Identification
NamePhosphate permease PHO89
Synonyms
  • Na(+)/Pi cotransporter PHO89
Gene NamePHO89
Enzyme ClassNot Available
Biological Properties
General FunctionInvolved in inorganic phosphate transmembrane transporter activity
Specific FunctionSodium-phosphate symporter. Active in early growth phase
Cellular LocationMembrane; Multi-pass membrane protein
SMPDB PathwaysNot Available
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
YMDB00862hydronShow
GO Classification
Component
cell part
membrane
Function
inorganic phosphate transmembrane transporter activity
transporter activity
transmembrane transporter activity
substrate-specific transmembrane transporter activity
ion transmembrane transporter activity
anion transmembrane transporter activity
inorganic anion transmembrane transporter activity
phosphate transmembrane transporter activity
Process
phosphate transport
establishment of localization
transport
ion transport
anion transport
inorganic anion transport
Gene Properties
Chromosome Locationchromosome 2
LocusYBR296C
Gene Sequence>1725 bp ATGGCTTTACATCAATTTGACTATATTTTTGCCATTGCCATGTTATTTGCATTTTTGGAT GCCTTTAACATCGGGGCAAACGACGTGGCGAACTCATTCGCGTCGTCGATCTCTTCTAGA TCTCTAAAATACTGGCAAGCCATGGTTTTGGCGGGTCTCTGTGAGTTCTTGGGTGCTGTC TTGGCAGGCGCAAGAGTTTCTGGTACTATCAAGAACAACATTATAGATTCCTCCATTTTT ACCAACGACCCCGCTGTTTTAATGCTTACTATGACCAGTGCTTTGATTGGCTCGTCTTGT TGGTTAACATTTGCTACTGCAATCGGAATGCCAGTTTCTACTACACATTCCATTGTTGGT GGTACAATTGGCGCTGGGATTGCAGCCGGTGGAGCTAACGGTGTCGTTTGGGGTTGGAGT GGTGTTTCTCAAATTATTGCGTCATGGTTCATTGCTCCGATTTTGGCAGGCGCGATCGCA GCTATAGTTTTTTCAATTTCTAGGTTTTCTGTCCTTGAAGTTAAGTCTTTGGAAAGATCG ATTAAGAATGCTTTACTGCTGGTTGGTGTTTTAGTATTCGCCACTTTCTCTATCTTAACA ATGTTGATTGTCTGGAAGGGTTCTCCAAACCTACACTTGGACGATTTATCTGAAACTGAA ACTGCCGTATCTATTGTTCTCACAGGTGCAATTGCTTCGATCGTTTACTTCATCTTTTTC TACCCATTCTACAGAAGAAAAGTTTTGGACCAAGATTGGACACTAAAGTTGATTGATATT TTCAGAGGTCCATCTTTTTACTTTAAGTCCACTGATGATATCCCACCAATGCCAGAAGGC CATCAATTAACAATCGATTATTACGAGGGCAGAAGAAATCTTGGAACAACTGTTTCTGTT GAAGACGAAGAAAATAAGGCAGCGAGTAATTCTAATGATTCCGTCAAAAACAAAGAAGAC ATCCAGGAAGTGGACCTGGTTAGAACTGAAACTGAACCAGAAACAAAGTTGTCAACGAAA CAATATTGGTGGTCATTATTAAAGCAAGGACCTAAAAAATGGCCCTTATTGTTCTGGTTA GTAATCTCTCATGGTTGGACTCAAGACGTCATTCATGCTCAAGTTAATGATAGAGATATG TTATCTGGTGACCTGAAAGGAATGTACGAAAGATCTAAATTTTACGACAATAGAGTAGAA TATATCTATTCGGTTCTCCAAGCCATTACTGCAGCCACTATGTCTTTTGCTCATGGAGCT AATGACGTTGCCAACGCTACTGGTCCTTTGTCTGCTGTGTATGTGATCTGGAAAACTAAC ACTATTGGGGCAAAGTCCGAAGTTCCCGTGTGGGTTCTGGCTTATGGTGGTGTTGCCTTA GTTATTGGTTGCTGGACTTATGGTTACAATATTATCAAAAATCTAGGTAATAAGATGATT TTGCAGTCGCCATCAAGAGGCTTTTCAATTGAACTAGCTGTTGCTATTACTACTGTCATG GCTACCCAATTAGGTATTCCTACCTCAACAACCCAGATCGCCGTTGGTGGTATTGTCGCT GTTGGTTTATGTAACAAGGATCTCAAATCAGTTAATTGGAGAATGGTAGCCTGGTGTTAT TCTGGTTGGTTTTTAACTTTACCAATTGCTGGTTTGATTGCCGGTATCATAAATGGTATC ATTTTGAATGCTCCTCGCTTTGGTGTGGAATACCAAATGACATAA
Protein Properties
Pfam Domain Function
Protein Residues574
Protein Molecular Weight62652.89844
Protein Theoretical pI6.41
Signalling Regions
  • None
Transmembrane Regions
  • 6-26
  • 44-64
  • 85-105
  • 118-138
  • 146-166
  • 185-205
  • 223-243
  • 355-375
  • 399-419
  • 448-468
  • 504-524
  • 542-562
Protein Sequence>Phosphate permease PHO89 MALHQFDYIFAIAMLFAFLDAFNIGANDVANSFASSISSRSLKYWQAMVLAGLCEFLGAV LAGARVSGTIKNNIIDSSIFTNDPAVLMLTMTSALIGSSCWLTFATAIGMPVSTTHSIVG GTIGAGIAAGGANGVVWGWSGVSQIIASWFIAPILAGAIAAIVFSISRFSVLEVKSLERS IKNALLLVGVLVFATFSILTMLIVWKGSPNLHLDDLSETETAVSIVLTGAIASIVYFIFF YPFYRRKVLDQDWTLKLIDIFRGPSFYFKSTDDIPPMPEGHQLTIDYYEGRRNLGTTVSV EDEENKAASNSNDSVKNKEDIQEVDLVRTETEPETKLSTKQYWWSLLKQGPKKWPLLFWL VISHGWTQDVIHAQVNDRDMLSGDLKGMYERSKFYDNRVEYIYSVLQAITAATMSFAHGA NDVANATGPLSAVYVIWKTNTIGAKSEVPVWVLAYGGVALVIGCWTYGYNIIKNLGNKMI LQSPSRGFSIELAVAITTVMATQLGIPTSTTQIAVGGIVAVGLCNKDLKSVNWRMVAWCY SGWFLTLPIAGLIAGIINGIILNAPRFGVEYQMT
References
External Links
ResourceLink
Saccharomyces Genome Database PHO89
Uniprot IDP38361
Uniprot NamePHO89_YEAST
GenBank Gene IDZ36165
Genebank Protein ID536756
General Reference
  • Feldmann, H., Aigle, M., Aljinovic, G., Andre, B., Baclet, M. C., Barthe, C., Baur, A., Becam, A. M., Biteau, N., Boles, E., Brandt, T., Brendel, M., Bruckner, M., Bussereau, F., Christiansen, C., Contreras, R., Crouzet, M., Cziepluch, C., Demolis, N., Delaveau, T., Doignon, F., Domdey, H., Dusterhus, S., Dubois, E., Dujon, B., El Bakkoury, M., Entian, K. D., Feurmann, M., Fiers, W., Fobo, G. M., Fritz, C., Gassenhuber, H., Glandsdorff, N., Goffeau, A., Grivell, L. A., de Haan, M., Hein, C., Herbert, C. J., Hollenberg, C. P., Holmstrom, K., Jacq, C., Jacquet, M., Jauniaux, J. C., Jonniaux, J. L., Kallesoe, T., Kiesau, P., Kirchrath, L., Kotter, P., Korol, S., Liebl, S., Logghe, M., Lohan, A. J., Louis, E. J., Li, Z. Y., Maat, M. J., Mallet, L., Mannhaupt, G., Messenguy, F., Miosga, T., Molemans, F., Muller, S., Nasr, F., Obermaier, B., Perea, J., Pierard, A., Piravandi, E., Pohl, F. M., Pohl, T. M., Potier, S., Proft, M., Purnelle, B., Ramezani Rad, M., Rieger, M., Rose, M., Schaaff-Gerstenschlager, I., Scherens, B., Schwarzlose, C., Skala, J., Slonimski, P. P., Smits, P. H., Souciet, J. L., Steensma, H. Y., Stucka, R., Urrestarazu, A., van der Aart, Q. J., van Dyck, L., Vassarotti, A., Vetter, I., Vierendeels, F., Vissers, S., Wagner, G., de Wergifosse, P., Wolfe, K. H., Zagulski, M., Zimmermann, F. K., Mewes, H. W., Kleine, K. (1994). "Complete DNA sequence of yeast chromosome II." EMBO J 13:5795-5809.7813418
  • Martinez, P., Persson, B. L. (1998). "Identification, cloning and characterization of a derepressible Na+-coupled phosphate transporter in Saccharomyces cerevisiae." Mol Gen Genet 258:628-638.9671031