Identification |
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Name | Phosphoserine phosphatase |
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Synonyms | - PSP
- PSPase
- O-phosphoserine phosphohydrolase
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Gene Name | SER2 |
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Enzyme Class | |
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Biological Properties |
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General Function | Involved in catalytic activity |
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Specific Function | O-phospho-L(or D)-serine + H(2)O = L(or D)- serine + phosphate |
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Cellular Location | Cytoplasmic |
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SMPDB Pathways | |
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KEGG Pathways | Glycine, serine and threonine metabolism | ec00260 | | Methane metabolism | ec00680 | |
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SMPDB Reactions | |
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KEGG Reactions | |
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Metabolites | YMDB ID | Name | View |
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YMDB00076 | DL-O-Phosphoserine | Show | YMDB00112 | L-Serine | Show | YMDB00761 | O-Phospho-L-serine | Show | YMDB00890 | water | Show | YMDB00907 | phosphate | Show |
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GO Classification | Component |
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Not Available | Function |
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phosphoserine phosphatase activity | catalytic activity | hydrolase activity | hydrolase activity, acting on ester bonds | phosphoric ester hydrolase activity | phosphatase activity | Process |
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serine family amino acid metabolic process | L-serine metabolic process | L-serine biosynthetic process | metabolic process | cellular metabolic process | cellular amino acid and derivative metabolic process | cellular amino acid metabolic process |
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Gene Properties |
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Chromosome Location | chromosome 7 |
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Locus | YGR208W |
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Gene Sequence | >930 bp
ATGTCAAAGTTTGTTATCACCTGCATAGCTCATGGAGAAAATCTCCCAAAAGAAACCATC
GACCAGATTGCGAAAGAAATTACTGAAAGCTCGGCGAAAGATGTATCAATCAATGGTACC
AAGAAACTATCGGCCAGAGCTACCGATATATTCATTGAAGTCGCAGGATCGATTGTTCAA
AAAGACCTCAAGAATAAGCTGACGAACGTCATTGACAGTCATAATGATGTTGATGTTATT
GTTTCTGTCGACAATGAATATCGTCAAGCCAAAAAGCTCTTTGTCTTTGACATGGATTCA
ACATTAATCTACCAAGAGGTCATCGAATTGATTGCCGCTTATGCTGGTGTTGAAGAACAA
GTGCACGAGATCACAGAAAGAGCCATGAACAATGAACTTGATTTCAAAGAGTCTTTAAGA
GAACGCGTTAAATTATTGCAAGGCCTCCAAGTCGATACACTATATGATGAAATAAAACAA
AAGCTAGAGGTCACCAAGGGTGTGCCAGAACTATGCAAGTTCCTTCACAAAAAAAATTGC
AAGCTCGCTGTTTTAAGCGGTGGTTTTATTCAGTTTGCCGGTTTTATCAAGGATCAGTTA
GGTTTAGATTTTTGTAAGGCAAACTTGTTGGAAGTTGACACTGATGGAAAATTAACCGGT
AAAACACTGGGTCCTATCGTAGACGGACAGTGCAAGAGTGAAACCCTTCTGCAACTATGT
AATGACTACAATGTTCCAGTTGAAGCAAGTTGTATGGTGGGTGACGGTGGTAACGACCTG
CCAGCCATGGCTACCGCCGGGTTTGGGATCGCATGGAACGCCAAGCCAAAGGTGCAGAAA
GCTGCACCTTGTAAGTTGAATACCAAGAGCATGACTGACATTTTATACATTCTTGGTTAC
ACCGATGATGAAATATACAATAGACAATGA |
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Protein Properties |
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Pfam Domain Function | |
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Protein Residues | 309 |
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Protein Molecular Weight | 34207.0 |
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Protein Theoretical pI | 4.83 |
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Signalling Regions | |
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Transmembrane Regions | |
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Protein Sequence | >Phosphoserine phosphatase
MSKFVITCIAHGENLPKETIDQIAKEITESSAKDVSINGTKKLSARATDIFIEVAGSIVQ
KDLKNKLTNVIDSHNDVDVIVSVDNEYRQAKKLFVFDMDSTLIYQEVIELIAAYAGVEEQ
VHEITERAMNNELDFKESLRERVKLLQGLQVDTLYDEIKQKLEVTKGVPELCKFLHKKNC
KLAVLSGGFIQFAGFIKDQLGLDFCKANLLEVDTDGKLTGKTLGPIVDGQCKSETLLQLC
NDYNVPVEASCMVGDGGNDLPAMATAGFGIAWNAKPKVQKAAPCKLNTKSMTDILYILGY
TDDEIYNRQ |
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References |
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External Links | |
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General Reference | - Guerreiro, P., Barreiros, T., Soares, H., Cyrne, L., Maia e Silva, A., Rodrigues-Pousada, C. (1996). "Sequencing of a 17.6 kb segment on the right arm of yeast chromosome VII reveals 12 ORFs, including CCT, ADE3 and TR-I genes, homologues of the yeast PMT and EF1G genes, of the human and bacterial electron-transferring flavoproteins (beta-chain) and of the Escherichia coli phosphoserine phosphohydrolase, and five new ORFs." Yeast 12:273-280.8904340
- Tettelin, H., Agostoni Carbone, M. L., Albermann, K., Albers, M., Arroyo, J., Backes, U., Barreiros, T., Bertani, I., Bjourson, A. J., Bruckner, M., Bruschi, C. V., Carignani, G., Castagnoli, L., Cerdan, E., Clemente, M. L., Coblenz, A., Coglievina, M., Coissac, E., Defoor, E., Del Bino, S., Delius, H., Delneri, D., de Wergifosse, P., Dujon, B., Kleine, K., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII." Nature 387:81-84.9169869
- Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106
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