| Identification |
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| Name | Probable inosine-5'-monophosphate dehydrogenase IMD4 |
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| Synonyms | - IMP dehydrogenase
- IMPD
- IMPDH
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| Gene Name | IMD4 |
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| Enzyme Class | |
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| Biological Properties |
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| General Function | Involved in catalytic activity |
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| Specific Function | Inosine 5'-phosphate + NAD(+) + H(2)O = xanthosine 5'-phosphate + NADH |
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| Cellular Location | Not Available |
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| SMPDB Pathways | Not Available |
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| KEGG Pathways | |
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| SMPDB Reactions | Not Available |
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| KEGG Reactions | Not Available |
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| Metabolites | | YMDB ID | Name | View |
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| YMDB00110 | NAD | Show | | YMDB00143 | NADH | Show | | YMDB00289 | Xanthylic acid | Show | | YMDB00352 | Inosinic acid | Show |
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| GO Classification | | Component |
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| Not Available | | Function |
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| oxidoreductase activity, acting on CH-OH group of donors | | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | | IMP dehydrogenase activity | | catalytic activity | | oxidoreductase activity | | Process |
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| metabolic process | | oxidation reduction |
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| Gene Properties |
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| Chromosome Location | chromosome 13 |
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| Locus | YML056C |
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| Gene Sequence | >1575 bp
ATGAGTGCTGCTCCATTGGATTACAAAAAGGCTTTAGAACATTTGAAGACATACAGTTCC
AAGGACGGTCTTTCTGTCCAGGAATTGATGGACTCCACAACTAGAGGTGGGTTGACCTAC
AATGATTTTTTGGTCTTACCAGGCTTGGTCAATTTCCCATCTTCTGCTGTCAGTTTGCAA
ACCAAATTGACCAAGAAAATCACTTTGAACACTCCTTTTGTCTCTTCTCCTATGGACACA
GTCACTGAAGCTGATATGGCTATTTATATGGCTTTATTGGGTGGTATTGGTTTCATCCAT
CACAACTGTACTCCAAAGGAACAGGCTTCCATGGTCAAGAAAGTTAAAATGTTTGAAAAC
GGTTTCATCAATTCTCCAATAGTAATTTCTCCAACCACCACTGTTGGTGAAGTTAAGGTT
ATGAAGAGAAAGTTTGGTTTCTCTGGCTTCCCAGTTACTGAAGACGGTAAGTGTCCAGGT
AAGTTAGTTGGGTTAGTCACCTCTCGTGATATACAATTCTTAGAAGATGATTCTTTGGTT
GTTTCTGAAGTCATGACTAAAAATCCAGTTACTGGCATCAAGGGTATTACTTTGAAAGAA
GGTAATGAAATCCTAAAACAAACCAAGAAAGGTAAATTGCTTATCGTTGATGATAACGGT
AACCTCGTTTCCATGTTGTCAAGAGCGGATTTGATGAAGAATCAAAACTACCCGTTAGCT
TCTAAATCCGCCACCACCAAGCAATTGCTATGTGGTGCTGCAATTGGTACTATCGAAGCT
GATAAGGAAAGATTAAGACTATTAGTCGAAGCAGGTTTGGATGTTGTTATCTTAGATTCC
TCTCAAGGTAACTCTGTTTTCCAATTGAACATGATCAAATGGATTAAAGAAACTTTCCCA
GATTTGGAAATCATTGCTGGTAACGTTGCCACCAGAGAACAAGCTGCTAACTTGATTGCT
GCCGGTGCCGATGGTTTAAGAATTGGTATGGGTTCTGGGTCTATTTGTATCACTCAAGAA
GTTATGGCTTGTGGTAGACCACAAGGTACAGCTGTCTACAACGTTTGTCAATTTGCTAAC
CAATTTGGCGTTCCATGTATGGCTGATGGTGGTGTCCAAAACATTGGCCACATCACCAAG
GCTTTGGCCCTTGGTTCCTCCACCGTCATGATGGGTGGTATGTTAGCTGGTACTACCGAG
TCACCAGGTGAATACTTCTACAAGGATGGTAAGAGATTGAAGGCTTATCGTGGTATGGGG
TCCATTGACGCCATGCAAAAGACCGGTAACAAGGGTAATGCCTCTACTTCTCGTTATTTC
TCTGAGTCAGACAGTGTCTTGGTTGCACAAGGTGTTTCTGGGGCTGTCGTAGACAAAGGT
TCCATCAAGAAGTTTATTCCATATTTGTACAACGGTTTACAACATTCTTGTCAAGACATT
GGTTGCGAATCTCTAACTTCATTGAAAGAGAATGTTCAAAATGGTGAAGTTAGATTTGAA
TTCAGAACCGCTTCTGCTCAATTAGAAGGTGGTGTCCATAATTTGCACTCCTATGAAAAA
CGTCTATACAATTGA |
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| Protein Properties |
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| Pfam Domain Function | |
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| Protein Residues | 524 |
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| Protein Molecular Weight | 56393.5 |
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| Protein Theoretical pI | 8.29 |
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| Signalling Regions | |
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| Transmembrane Regions | |
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| Protein Sequence | >Probable inosine-5'-monophosphate dehydrogenase IMD4
MSAAPLDYKKALEHLKTYSSKDGLSVQELMDSTTRGGLTYNDFLVLPGLVNFPSSAVSLQ
TKLTKKITLNTPFVSSPMDTVTEADMAIYMALLGGIGFIHHNCTPKEQASMVKKVKMFEN
GFINSPIVISPTTTVGEVKVMKRKFGFSGFPVTEDGKCPGKLVGLVTSRDIQFLEDDSLV
VSEVMTKNPVTGIKGITLKEGNEILKQTKKGKLLIVDDNGNLVSMLSRADLMKNQNYPLA
SKSATTKQLLCGAAIGTIEADKERLRLLVEAGLDVVILDSSQGNSVFQLNMIKWIKETFP
DLEIIAGNVATREQAANLIAAGADGLRIGMGSGSICITQEVMACGRPQGTAVYNVCQFAN
QFGVPCMADGGVQNIGHITKALALGSSTVMMGGMLAGTTESPGEYFYKDGKRLKAYRGMG
SIDAMQKTGNKGNASTSRYFSESDSVLVAQGVSGAVVDKGSIKKFIPYLYNGLQHSCQDI
GCESLTSLKENVQNGEVRFEFRTASAQLEGGVHNLHSYEKRLYN |
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| References |
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| External Links | |
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| General Reference | - Bowman, S., Churcher, C., Badcock, K., Brown, D., Chillingworth, T., Connor, R., Dedman, K., Devlin, K., Gentles, S., Hamlin, N., Hunt, S., Jagels, K., Lye, G., Moule, S., Odell, C., Pearson, D., Rajandream, M., Rice, P., Skelton, J., Walsh, S., Whitehead, S., Barrell, B. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII." Nature 387:90-93.9169872
- Zhang, Z., Dietrich, F. S. (2005). "Mapping of transcription start sites in Saccharomyces cerevisiae using 5' SAGE." Nucleic Acids Res 33:2838-2851.15905473
- Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106
- Albuquerque, C. P., Smolka, M. B., Payne, S. H., Bafna, V., Eng, J., Zhou, H. (2008). "A multidimensional chromatography technology for in-depth phosphoproteome analysis." Mol Cell Proteomics 7:1389-1396.18407956
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