1,4-alpha-glucan-branching enzyme (P32775)

Identification
Name1,4-alpha-glucan-branching enzyme
Synonyms
  • Glycogen-branching enzyme
Gene NameGLC3
Enzyme Class
Biological Properties
General FunctionInvolved in catalytic activity
Specific FunctionTransfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain
Cellular LocationCytoplasmic
SMPDB Pathways
Starch and sucrose metabolismPW002481 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG Pathways
Starch and sucrose metabolismec00500 Map00500
SMPDB Reactions
Amylose → Glycogen
KEGG Reactions
amylose → Glycogen + water
Metabolites
YMDB IDNameView
YMDB00881GlycogenShow
YMDB00890waterShow
YMDB16158AmyloseShow
GO Classification
Component
Not Available
Function
catalytic activity
binding
ion binding
cation binding
hydrolase activity
hydrolase activity, acting on glycosyl bonds
hydrolase activity, hydrolyzing O-glycosyl compounds
Process
metabolic process
primary metabolic process
carbohydrate metabolic process
Gene Properties
Chromosome Locationchromosome 5
LocusYEL011W
Gene Sequence>2115 bp ATGTACAACATTCCAGATAATGTCAAAGGGGCTGTAGAATTTGATCCATGGTTGAAACCG TTTGCCGATGTACTTTCTGAAAGAAGATACCTAGCTGACAAGTGGTTGTACGACATAACT CATGCTACGCCTGATGGTTCGTATCAGTCACTCAGTAAGTTTGCTAGAGATTCATACAAG TCATATGGGTTGCATGCCAATCCGGAAACCAAAGAAATCACTTACAAAGAGTGGGCACCC AATGCGGAACGTGCATTTCTAGTGGGAGATTTCAATAACTGGGATACCACATCTCATGAG CTCAAGAACAAGGACGAATTTGGAAATTTTACAATCACACTTCATCCTTTACCTAACGGC GATTTCGCCATCCCTCATGATTCGAAGATTAAAGTCATGTTTATTTTGCCAGATGGTTCC AAGATCTTTCGTTTACCTGCGTGGATCACAAGGGCTACACAGCCTTCTAAGGAAACTTCT AAACAGTTCGGGCCCGCATATGAAGGTAGGTTTTGGAATCCAGAGAACCCCTACAAATTT GTACATCCAAGGCCAAAGTTTAGTGAATCTGTAGATTCCTTAAGGATTTATGAAGCCCAC GTCGGTATTTCGAGTCCAGAACCAAAGATAACCACATATAAAGAATTTACTGAGAAGGTC TTACCCAGAATCAAATATCTTGGCTACGATGCAATTCAATTAATGGCTATTATGGAACAT GCTTATTATGCATCATTTGGCTACCAAGTGACCAATTTTTTTGCGGCGAGCTCCCGTTTC GGCACCCCTGAGGAATTAAAGGAGCTGATTGATACTGCACATTCTATGGGCATCCTAGTT TTATTGGATGTAGTTCATAGCCATGCTTCTAAAAACGTCGAGGATGGGTTGAACATGTTT GACGGTTCTGATCATCAGTATTTCCATTCTATAAGCTCCGGTAGGGGTGAGCATCCGCTG TGGGATTCCCGTCTTTTTAATTACGGAAAATTTGAAGTGCAGCGATTCTTATTAGCAAAC CTGGCATTTTATGTTGACGTTTATCAGTTTGATGGGTTTAGATTCGATGGTGTCACATCA ATGTTATACGTTCATCATGGTGTTGGTGCCGGTGGGTCTTTTAGCGGTGACTATAACGAA TATCTTTCTCGTGACAGGTCCTTCGTCGATCATGAAGCCTTAGCTTATTTAATGTTAGCC AATGATTTGGTTCACGAAATGTTGCCAAATCTGGCTGTAACTGTTGCAGAAGATGTCTCT GGTTATCCAACTTTATGTTTACCCCGCTCCATAGGTGGTACTGGTTTCGACTACAGATTA GCAATGGCTTTGCCTGATATGTGGATCAAACTAATCAAGGAGAAGAAAGATGATGAATGG GAGATGGGAAGTATTGTATACACTTTAACTAATAGACGATATGGTGAAAAAGTGGTTGCT TATTGTGAGTCGCACGACCAAGCTTTAGTTGGTGATAAGACATTAGCGTTTTGGTTGATG GATGCCGCTATGTACACCGATATGACTGTATTGAAGGAACCATCCATCGTTATTGACCGT GGTATTGCTCTACACAAGATGATTAGGCTGATCACTCACTCGCTGGGAGGCGAGGCTTAT TTGAACTTCGAAGGTAATGAGTTCGGTCATCCAGAATGGTTGGATTTCCCTAATGTTAAC AATGGCGATACGTACAAGTATGCTCGTAGGCAGTTTAATTTGGCTGATGATCCCTTACTG CGTTACCAGAATTTAAATGAGTTTGATAGATCAATGCAATTATGTGAGAAAAGGCATAAG TGGCTGAACACGAAACAGGCTTATGTTTCATTAAAACATGAAGGTGACAAAATGATTGTG TTTGAAAGAAATAATCTGTTGTTTATTTTCAACTTCCATCCTACAAACAGCTACAGCGAT TATAGAGTTGGTGTCGAAAAAGCTGGTACTTATCACATCGTGTTGAACTCAGATCGTGCT GAATTTGGTGGACATAACAGAATCAACGAAAGTTCCGAATTCTTTACCACCGATTTGGAA TGGAACAACAGGAAGAACTTCCTCCAAGTTTATATTCCTAGTAGAGTCGCTTTGGTGCTT GCCTTAAAAGAATGA
Protein Properties
Pfam Domain Function
Protein Residues704
Protein Molecular Weight81114.89844
Protein Theoretical pI6.1
Signalling Regions
  • None
Transmembrane Regions
  • None
Protein Sequence>1,4-alpha-glucan-branching enzyme MYNIPDNVKGAVEFDPWLKPFADVLSERRYLADKWLYDITHATPDGSYQSLSKFARDSYK SYGLHANPETKEITYKEWAPNAERAFLVGDFNNWDTTSHELKNKDEFGNFTITLHPLPNG DFAIPHDSKIKVMFILPDGSKIFRLPAWITRATQPSKETSKQFGPAYEGRFWNPENPYKF VHPRPKFSESVDSLRIYEAHVGISSPEPKITTYKEFTEKVLPRIKYLGYDAIQLMAIMEH AYYASFGYQVTNFFAASSRFGTPEELKELIDTAHSMGILVLLDVVHSHASKNVEDGLNMF DGSDHQYFHSISSGRGEHPLWDSRLFNYGKFEVQRFLLANLAFYVDVYQFDGFRFDGVTS MLYVHHGVGAGGSFSGDYNEYLSRDRSFVDHEALAYLMLANDLVHEMLPNLAVTVAEDVS GYPTLCLPRSIGGTGFDYRLAMALPDMWIKLIKEKKDDEWEMGSIVYTLTNRRYGEKVVA YCESHDQALVGDKTLAFWLMDAAMYTDMTVLKEPSIVIDRGIALHKMIRLITHSLGGEAY LNFEGNEFGHPEWLDFPNVNNGDSYKYARRQFNLADDPLLRYQNLNEFDRSMQLCEKRHK WLNTKQAYVSLKHEGDKMIVFERNNLLFIFNFHPTNSYSDYRVGVEKAGTYHIVLNSDRA EFGGHNRINESSEFFTTDLEWNNRKNFLQVYIPSRVALVLALKE
References
External Links
ResourceLink
Saccharomyces Genome Database GLC3
Uniprot IDP32775
Uniprot NameGLGB_YEAST
GenBank Gene IDM76739
Genebank Protein ID171569
General Reference
  • Thon, V. J., Vigneron-Lesens, C., Marianne-Pepin, T., Montreuil, J., Decq, A., Rachez, C., Ball, S. G., Cannon, J. F. (1992). "Coordinate regulation of glycogen metabolism in the yeast Saccharomyces cerevisiae. Induction of glycogen branching enzyme." J Biol Chem 267:15224-15228.1634552
  • Dietrich, F. S., Mulligan, J., Hennessy, K., Yelton, M. A., Allen, E., Araujo, R., Aviles, E., Berno, A., Brennan, T., Carpenter, J., Chen, E., Cherry, J. M., Chung, E., Duncan, M., Guzman, E., Hartzell, G., Hunicke-Smith, S., Hyman, R. W., Kayser, A., Komp, C., Lashkari, D., Lew, H., Lin, D., Mosedale, D., Davis, R. W., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome V." Nature 387:78-81.9169868
  • Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106
  • Albuquerque, C. P., Smolka, M. B., Payne, S. H., Bafna, V., Eng, J., Zhou, H. (2008). "A multidimensional chromatography technology for in-depth phosphoproteome analysis." Mol Cell Proteomics 7:1389-1396.18407956