAACTTAGAG GACTCACCTGTAGGTCTTGAGAACGTGGCTCTGGACTACAAGAACCCTCTTGATATCGAG CCTCCTACTGATAGTGCAGGCAAATTTTACAAGAAAATGTTTCTAATAACAAACCTAGGC AGAGCACTTGTTTTTGTCAAGAGAAGAAGTCTCAGCATGTGGGAAGAACAGGAATTTGAA TTGCAATTCGAACTAGAGTTGAATGACGTTGAGAAGATACGCTTTATAAGTGATCAAGTC CTTGAAATTGACGGTTCCAGGACGATTTTCATAGGATGCAAAGAGAGAGCAGTTTTAATG AAACTATGGAAATTAATACATAATGGAATGACCGCCAAACCTAAAGTAGTATCGCCGAAG TCGGACCATAAAATGTTTGATAAGTTCATTCTTCAAAAAAGACAGAATACAAAAAAAAAG AATCAAGCTCCTCCCGTACCTCAATCGAATAGGCTAATAAATGGTTTACCGGACCGTTGC ATCTTAAAGACACCCGAAGAAGGCGCACTTCACACAAAACGTCCCACTTCGTTGCAGACC CGATCGTCATCTAATTACTCAAAATTGCTGGCAAGATCGACACAAATGCGGAAAAACATG ACACGGACAGATGAAAAATGA
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues766
Protein Molecular Weight86251.785
Protein Theoretical pINot Available
Signalling RegionsNot Available
Transmembrane RegionsNot Available
Protein Sequence>Serine/threonine-protein kinase PKH1 MGNRSLTEADHALLSKPLVPTSAEHTQTQEYPRPFVDGSNSQSGSELQASPQGQFGEKAL TSTNRFIPLANDDPGMQHEMGLDPSMRRRREEWAERGAAKIVKDVVDPATGELTKHVVKM GIKDFKFGEQLGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKVKYVTVEKLALQKL NGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVDSL HNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGT AEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVMKIQYAFTAGF PQIVKDLVKKLLVRDPNDRLTIKQIKAHLFFHEVNFEDGSVWDDNPPEIQPYKINAEAMK PLQKVSESDTTVKMANLQLAGNGHADTPLQAPAATSQEHSVISMTAATAAFNKDYTSQPK LGSKSSTSVRSASNNTDREVIQKKVSKNRASVSSPSISTTSRGKDNRSRSSDAFWSRYLQ NMDERVLLMKEVALSTRNLEDSPVGLENVALDYKNPLDIEPPTDSAGKFYKKMFLITNLG RALVFVKRRSLSMWEEQEFELQFELELNDVEKIRFISDQVLEIDGSRTIFIGCKERAVLM KLWKLIHNGMTAKPKVVSPKSDHKMFDKFILQKRQNTKKKNQAPPVPQSNRLINGLPDRC ILKTPEEGALHTKRPTSLQTRSSSNYSKLLARSTQMRKNMTRTDEK
References
External Links
ResourceLink
Saccharomyces Genome Database PKH1
Uniprot IDQ03407
Uniprot NamePKH1
General ReferenceNot Available