Down-regulator of invasive growth 1 (Q03063)
| Identification | ||||||||||
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| Name | Down-regulator of invasive growth 1 | |||||||||
| Synonyms |
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| Gene Name | DIG1 | |||||||||
| Enzyme Class | Not Available | |||||||||
| Biological Properties | ||||||||||
| General Function | negative regulation of transcription from RNA polymerase II promoter by pheromones | |||||||||
| Specific Function | DIG1 and DIG2 are negative regulators of the filamentation and pheromone induced mating program. DIG1 and DIG2 inhibit the transcriptional activity of STE12 by direct protein-protein interaction. DIG1 colocalizes to promoters with STE12 and redistributes with it during induction of filamentation (by butanol) or mating (by pheromone) to program specific genes, but binding of DIG1 to STE12 is reduced by pheromone treatment. | |||||||||
| Cellular Location | Not Available | |||||||||
| SMPDB Pathways |
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| KEGG Pathways | Not Available | |||||||||
| SMPDB Reactions | Not Available | |||||||||
| KEGG Reactions | Not Available | |||||||||
| Metabolites |
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| GO Classification |
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| Gene Properties | ||||||||||
| Chromosome Location | Not Available | |||||||||
| Locus | ||||||||||
| Gene Sequence | >1359 bp ATGGCCGTATCAGCCCGTTTGAGAACGACTGCCGAGGATACATCCATTGCTAAATCAACA CAAGATCCAATTGGTGATACAGAAATCAGTGTAGCAAATGCTAAGGGCAGCAGCGATAGC AACATTAAGAATTCGCCAGGCGGAAACAGCGTTGGTCAGGAGTCGGAGCTAGAGCATGTC CCTGAGGAGGATGACTCTGGTGACAAGGAAGCAGATCATGAGGATTCTGAGACAGCCACT GCGAAGAAGAGGAAAGCCCAACCATTGAAGAATCCGAAGAAATCATTGAAGAGGGGCAGA GTCCCGGCGCCTTTGAATTTATCGGATAGCAACACTAATACACACGGTGGTAATATTAAG GACGGCAACTTGGCTTCGTCTAACTCTGCACATTTTCCTCCTGTTGCTAATCAAAACGTG AAAAGCGCGCCCGCACAAGTTACTCAGCATTCCAAGTTCCAGCCCCGTGTCCAATACTTG GGAAAGGCCAGTTCTAGACAATCTATACAAGTGAATAATAGCAGCAATAGTTATGGGAAA CCACACATGCCCTCGGCGGGCATCATGAGCGCCATGAACCCTTACATGCCCATGAATCGC TACATAATGTCACCATATTATAATCCGTACGGTATCCCTCCACCTCACATGCTGAACAAG CCCATAATGACACCCTACGTGTCGTATCCATATCCAATGGGACCGCGGACCTCCATTCCT TATGCTATGCAAGGTGGCAACGCTAGGCCCTACGAAGAAAATGAGTATAGTGCTAGCAAT TACAGAAACAAGAGGGTTAACGACTCATATGATTCGCCTTTGAGTGGCACCGCTTCCACT GGGAAAACCAGACGATCCGAGGAAGGCTCAAGAAATTCTAGCGTAGGATCAAGTGCGAAT GCCGGTCCTACGCAACAGCGCGCGGATCTACGCCCAGCAGATATGATACCTGCTGAAGAA TACCACTTTGAACGGGATGCATTACTCTCGGCCAACACGAAAGCCAGAAGCGCAAGCACA AGCACAAGTACAAGCACAAGCACAAACCGGGACAGGAGTTCATGGCATGAGGCAGAACCC AATAAAGACGAAGAAGAGGGTACGGACTTGGCCATCGAGGACGGAGCGGTCCCCACTCCC ACTTTTACTACGTTCCAGCGGACCTCGCAGCCGCAGCAGCAATCACCTAGTCTTCTTCAA GGCGAAATCCGACTCTCATCGCATATTTTTGCCTTCGAGTTCCCCCTGAGCTCTAGCAAT GTAGACAAGAAAATGTTTATGAGCATATGTAATAAAGTATGGAATGAATCAAAGGAGCTG ACAAAAAAATCATCATCACATCACAGAACCGGAAAATAG | |||||||||
| Protein Properties | ||||||||||
| Pfam Domain Function | Not Available | |||||||||
| Protein Residues | 452 | |||||||||
| Protein Molecular Weight | 49355.795 | |||||||||
| Protein Theoretical pI | Not Available | |||||||||
| Signalling Regions | Not Available | |||||||||
| Transmembrane Regions | Not Available | |||||||||
| Protein Sequence | >Down-regulator of invasive growth 1 MAVSARLRTTAEDTSIAKSTQDPIGDTEISVANAKGSSDSNIKNSPGGNSVGQESELEHV PEEDDSGDKEADHEDSETATAKKRKAQPLKNPKKSLKRGRVPAPLNLSDSNTNTHGGNIK DGNLASSNSAHFPPVANQNVKSAPAQVTQHSKFQPRVQYLGKASSRQSIQVNNSSNSYGK PHMPSAGIMSAMNPYMPMNRYIMSPYYNPYGIPPPHMLNKPIMTPYVSYPYPMGPRTSIP YAMQGGNARPYEENEYSASNYRNKRVNDSYDSPLSGTASTGKTRRSEEGSRNSSVGSSAN AGPTQQRADLRPADMIPAEEYHFERDALLSANTKARSASTSTSTSTSTNRDRSSWHEAEP NKDEEEGTDLAIEDGAVPTPTFTTFQRTSQPQQQSPSLLQGEIRLSSHIFAFEFPLSSSN VDKKMFMSICNKVWNESKELTKKSSSHHRTGK | |||||||||
| References | ||||||||||
| External Links |
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| General Reference | Not Available | |||||||||