| Identification |
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| Name | Dihydroxyacetone kinase 1 |
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| Synonyms | - DHA kinase 1
- Glycerone kinase 1
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| Gene Name | DAK1 |
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| Enzyme Class | |
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| Biological Properties |
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| General Function | Involved in glycerone kinase activity |
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| Specific Function | ATP + glycerone = ADP + glycerone phosphate |
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| Cellular Location | Not Available |
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| SMPDB Pathways | Not Available |
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| KEGG Pathways | |
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| SMPDB Reactions | Not Available |
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| KEGG Reactions | |
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| Metabolites | | YMDB ID | Name | View |
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| YMDB00018 | Dihydroxyacetone | Show | | YMDB00109 | Adenosine triphosphate | Show | | YMDB00322 | Dihydroxyacetone phosphate | Show | | YMDB00862 | hydron | Show | | YMDB00914 | ADP | Show |
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| GO Classification | | Component |
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| Not Available | | Function |
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| transferase activity, transferring phosphorus-containing groups | | binding | | nucleoside binding | | purine nucleoside binding | | adenyl nucleotide binding | | adenyl ribonucleotide binding | | ATP binding | | kinase activity | | glycerone kinase activity | | catalytic activity | | transferase activity | | Process |
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| metabolic process | | small molecule metabolic process | | alcohol metabolic process | | polyol metabolic process | | alditol metabolic process | | glycerol metabolic process |
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| Gene Properties |
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| Chromosome Location | chromosome 13 |
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| Locus | YML070W |
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| Gene Sequence | >1755 bp
ATGTCCGCTAAATCGTTTGAAGTCACAGATCCAGTCAATTCAAGTCTCAAAGGGTTTGCC
CTTGCTAACCCCTCCATTACGCTGGTCCCTGAAGAAAAAATTCTCTTCAGAAAGACCGAT
TCCGACAAGATCGCATTAATTTCTGGTGGTGGTAGTGGACATGAACCTACACACGCCGGT
TTCATTGGTAAGGGTATGTTGAGTGGCGCCGTGGTTGGCGAAATTTTTGCATCCCCTTCA
ACAAAACAGATTTTAAATGCAATCCGTTTAGTCAATGAAAATGCGTCTGGCGTTTTATTG
ATTGTGAAGAACTACACAGGTGATGTTTTGCATTTTGGTCTGTCCGCTGAGAGAGCAAGA
GCCTTGGGTATTAACTGCCGCGTTGCTGTCATAGGTGATGATGTTGCAGTTGGCAGAGAA
AAGGGTGGTATGGTTGGTAGAAGAGCATTGGCAGGTACCGTTTTGGTTCATAAGATTGTA
GGTGCCTTCGCAGAAGAATATTCTAGTAAGTATGGCTTAGACGGTACAGCTAAAGTGGCT
AAAATTATCAACGACAATTTGGTGACCATTGGATCTTCTTTAGACCATTGTAAAGTTCCT
GGCAGGAAATTCGAAAGTGAATTAAACGAAAAACAAATGGAATTGGGTATGGGTATTCAT
AACGAACCTGGTGTGAAAGTTTTAGACCCTATTCCTTCTACCGAAGACTTGATCTCCAAG
TATATGCTACCAAAACTATTGGATCCAAACGATAAGGATAGAGCTTTTGTAAAGTTTGAT
GAAGATGATGAAGTTGTCTTGTTAGTTAACAATCTCGGCGGTGTTTCTAATTTTGTTATT
AGTTCTATCACTTCCAAAACTACGGATTTCTTAAAGGAAAATTACAACATAACCCCGGTT
CAAACAATTGCTGGCACATTGATGACCTCCTTCAATGGTAATGGGTTCAGTATCACATTA
CTAAACGCCACTAAGGCTACAAAGGCTTTGCAATCTGATTTTGAGGAGATCAAATCAGTA
CTAGACTTGTTGAACGCATTTACGAACGCACCGGGCTGGCCAATTGCAGATTTTGAAAAG
ACTTCTGCCCCATCTGTTAACGATGACTTGTTACATAATGAAGTAACAGCAAAGGCCGTC
GGTACCTATGACTTTGACAAGTTTGCTGAGTGGATGAAGAGTGGTGCTGAACAAGTTATC
AAGAGCGAACCGCACATTACGGAACTAGACAATCAAGTTGGTGATGGTGATTGTGGTTAC
ACTTTAGTGGCAGGAGTTAAAGGCATCACCGAAAACCTTGACAAGCTGTCGAAGGACTCA
TTATCTCAGGCGGTTGCCCAAATTTCAGATTTCATTGAAGGCTCAATGGGAGGTACTTCT
GGTGGTTTATATTCTATTCTTTTGTCGGGTTTTTCACACGGATTAATTCAGGTTTGTAAA
TCAAAGGATGAACCCGTCACTAAGGAAATTGTGGCTAAGTCACTCGGAATTGCATTGGAT
ACTTTATACAAATATACAAAGGCAAGGAAGGGATCATCCACCATGATTGATGCTTTAGAA
CCATTCGTTAAAGAATTTACTGCATCTAAGGATTTCAATAAGGCGGTAAAAGCTGCAGAG
GAAGGTGCTAAATCCACTGCTACATTCGAGGCCAAATTTGGCAGAGCTTCGTATGTCGGC
GATTCATCTCAAGTAGAAGATCCTGGTGCAGTAGGCCTATGTGAGTTTTTGAAGGGGGTT
CAAAGCGCCTTGTAA |
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| Protein Properties |
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| Pfam Domain Function | |
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| Protein Residues | 584 |
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| Protein Molecular Weight | 62206.10156 |
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| Protein Theoretical pI | 5.05 |
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| Signalling Regions | |
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| Transmembrane Regions | |
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| Protein Sequence | >Dihydroxyacetone kinase 1
MSAKSFEVTDPVNSSLKGFALANPSITLVPEEKILFRKTDSDKIALISGGGSGHEPTHAG
FIGKGMLSGAVVGEIFASPSTKQILNAIRLVNENASGVLLIVKNYTGDVLHFGLSAERAR
ALGINCRVAVIGDDVAVGREKGGMVGRRALAGTVLVHKIVGAFAEEYSSKYGLDGTAKVA
KIINDNLVTIGSSLDHCKVPGRKFESELNEKQMELGMGIHNEPGVKVLDPIPSTEDLISK
YMLPKLLDPNDKDRAFVKFDEDDEVVLLVNNLGGVSNFVISSITSKTTDFLKENYNITPV
QTIAGTLMTSFNGNGFSITLLNATKATKALQSDFEEIKSVLDLLNAFTNAPGWPIADFEK
TSAPSVNDDLLHNEVTAKAVGTYDFDKFAEWMKSGAEQVIKSEPHITELDNQVGDGDCGY
TLVAGVKGITENLDKLSKDSLSQAVAQISDFIEGSMGGTSGGLYSILLSGFSHGLIQVCK
SKDEPVTKEIVAKSLGIALDTLYKYTKARKGSSTMIDALEPFVKEFTASKDFNKAVKAAE
EGAKSTATFEAKFGRASYVGDSSQVEDPGAVGLCEFLKGVQSAL |
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| References |
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| External Links | |
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| General Reference | - Bowman, S., Churcher, C., Badcock, K., Brown, D., Chillingworth, T., Connor, R., Dedman, K., Devlin, K., Gentles, S., Hamlin, N., Hunt, S., Jagels, K., Lye, G., Moule, S., Odell, C., Pearson, D., Rajandream, M., Rice, P., Skelton, J., Walsh, S., Whitehead, S., Barrell, B. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII." Nature 387:90-93.9169872
- Norbeck, J., Blomberg, A. (1997). "Metabolic and regulatory changes associated with growth of Saccharomyces cerevisiae in 1.4 M NaCl. Evidence for osmotic induction of glycerol dissimilation via the dihydroxyacetone pathway." J Biol Chem 272:5544-5554.9038161
- Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106
- Smolka, M. B., Albuquerque, C. P., Chen, S. H., Zhou, H. (2007). "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases." Proc Natl Acad Sci U S A 104:10364-10369.17563356
- Albuquerque, C. P., Smolka, M. B., Payne, S. H., Bafna, V., Eng, J., Zhou, H. (2008). "A multidimensional chromatography technology for in-depth phosphoproteome analysis." Mol Cell Proteomics 7:1389-1396.18407956
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