Down-regulator of invasive growth 2 (Q03373)
| Identification | |||||||||
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| Name | Down-regulator of invasive growth 2 | ||||||||
| Synonyms |
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| Gene Name | DIG2 | ||||||||
| Enzyme Class | Not Available | ||||||||
| Biological Properties | |||||||||
| General Function | negative regulation of transcription from RNA polymerase II promoter by pheromones | ||||||||
| Specific Function | DIG2 and DIG1 are negative regulators of the filamentation and pheromone induced mating program. DIG1 and DIG2 inhibit the transcriptional activity of STE12 by direct protein-protein interaction. DIG2 binds to the DNA binding domain (DBD) of STE12 and thus inhibits transcription when overexpressed. | ||||||||
| Cellular Location | Not Available | ||||||||
| SMPDB Pathways |
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| KEGG Pathways | Not Available | ||||||||
| SMPDB Reactions | Not Available | ||||||||
| KEGG Reactions | Not Available | ||||||||
| Metabolites |
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| GO Classification |
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| Gene Properties | |||||||||
| Chromosome Location | Not Available | ||||||||
| Locus | |||||||||
| Gene Sequence | >972 bp ATGAATAAAGAAGAGCAAGAAGACCCACAGCAAGAGCAAATATCAACTGTTCAGGAAAAT GATCCCAGGAATTTGCAGCAACTGGGAATGCTGTTAGTATCTCCAGGGCTTGATGAAGAC AGATTGAGTGAGAAAATGATTTCGAAGATCAAAAAATCCAGGGATATCGAAAAAAATCAA AAATTGCTCATATCTAGGCTGTCGCAAAAAGAGGAAGATCATAGTGGTAAGCCTCCTACC ATTACGACTTCTCCAGCAGAGAAAACCGTACCCTTTAAGTCGCTGAATCATTCTTTAAAG AGGAAAAGGGTACCTCCAGCGCTAAATTTTTCCGATATACAAGCATCTTCTCATTTGCAT GGATCTAAAAGTGCTCCACCAAACATAACAAGATTTCCGCAGCACAAAAATAGCCTTAGG GTCAGATATATGGGTAGGATGGCTCCTACGAATCAAGATTATCATCCTTCAGTGGCCAAT TCATATATGACAGCAACCTACCCTTATCCATATACTGGACTGCCACCAGTACCATGCTAC CCATATTCTTCAACTCCAACACAAACGCACGCATACGAAGGCTATTATTCCCCGATGTAT CCCGGCCCCTTGTATAATAATGGTATAATACCAGCCGACTACCATGCAAAGAGGAAGAAG TTGGCTGGTAGATCACCACACTTGGAAGATTTGACATCGAGAAAAAGAACCTTTGTCTCC AAACACCACAACGGAGACCCAATCATAAGTAAGACTGATGAAGACATTGAATGCTCTGTC ACGAAAAATTCATTAAGTGAGGGCGCTTCACTTAACGACGATGCCGATGATGACAACGAC AAAGAAAGGATCATTATTGGAGAAATCTCTCTGTATGATGATGTTTTCAAATTTGAAGTT CGCGACGACAAAAATGACTATATGAAAGCATGTGAAACAATCTGGACTGAATGGCATAAC TTGAAGAAATGA | ||||||||
| Protein Properties | |||||||||
| Pfam Domain Function | Not Available | ||||||||
| Protein Residues | 323 | ||||||||
| Protein Molecular Weight | 36878.99 | ||||||||
| Protein Theoretical pI | Not Available | ||||||||
| Signalling Regions | Not Available | ||||||||
| Transmembrane Regions | Not Available | ||||||||
| Protein Sequence | >Down-regulator of invasive growth 2 MNKEEQEDPQQEQISTVQENDPRNLQQLGMLLVSPGLDEDRLSEKMISKIKKSRDIEKNQ KLLISRLSQKEEDHSGKPPTITTSPAEKTVPFKSLNHSLKRKRVPPALNFSDIQASSHLH GSKSAPPNITRFPQHKNSLRVRYMGRMAPTNQDYHPSVANSYMTATYPYPYTGLPPVPCY PYSSTPTQTHAYEGYYSPMYPGPLYNNGIIPADYHAKRKKLAGRSPHLEDLTSRKRTFVS KHHNGDPIISKTDEDIECSVTKNSLSEGASLNDDADDDNDKERIIIGEISLYDDVFKFEV RDDKNDYMKACETIWTEWHNLKK | ||||||||
| References | |||||||||
| External Links |
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| General Reference | Not Available | ||||||||