CRE-binding bZIP protein SKO1 (Q02100)

Identification
NameCRE-binding bZIP protein SKO1
SynonymsNot Available
Gene NameSKO1
Enzyme ClassNot Available
Biological Properties
General Functionpositive regulation of transcription from RNA polymerase II promoter in response to osmotic stress
Specific FunctionBinds to the CRE motif 5'-TGACGTCA-3' and acts as a repressor of transcription of the SUC2 gene and most probably other genes.
Cellular LocationNot Available
SMPDB Pathways
Stress-activated signalling pathways: high osmolarity test 1PW002773 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
RNA polymerase II repressing transcription factor binding
RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
negative regulation of transcription from RNA polymerase II promoter
transcriptional repressor activity, RNA polymerase II transcription factor binding
positive regulation of transcription from RNA polymerase II promoter in response to osmotic stress
mitogen-activated protein kinase binding
cytosol
nucleus
RNA polymerase II core promoter proximal region sequence-specific DNA binding
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>1944 bp ATGTCAAGCGAGGAACGCTCGAGACAACCAAGTACTGTTTCAACTTTCGATTTAGAACCC AATCCTTTTGAACAAAGCTTCGCCTCTTCCAAGAAGGCTTTGTCACTTCCAGGCACGATC TCCCATCCGTCTCTACCAAAAGAGCTTTCACGAAACAATTCTACCTCAACGATAACACAA CATTCCCAACGTTCCACTCATAGTTTGAACAGTATTCCAGAAGAAAATGGGAATTCAACC GTTACAGATAATAGTAATCATAATGACGTAAAAAAAGACTCACCTAGTTTTTTACCAGGC CAACAAAGACCTACTATAATATCTCCGCCTATTCTCACACCTGGTGGGTCGAAAAGATTA CCACCTCTACTCCTTTCTCCCTCTATTTTATATCAGGCAAATTCAACTACGAATCCCAGT CAGAATTCACATTCTGTTTCAGTCTCTAATTCAAACCCTAGTGCAATAGGCGTTTCTTCT ACCTCCGGATCTCTGTATCCAAACAGCTCTTCTCCTTCAGGGACTTCACTTATACGCCAG CCACGAAACTCGAACGTGACCACAAGTAATTCTGGTAACGGCTTCCCCACGAATGATTCA CAAATGCCTGGCTTTTTATTAAACTTGTCCAAATCTGGGTTGACACCTAATGAGTCCAAT ATCAGGACCGGGTTGACACCCGGTATTCTTACGCAATCTTACAATTATCCCGTATTGCCG TCAATTAATAAAAATACTATAACAGGTAGCAAAAATGTCAACAAAAGTGTCACAGTGAAT GGAAGTATTGAAAACCACCCTCATGTTAATATAATGCACCCAACTGTAAATGGTACACCA CTTACGCCGGGATTGAGTTCTCTGCTAAACTTACCATCTACTGGAGTTTTGGCTAATCCA GTATTCAAATCAACACCTACAACAAATACCACAGATGGTACCGTCAACAACAGCATCAGT AATTCCAATTTTTCCCCAAATACTTCAACGAAAGCGGCTGTCAAAATGGATAATCCGGCA GAGTTCAATGCCATCGAGCACTCCGCTCATAATCACAAGGAGAATGAAAATTTAACGACT CAAATTGAGAACAATGACCAGTTCAATAACAAAACACGAAAAAGAAAGAGAAGGATGTCT AGCACAAGTTCTACTTCTAAGGCTTCAAGAAAAAATTCCATATCAAGAAAAAACTCAGCA GTTACGACTGCACCAGCACAAAAAGATGATGTTGAAAATAATAAAATTTCAAACAACGTA ACACTTGATGAGAATGAAGAGCAAGAAAGAAAAAGAAAGGAGTTTTTAGAAAGAAATAGA GTAGCTGCATCTAAATTTAGAAAAAGAAAGAAAGAGTACATCAAGAAAATTGAAAATGAT CTACAATTCTATGAATCTGAATATGACGATCTAACTCAGGTCATTGGGAAGCTATGCGGC ATAATACCCTCAAGCTCCTCGAATTCCCAATTCAATGTGAATGTTTCAACTCCGTCATCA TCATCACCACCATCTACATCTTTAATAGCATTGTTAGAGAGTAGCATTTCAAGGAGTGAT TATTCAAGTGCAATGTCAGTATTATCAAACATGAAGCAATTGATATGTGAAACGAATTTT TACCGAAGGGGAGGCAAAAACCCAAGGGACGACATGGATGGCCAAGAAGACAGCTTCAAT AAGGACACTAACGTTGTCAAAAGCGAAAATGCGGGCTATCCTTCCGTTAATTCAAGACCA ATAATTCTAGATAAAAAATACTCACTGAACTCTGGAGCAAATATCAGCAAAAGTAACACA ACTACTAATAATGTGGGAAATAGTGCACAGAATATAATCAATTCATGCTACTCTGTTACT AATCCATTGGTAATAAATGCAAATTCCGATACCCATGATACTAATAAGCATGATGTACTA TCCACTCTACCTCACAATAATTGA
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues647
Protein Molecular Weight70191.49
Protein Theoretical pINot Available
Signalling RegionsNot Available
Transmembrane RegionsNot Available
Protein Sequence>CRE-binding bZIP protein SKO1 MSSEERSRQPSTVSTFDLEPNPFEQSFASSKKALSLPGTISHPSLPKELSRNNSTSTITQ HSQRSTHSLNSIPEENGNSTVTDNSNHNDVKKDSPSFLPGQQRPTIISPPILTPGGSKRL PPLLLSPSILYQANSTTNPSQNSHSVSVSNSNPSAIGVSSTSGSLYPNSSSPSGTSLIRQ PRNSNVTTSNSGNGFPTNDSQMPGFLLNLSKSGLTPNESNIRTGLTPGILTQSYNYPVLP SINKNTITGSKNVNKSVTVNGSIENHPHVNIMHPTVNGTPLTPGLSSLLNLPSTGVLANP VFKSTPTTNTTDGTVNNSISNSNFSPNTSTKAAVKMDNPAEFNAIEHSAHNHKENENLTT QIENNDQFNNKTRKRKRRMSSTSSTSKASRKNSISRKNSAVTTAPAQKDDVENNKISNNV TLDENEEQERKRKEFLERNRVAASKFRKRKKEYIKKIENDLQFYESEYDDLTQVIGKLCG IIPSSSSNSQFNVNVSTPSSSSPPSTSLIALLESSISRSDYSSAMSVLSNMKQLICETNF YRRGGKNPRDDMDGQEDSFNKDTNVVKSENAGYPSVNSRPIILDKKYSLNSGANISKSNT TTNNVGNSAQNIINSCYSVTNPLVINANSDTHDTNKHDVLSTLPHNN
References
External Links
ResourceLink
Saccharomyces Genome Database SKO1
Uniprot IDQ02100
Uniprot NameSKO1
General ReferenceNot Available