Purine-cytosine permease FCY21 (P40039)

Identification
NamePurine-cytosine permease FCY21
Synonyms
  • PCP FCY21
  • Cytosine/purine transport protein FCY21
  • Fluorocytosine resistance protein 21
Gene NameFCY21
Enzyme ClassNot Available
Biological Properties
General FunctionInvolved in nucleobase transmembrane transporter activity
Specific FunctionProbable purine-cytosine permease
Cellular LocationMembrane; Multi-pass membrane protein
SMPDB PathwaysNot Available
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
YMDB00651CytosineShow
YMDB00698GuanineShow
YMDB00862hydronShow
YMDB00887AdenineShow
GO Classification
Component
cell part
membrane
Function
nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity
nucleobase transmembrane transporter activity
transporter activity
transmembrane transporter activity
substrate-specific transmembrane transporter activity
Process
nucleobase, nucleoside, nucleotide and nucleic acid transport
transmembrane transport
establishment of localization
transport
Gene Properties
Chromosome Locationchromosome 5
LocusYER060W
Gene Sequence>1587 bp ATGCCTCAAACGCACGAAATGTCCCTGAACGGCACTCAATACTTAAAATATGAACTTAAA GACCTTGAGTCTCGAGCTCACGATGCAAAGACTCCTTCAACAAATGAATTCTATGATGAT GTAGAATCGCACGGAACAGAAGAATTAGTTGAAGCTAAACTGTCGTTTTTGAACAGAATT GCTGCTGGTTTAAGTGCCGAGACAAAGGGTATTGAACCGATTACAGAAGATGAAAAAACT GATGATTCTATACTGAACGCTGCATCTATGTGGTTTTCAGCAAATATGGTTCTGCCTGCT TATGCCATTGGCGCCCTAGGGCCTATGGTGTTTGATCTAAATTTCGGCCAAAGCGTTTTC GTTATTATTTTCTTTAACCTCTTAGGCTTGGTATCAGTTGCTTTCTTTTCTGTTTTCGGT GCAGAGCTGGGCCTAAGACAGATGATTTTGTCTAGATATTTAGTTGGCAATATCGCAGCC AGGATCTTCTCTTTCATCAATTTTATTGCCTGTATCGGTTGGGGTATCGTTAATACCGTA GCAAGCTCGCAAGTCCTGAATATGGTTAACCCCGGTCATCAATGTCCTCTCTGGGCTGGT TGTATAGTTATTATCGGTGCTACTGTAATTGTAACTTTTTTCGGCTATGGAGTCATTCAT GCTTACGAGAAATGGGCGTGGGTACCAAATTTTGCCGTTTTTTTGGTAATAATTGCTCGT TTGGCAAGGTCTAAAAAATTTGTCCTTGGGGAGTGGACATCTGGTCCTACTACAGCAGGT AACGTGCTTTCATTTGGATCAACAGTTTATGGGTTTGCTGCAGGCTGGACAACATATGCG GCTGACTATACCGTTTATATGCCAAGGAAAACGAACAAGTATAAAATTTTTTTCTCGCTT GTAGTTGGGTTAGCAACACCATTATATTTTACTATGATACTTGGTGCAGCTGTAGCAATG GCAGCTATCGGCGATCCAGCCTGGAAGACGTATTATGACGAAAATTCCATAGGTGGTTTA ACTTTTGCCGTTCTTGTCCCTAATTCTGTTCACGGATTCGGTCAGTTCTGTTGCGTGTTA TTGTCTCTGTCCACTATCGCTAATAATGTTCCCAACATGTATACTATTGCTTTATCGGTG CAAGCCACGTGGGAACCTCTTGCGAAAGTCCCAAGAGTTATTTGGACTTTATTAGGCAAT GCGGCCGCACTGGGTATTGCCATTCCTGCCTGCTACTATTTTTCTACCTTCATGAATTAC TTCATGGATTCCATAGGTTATTATTTGGCTATTTATATTGCCATTGCATGTTCAGAGCAT TTTATTTATAGGCGTTCCTTCAGTGCTTACAATGTTGATGATTGGGATAGTTGGGAACGT CTACCTATCGGCATTGCAGGTACTGCTGCCTTAATTGTTGGTGCCTTTGGCGTAGCGTTG GGTATGTGCCAAACTTATTGGGTTGGCGAGATCAGCCGTTTGATCGGAGACTACGGTGGT GATATTGGATTCGAGTTAGGACTAAGTTGGGCATTTATAGTTTACAACATTGCTAGACCC TTTGAGCTCAAGTACTTTGGTCGTTAA
Protein Properties
Pfam Domain Function
Protein Residues528
Protein Molecular Weight58049.60156
Protein Theoretical pI5.22
Signalling Regions
  • None
Transmembrane Regions
  • 91-111
  • 119-139
  • 162-182
  • 199-219
  • 222-242
  • 261-281
  • 296-316
  • 341-361
  • 394-414
  • 417-437
  • 461-481
  • 494-514
Protein Sequence>Purine-cytosine permease FCY21 MPQTHEMSLNGTQYLKYELKDLESRAHDAKTPSTNEFYDDVESHGTEELVEAKLSFLNRI AAGLSAETKGIEPITEDEKTDDSILNAASMWFSANMVLPAYAIGALGPMVFDLNFGQSVF VIIFFNLLGLVSVAFFSVFGAELGLRQMILSRYLVGNIAARIFSFINFIACIGWGIVNTV ASSQVLNMVNPGHQCPLWAGCIVIIGATVIVTFFGYGVIHAYEKWAWVPNFAVFLVIIAR LARSKKFVLGEWTSGPTTAGNVLSFGSTVYGFAAGWTTYAADYTVYMPRKTNKYKIFFSL VVGLATPLYFTMILGAAVAMAAIGDPAWKTYYDENSIGGLTFAVLVPNSVHGFGQFCCVL LSLSTIANNVPNMYTIALSVQATWEPLAKVPRVIWTLLGNAAALGIAIPACYYFSTFMNY FMDSIGYYLAIYIAIACSEHFIYRRSFSAYNVDDWDSWERLPIGIAGTAALIVGAFGVAL GMCQTYWVGEISRLIGDYGGDIGFELGLSWAFIVYNIARPFELKYFGR
References
External Links
ResourceLink
Saccharomyces Genome Database FCY21
Uniprot IDP40039
Uniprot NameFCY21_YEAST
GenBank Gene IDU18813
Genebank Protein ID1381128
General Reference
  • Dietrich, F. S., Mulligan, J., Hennessy, K., Yelton, M. A., Allen, E., Araujo, R., Aviles, E., Berno, A., Brennan, T., Carpenter, J., Chen, E., Cherry, J. M., Chung, E., Duncan, M., Guzman, E., Hartzell, G., Hunicke-Smith, S., Hyman, R. W., Kayser, A., Komp, C., Lashkari, D., Lew, H., Lin, D., Mosedale, D., Davis, R. W., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome V." Nature 387:78-81.9169868
  • Kim, H., Melen, K., Osterberg, M., von Heijne, G. (2006). "A global topology map of the Saccharomyces cerevisiae membrane proteome." Proc Natl Acad Sci U S A 103:11142-11147.16847258