RHO1 GDP-GTP exchange protein 2 (P51862)

Identification
NameRHO1 GDP-GTP exchange protein 2
SynonymsNot Available
Gene NameROM2
Enzyme ClassNot Available
Biological Properties
General Functionsmall GTPase mediated signal transduction
Specific FunctionStimulates the exchange of RHO1 GDP-bound form into GTP-bound form.
Cellular LocationNot Available
SMPDB Pathways
Stress-activated signalling pathways: cell wall stress test 1PW007861 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
negative regulation of cAMP-mediated signaling
cellular bud tip
incipient cellular bud site
mating projection tip
positive regulation of endocytosis
regulation of fungal-type cell wall organization
small GTPase mediated signal transduction
Rho guanyl-nucleotide exchange factor activity
regulation of Rho protein signal transduction
signal transducer activity
establishment of cell polarity
phosphatidylinositol-4,5-bisphosphate binding
activation of GTPase activity
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>4071 bp ATGAGCGAAACCAACGTTGACAGCTTAGGGGACAGAAATGACATATACTCCCAAATATTT GGTGTAGAAAGGAGGCCAGATTCCTTCGCTACTTTTGATAGTGACTCGCACGGAGACATA AGTTCTCAGCTGCTGCCTAATAGAATCGAAAATATCCAGAATCTAAATGTTCTGCTTTCT GAAGACATTGCTAATGACATCATTATTGCCAAGCAGAGGAGACGTTCTGGAGTTGAAGCC GCCATCGATGATTCTGATATACCAAATAACGAAATGAAGGGGAAAAGCTCAAATTACATT TTATCGCAGCAGACTAATATTAAGGAAGTTCCAGATACACAAAGTTTGTCTAGTGCTGAT AATACACCTGTGAGCAGTCCAAAGAAGGCAAGAGATGCCACATCTTCCCATCCCATTGTT CATGCTAAATCGATGTCCCATATATATTCAACGAGTAATAGTGCTAGTAGACAAGCCAAG CACTATAATGACCACCCTTTGCCTCCAATGTCTCCAAGAAATGAAGTTTACCAGAAGAAT AAAAGTACTACAGCTTTTGTGCCTAAGAGGAAACCTTCGCTCCCGCAACTAGCACTTGCT GGTCTTAAGAAGCAGAGCAGTTTTTCCACCGGCAGTGCATCAACCACTCCTACACAGGCT AGAAAATCGCCTTTGCAAGGGTTTGGTTTCTTTTCGAGACCAAGTTCCAAAGACTTGCAC GAACAGCACCAACATCACCAGCATATTCAGCATAATAATATTAACAATCATAATAATAAT AATACTAATAATAATGGCGCACATTATCAAGTGGGTAGTAGTAACAGTAATTACCCTCAA CATTCACATTCTATATCATCTAGATCGATGTCGTTGAACTCATCTACTCTAAAAAATATT GCATCATCTTTTCAATCGAAGACTTCTAACAGCAGGAAAGCTACGCAAAAATATGATATA ACTTCCAACCCATTCTCAGATCCTCATCATCATCATCATCATCATCACTCTTCAAACAGT CACAGTAGCCTAAATAATGTCCACGGGTCTGGAAACTCCTCAAGTGTTATGGGAAGCTCG TCTAATATTGGGTTGGGTCTTAAAACGAGAGTTTCTTCCACCTCATTAGCTTTAAAAAGA TACACTTCGGTTTCAGGAACTTCTCTATCTTCTCCACGTAGAAGTAGTATGACACCTTTG TCGGCATCTAGACCTGTTATGAGCGCTTCATCAAAAAAACCTCAGGTATATCCAGCTTTG TTGTCAAGAGTCGCCACAAAATTTAAAAGTTCGATACAACTCGGGGAACATAAGAAGGAT GGATTAGTTTACCGTGACGCATTTACAGGGCAGCAGGCAGTCGATGTCATCTGTGCTATC ATTAGAACTTCTGATAGAAACTTAGCCTTGTTATTTGGTAGATCACTAGATGCACAAAAG CTGTTCCATGATGTGGTATACGAGCACAGGTTAAGAGATTCACCACATGAAGTTTACGAA TTTACAGATAACTCAAGATTTACAGGAACAGGTTCCACAAACGCCCATGATCCACTGATG CTACTCCCAAACTCATCATCTTTTAATTCCGGGAACCACTCTTATCCGAATTCCGGAATG GTTCCATCAAGTTCAACTTCATCTTTGAATAGTGATCAGGCAACTTTGACAGGGTCGAGG CTACATATGAGTAGTTCATTGTCCCAGCAAAAGAACCCTGCAGCCATTCATAACGTCAAT GGTGTGTTTACATTACTGGCGGAATGCTATTCCCCTACGTGCACAAGAGACGCTTTGTGT TACTCTATTTCGTGTCCAAGACGTCTTGAGCAACAAGCAAGGTTAAATCTGAAACCAAAT GGCGGCCTGAAACGTAATATATCAATGGCATTGGATGATGATGACGAAGAAAAGCCATCT TGGACAAGTTCCGTATCTAAAGAGGATTGGGAAAACTTACCAAAAAAGGAAATAAAAAGA CAAGAGGCTATTTATGAAGTTTATATCACGGAGAAGAACTTTGTAAAATCATTAGAAATT ACAAGAGACACATTCATGAAGACTTTGGCTGAAACAAATATTATTTCAGCAGATATTAGA AAAAATTTCATCAAGCATGTTTTTGCACATATAAACGATATCTATTCAGTGAATAGACGT TTTTTGAAGGCTTTAACTGATAGGCAAAGAAGTTCACCAGTTGTGAGAGGAATTGGGGAC ATTGTTTTAAGATTCATTCCATTTTTTGAACCATTTGTTTCATATGTCGCTTCAAGACCA TATGCGAAGTACTTGATTGAAACCCAAAGATCAGTCAATCCCTATTTTGCTAGATTTGAT GACGATATGATGAGCTCCTCCTTACGTCATGGTATTGATTCGTTTTTATCTCAAGGTGTT TCAAGACCAGGTCGATATATGCTATTGGTCAAAGAAATCATGAAATCTACTGACCCCGAG AAGGACAAAAGTGATTATGAAGATTTAAGCAAAGCCATGGATGCATTAAGGGATTTTATG AAAAGGATTGATCAAGCAAGTGGTGCTGCACAAGATAGACATGATGTAAAATTGTTGAAA CAAAAGATTCTTTTCAAAAACGAATACGTTAATTTAGGATTAAATGACGAAAGGAGAAAA ATTAAACATGAAGGTATACTATCACGGAAGGAGTTGTCAAAATCGGACGGAACAGTTGTT GGTGACATACAATTTTATCTTCTAGATAATATGCTCTTATTTTTAAAGGCCAAAGCAGTT AATAAATGGCACCAGCATAAGGTATTCCAAAGGCCCATTCCATTGCCATTGTTATTTGCA TGTCCAGGTGAAGATATGCCTGCGTTGAGGAAATATATTGGAGACCACCCAGATTGTTCA GGAACTGTAATTCAACCAGAATACAACACGAGTAATCCTAAAAACGCAATAACTTTCTTA TACTACGGTGCCAAGCAGAGATATCAAGTTACATTATATGCTGCGCAATACGCTGGATTG CAAACGCTTTTGGAAAAAATAAAGCAAGGACAAGCAGCTATTATAAGCAAAACGGAGATG TTCAATGTAACGAAAATGAGCGATAGGTTCTTCGATTACACCAACAAAATTAACAGTGTT ACTTCCTGTGATGGGGGTAGAAAACTTCTGATTGCAACGAACTCTGGATTGTATATGAGC AACATTAAAAGACAGCAGAATAAAGATCATAGACATAAAAGCTCTGCTTTTTTTTCAACT CCAATCCAACTAGTACAAAGAAATAATATCACTCAAATTGCTGTATTAGAAGAATTCAAA TCAATCATACTTTTAATTGATAAAAAATTATACAGTTGTCCGCTGTCATTAATCGAAGCA GAAGGTAATGGGACATCTTTCTTCAAAAAGCATCACAAGGAACTGATCAATCATGTGAGT TTCTTCGCAGAAGGAGATTGCAATGGTAAGAGATTAATCGTGACTGCACACAGTTCATCG CATTCAATTAAGTACTTCGAGCATGAACATCCATTATTGGCCGAAAAAAATGGTAGTGGT AGCGGTAACAAAAAAAGTCTCAAGAAAAAAATCACCGAGGTTATTTTTGATTCTGAACCT GTCTCTATTTCATTTCTCAAGGCCAACCTATGCATTGGCTGTAAAAAGGGTTTTCAGATC GTTAGCATTTCACAGAATGCTCATGAATCCTTGTTAGATCCGGCCGATACATCATTAGAG TTTGCACTAAGGGATACTTTGAAACCAATGGCAATCTATCGTGTGGGAAATATGTTTTTG CTGTGTTACACAGAATTTGCCTTCTTTGTCAATAATCAGGGTTGGAGAAAGAAAGAATCG CATATTATTCATTGGGAGGGAGAGCCCCAAAAATTTGCAATTTGGTACCCGTACATCTTG GCATTCGACAGCAACTTCATTGAGATCAGAAAGATTGAAACTGGCGAATTAATTCGTTGC GTCCTTGCTGATAAGATTCGACTTCTACAAACAAGTACTCAAGAAATCCTGTACTGCTAC GAGGATTATCGCGGGTATGATACAGTTGCGTCGTTAGATTTCTGGGGTTAA
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues1356
Protein Molecular Weight152594.615
Protein Theoretical pINot Available
Signalling RegionsNot Available
Transmembrane RegionsNot Available
Protein Sequence>RHO1 GDP-GTP exchange protein 2 MSETNVDSLGDRNDIYSQIFGVERRPDSFATFDSDSHGDISSQLLPNRIENIQNLNVLLS EDIANDIIIAKQRRRSGVEAAIDDSDIPNNEMKGKSSNYILSQQTNIKEVPDTQSLSSAD NTPVSSPKKARDATSSHPIVHAKSMSHIYSTSNSASRQAKHYNDHPLPPMSPRNEVYQKN KSTTAFVPKRKPSLPQLALAGLKKQSSFSTGSASTTPTQARKSPLQGFGFFSRPSSKDLH EQHQHHQHIQHNNINNHNNNNTNNNGAHYQVGSSNSNYPQHSHSISSRSMSLNSSTLKNI ASSFQSKTSNSRKATQKYDITSNPFSDPHHHHHHHHSSNSHSSLNNVHGSGNSSSVMGSS SNIGLGLKTRVSSTSLALKRYTSVSGTSLSSPRRSSMTPLSASRPVMSASSKKPQVYPAL LSRVATKFKSSIQLGEHKKDGLVYRDAFTGQQAVDVICAIIRTSDRNLALLFGRSLDAQK LFHDVVYEHRLRDSPHEVYEFTDNSRFTGTGSTNAHDPLMLLPNSSSFNSGNHSYPNSGM VPSSSTSSLNSDQATLTGSRLHMSSSLSQQKNPAAIHNVNGVFTLLAECYSPTCTRDALC YSISCPRRLEQQARLNLKPNGGLKRNISMALDDDDEEKPSWTSSVSKEDWENLPKKEIKR QEAIYEVYITEKNFVKSLEITRDTFMKTLAETNIISADIRKNFIKHVFAHINDIYSVNRR FLKALTDRQRSSPVVRGIGDIVLRFIPFFEPFVSYVASRPYAKYLIETQRSVNPYFARFD DDMMSSSLRHGIDSFLSQGVSRPGRYMLLVKEIMKSTDPEKDKSDYEDLSKAMDALRDFM KRIDQASGAAQDRHDVKLLKQKILFKNEYVNLGLNDERRKIKHEGILSRKELSKSDGTVV GDIQFYLLDNMLLFLKAKAVNKWHQHKVFQRPIPLPLLFACPGEDMPALRKYIGDHPDCS GTVIQPEYNTSNPKNAITFLYYGAKQRYQVTLYAAQYAGLQTLLEKIKQGQAAIISKTEM FNVTKMSDRFFDYTNKINSVTSCDGGRKLLIATNSGLYMSNIKRQQNKDHRHKSSAFFST PIQLVQRNNITQIAVLEEFKSIILLIDKKLYSCPLSLIEAEGNGTSFFKKHHKELINHVS FFAEGDCNGKRLIVTAHSSSHSIKYFEHEHPLLAEKNGSGSGNKKSLKKKITEVIFDSEP VSISFLKANLCIGCKKGFQIVSISQNAHESLLDPADTSLEFALRDTLKPMAIYRVGNMFL LCYTEFAFFVNNQGWRKKESHIIHWEGEPQKFAIWYPYILAFDSNFIEIRKIETGELIRC VLADKIRLLQTSTQEILYCYEDYRGYDTVASLDFWG
References
External Links
ResourceLink
Saccharomyces Genome Database ROM2
Uniprot IDP51862
Uniprot NameROM2
General ReferenceNot Available