| Identification |
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| Name | Glycogenin-1 |
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| Synonyms | - Glycogen synthesis initiator protein 1
- Glycogenin glucosyltransferase 1
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| Gene Name | GLG1 |
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| Enzyme Class | |
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| Biological Properties |
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| General Function | Involved in transferase activity, transferring glycosyl groups |
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| Specific Function | Self-glucosylating initiator of glycogen synthesis. Catalyzes the formation of a short alpha (1,4)-glucosyl chain covalently attached via a glucose 1-O-tyrosyl linkage to internal tyrosine residues. These chains act as primers for the elongation reaction catalyzed by glycogen synthase. Capable of transferring glucosyl residues to unbound acceptors such as free oligoglucans or oligoglucan derivatives |
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| Cellular Location | Not Available |
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| SMPDB Pathways | Not Available |
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| KEGG Pathways | Not Available |
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| SMPDB Reactions | Not Available |
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| KEGG Reactions | Not Available |
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| Metabolites | | YMDB ID | Name | View |
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| YMDB00212 | Uridine diphosphate glucose | Show | | YMDB00307 | Uridine 5'-diphosphate | Show |
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| GO Classification | | Component |
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| Not Available | | Function |
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| catalytic activity | | transferase activity | | transferase activity, transferring glycosyl groups | | Process |
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| Not Available |
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| Gene Properties |
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| Chromosome Location | chromosome 11 |
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| Locus | YKR058W |
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| Gene Sequence | >1857 bp
ATGGGAATGTATAAGAAGCTGGCTATTGCCACATTGCTCTATTCCGCAGATTATTTACCA
GGTGTGTTTGCCCTTGGTCACCAAGTGAATAAATTGTTAGAGGAAGCAGGCAAAAAAGGC
GACATTGAAACATGCCTTATTGTGACGACCTCTCTATTTAATGGCACTTTAAGCGAGCTA
GCCAAGAATATTTTACAATCAATATACACCAAAATTGTGTTGGTAGAGCCTTTAAATTGC
CAAGAAGAAAGCATACAGAAGAATAGTGAGAATTTAGCTCTTTTGGAAAGACCTGAATTA
TCCTTTGCCTTAATCAAAGCAAGACTATGGGAATTAACTCAGTTCGAACAAGTTCTTTAC
TTGGATTCCGACACTTTACCTCTGAATAAAGAATTTTTAAAGTTGTTTGACATTATGTCT
AAACAAACCACGTCACAAGTGGGTGCTATTGCTGATATCGGCTGGCCTGATATGTTCAAT
AGCGGTGTCATGATGCTAATACCGGATGCTGATACTGCATCCGTTTTACAAAATTATATT
TTTGAAAACACTTCAATTGATGGTTCTGACCAGGGCATTTTAAACCAGTTCTTCAATCAA
AATTGTTGCACTGATGAGCTAGTTAAAGACAGTTTCTCTCGAGAATGGGTACAGTTATCA
TTTACGTATAACGTAACTATTCCTAATTTAGGCTACCAATCTTCACCTGCTATGAATTAC
TTTAAACCTAGCATTAAGTTGATTCATTTCATTGGGAAACACAAGCCATGGTCATTGTGG
TCCCAAAAGAATTTCATTAAAAACGAGTATCATGATCAATGGAATGAGGTATACGAGGAA
TTTAAGGAAGAACATCAATTAAATAACGAAGTTTCGAAGCCAAAGATTAGTGATTCCGAT
AAAACTGAGACTCCTGAAACGATAACCCCAGTGGATGCCCCTCCATCGAACGAACCCACT
ACGAATCAAGAGATCGACACAATTAGTACAGTGGAAGAAAACGTGGACAACCAGAACGCC
GAGCCTGTTCCTAACTCGGATCATAGCCCTGCTCCTAACCCTGTCCCATTGGATTTTACC
AAGTGGTTAACAACCTTTATTAACAAAGATCACTTGACTAATCAGCCAGTAAATGAAAGC
AGAGAATATTCGAAAGAGAATGATAACAATATAATCAATAGCAGTTCAAACCGCGACCAA
GAAAGTCCTCCAAATAGTACTCAGGAACTAAACAGCTCTTATAGCGTTGTGAGTACTCAA
GCTGATAGCGATGAGCACCAAAATGCAGAAGAGGAGGATAGTACGACAGATAACGCTTCA
AATTCTGGAGAAGAAAGCCACCTCGATGATATAAGCACGGCCGCTTCTTCCAATAACAAT
GTAAGTAATCAACCAGATGGCAAAAATTTTAGCAATTCTAAAGAAAATAATATCAGTGTC
GAATCTAGCCCTTCAAATCCAGAACAGAAAAGGTCAACTGACAATATACAAAAACCAAGT
GTTTCTACTAATGACTTACCAGACGACGTAGAACCACATACCTCTGTTGATGACAATATA
CAGTACTTAGAAAAAGACAAGGAAGGTTATGAAGAATTTCTTCCGGACGTGTACGAGTCA
AATGCAATCGATAACGAAGAAGAATTTTTTGATGACGATGCAAGAGATGCTACCGAAGGA
GAAACGAAGACGAGTGCAGTTGCAGATAAACAGGAGGATATGAAACTTACAGCAGAGGAA
ACCAACCAACCGCAACAAGAAATGCCCAACTTCAAATTTGACTGGGAGGACTCTGATTAT
CTATCCAAAGTAGAGAGGTGTTTCCCTGATGATATTTTTGAGTATGCAGTAGAGTAA |
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| Protein Properties |
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| Pfam Domain Function | |
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| Protein Residues | 616 |
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| Protein Molecular Weight | 69723.39844 |
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| Protein Theoretical pI | 3.98 |
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| Signalling Regions | |
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| Transmembrane Regions | |
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| Protein Sequence | >Glycogenin-1
MYKKLAIATLLYSADYLPGVFALGHQVNKLLEEAGKKGDIETCLIVTTSLFNGTLSELAK
NILQSIYTKIVLVEPLNCQEESIQKNSENLALLERPELSFALIKARLWELTQFEQVLYLD
SDTLPLNKEFLKLFDIMSKQTTSQVGAIADIGWPDMFNSGVMMLIPDADTASVLQNYIFE
NTSIDGSDQGILNQFFNQNCCTDELVKDSFSREWVQLSFTYNVTIPNLGYQSSPAMNYFK
PSIKLIHFIGKHKPWSLWSQKNFIKNEYHDQWNEVYEEFKEEHQLNNEVSKPKISDSDKT
ETPETITPVDAPPSNEPTTNQEIDTISTVEENVDNQNAEPVPNSDHSPAPNPVPLDFTKW
LTTFINKDHLTNQPVNESREYSKENDNNIINSSSNRDQESPPNSTQELNSSYSVVSTQAD
SDEHQNAEEEDSTTDNASNSGEESHLDDISTAASSNNNVSNQPDGKNFSNSKENNISVES
SPSNPEQKRSTDNIQKPSVSTNDLPDDVEPHTSVDDNIQYLEKDKEGYEEFLPDVYESNA
IDNEEEFFDDDARDATEGETKTSAVADKQEDMKLTAEETNQPQQEMPNFKFDWEDSDYLS
KVERCFPDDIFEYAVE |
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| References |
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| External Links | |
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| General Reference | - Cheng, C., Mu, J., Farkas, I., Huang, D., Goebl, M. G., Roach, P. J. (1995). "Requirement of the self-glucosylating initiator proteins Glg1p and Glg2p for glycogen accumulation in Saccharomyces cerevisiae." Mol Cell Biol 15:6632-6640.8524228
- Dujon, B., Alexandraki, D., Andre, B., Ansorge, W., Baladron, V., Ballesta, J. P., Banrevi, A., Bolle, P. A., Bolotin-Fukuhara, M., Bossier, P., et, a. l. .. (1994). "Complete DNA sequence of yeast chromosome XI." Nature 369:371-378.8196765
- Mu, J., Cheng, C., Roach, P. J. (1996). "Initiation of glycogen synthesis in yeast. Requirement of multiple tyrosine residues for function of the self-glucosylating Glg proteins in vivo." J Biol Chem 271:26554-26560.8900126
- Parrou, J. L., Enjalbert, B., Plourde, L., Bauche, A., Gonzalez, B., Francois, J. (1999). "Dynamic responses of reserve carbohydrate metabolism under carbon and nitrogen limitations in Saccharomyces cerevisiae." Yeast 15:191-203.10077186
- Brachat, S., Dietrich, F. S., Voegeli, S., Zhang, Z., Stuart, L., Lerch, A., Gates, K., Gaffney, T., Philippsen, P. (2003). "Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii." Genome Biol 4:R45.12844361
- Cliften, P., Sudarsanam, P., Desikan, A., Fulton, L., Fulton, B., Majors, J., Waterston, R., Cohen, B. A., Johnston, M. (2003). "Finding functional features in Saccharomyces genomes by phylogenetic footprinting." Science 301:71-76.12775844
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