Identification
NameSignaling mucin MSB2
Synonyms
  • Multicopy suppressor of bud emergence 2
  • Osmosensor MSB2
Gene NameMSB2
Enzyme ClassNot Available
Biological Properties
General Functionsignal transduction involved in filamentous growth
Specific FunctionPlasma membrane signaling mucin that promotes activation of the MAPK for the filamentous growth pathway. Partially redundant with the SHO1 osmosensing branch for the activation of STE11.
Cellular LocationNot Available
SMPDB Pathways
Stress-activated signalling pathways: high osmolarity 1469654356PW002970 ThumbThumb?image type=greyscaleThumb?image type=simple
Stress-activated signalling pathways: high osmolarity test 1PW002773 ThumbThumb?image type=greyscaleThumb?image type=simple
Stress-activated signalling pathways: starvation test 1PW003483 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
osmosensory signaling pathway via Sho1 osmosensor
site of polarized growth
osmosensor activity
response to osmotic stress
integral component of plasma membrane
signal transduction involved in filamentous growth
hyperosmotic response
extracellular region
cellular bud site selection
establishment of cell polarity
fungal-type cell wall organization
cell surface
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>3921 bp ATGCAGTTTCCATTCGCTTGTCTCCTATCGACCCTTGTAATTAGTGGGTCATTGGCCCGG GCCAGCCCCTTCGACTTTATATTCGGCAATGGAACGCAACAAGCTCAGAGCCAAAGCGAG AGTCAAGGTCAAGTTTCTTTCACCAATGAAGCTTCTCAGGATAGTTCCACCACCTCTTTG GTAACAGCCTATTCTCAAGGTGTTCATTCGCACCAGTCTGCAACAATAGTGAGTGCCACA ATCTCTTCCCTCCCATCTACTTGGTATGATGCGAGCTCCACTTCCCAGACTTCTGTGTCA TATGCCAGTCAAGAATCCGACTATGCCGTTAATCAAAACTCTTGGAGCGCGTCTACTAAT CAACTGCCATCTACCAGTACGACAAGCTACTATGCGCCAACCTTCAGTACATCGGCCGAT TTTGCTGCTTCTAGTGTAAATGCAGCTTCTGATGTCTCCACTGCCAGTGTTCCCATTGAT ACGAGTGCTAATTCTATCCCTTTCACAACTACAAGTAACATAGAGACTACAACGAGTGCA CCTCTCACTTCGGACACTCCACTTATTTCCACTAGTACGATGTCCGCAGCTGATAACGTA TTTTCGTCAGCAAACCCTATTTCTGCCTCCCTAACAACCACCGATAGTTCAGAAAGTTTT GACCAAACTTCGACTGCTGGTGCCATTCCGGTGCAAAGTTCAGCAGATTTTAGTAGTTCT AGTGAAATTTTAGTACAAAGTTCGGCGGATTTCAGTAGCCCTAGTTCTCCAACTACTACC GATATATCGCTATCAGCTGCCCCACTGCAAACAAGTGAATCAAGCAGTTTTACCACTGCA TCAGCAGCTCTACCAGTAAGTTCAACAGACGTTGATGGCTCAAGCGCCTCACCTGTAGTG AGCATGAGCGCCGCAGGACAAATAGCTAGCTCAAGCAGCACAGATAATCCAACTATGTCA GAAACCTTTTCGTTAACATCTACAGAAGTTGATGGTTCCGATGTTTCATCAACAGTGAGC GCATTATTATCGGCTCCTTTTTTACAAACAAGTACTTCCAACAGTTTCAGCATTGTTAGC CCATCGGTATCTTTTGTTCCATCACAGAGTTCCTCAGACGTTGCTAGCTCCAGTACTGCA AATGTAGTTAGTTCATCCTTTTCTGATATTCCACCGCAAACTAGTACCTCAGGGAGCGTA GTTTCGGTAGCGCAATCCGCATCTGCCCTCGCATTTCAAAGTTCAACAGAGGTATATGGT GCCAGTGCCTCGAGCACAATGAGTTCATTATTATCAACTACTTCGCTACAGTCTACTACT TTGGATAGCTCAAGTTTAGCTAGCTCCTCTGCGTCGAGTTCAGACCTTACAGATTATGGC GTCTCCAGTACAGCAAGCATACCGCTGTTGTCAGCCTCAGAACAAGCAAGTACTTCCAGC AGTTTTAGCGTTGTTAGCCCTTCGGTATCTTTTGTTCCATCACAAAGTTCCTCAGATGTT GCTAGCACCAGTGCTCCAAGTGTAGTTAGTTCATCCTTTTCTTATACTTCACTGCAAGCA GGTGGCTCTAGCATGACCAATCCCTCTTCATCAACTATAGTATATTCAAGTAGTACTGGC AGTTCTGAGGAATCCGCTGCATCTACAGCTTCTGCAACACTGTCGGGCTCCTCGTCTACT TATATGGCAGGAAATTTGCAATCACAGCCTCCATCCACTTCAAGTTTGCTTTCGGAGTCT CAAGCTACAAGCACTTCAGCTGTGCTAGCTAGCAGTTCTGTTTCTACAACTTCACCCTAT ACCACTGCAGGTGGTGCATCTACAGAGGCCTCATCCCTCATATCATCTACATCTGCGGAA ACTTCCCAGGTAAGTTATTCACAAAGCACAACTGCATTGCAAACTTCCTCATTCGCATCG TCTTCAACAACAGAAGGAAGTGAAACATCTAGTCAAGGTTTTTCTACCAGCTCTGTTTTA GTTCAAATGCCTTCTTCGATTTCCAGCGAATTCTCACCCTCTCAGACGACAACTCAAATG AATTCTGCAAGCTCATCATCTCAGTACACTATATCATCCACTGGTATACTTTCTCAGGTT TCAGACACATCGGTGTCTTATACAACTTCAAGTTCGTCTGTTTCTCAAGTTTCAGACACA CCAGTTTCTTATACAACTTCAAGTTCGTCTGTTTCTCAAGTTTCAGACACACCGGTTTCT TATACAACTTCAAGTTCGTCTGTTTCTCAAGTTTCAGACACACCAGTTTCTTATACAACT TCAAGTTCATCTGTTTCTCAAGTTTCAGACACACCGGTTTCTTATACAACTTCAAGTTCG TCCGTTTCTCAAGTTTCAGACACGTCAGTACCTTCTACAAGTTCCAGATCGTCCGTTTCT CAAGTCTCAGACACTCCGGTGCCTTCTACAAGTTCAAGGTCGTCCGTTTCTCAAACATCT AGCTCACTACAGCCCACCACTACATCCTCCCAACGTTTCACCATTTCCACTCATGGAGCG CTTTCTGAAAGTAGTTCTGTTAGCCAACAAGCTTCTGAGATTACTAGCTCAATCAATGCA ACAGCTTCCGAATACCATAGCATCCAGACAACCGCGGCTACTCAATCCACAACTCTATCT TTTACCGACGCAAACAGCAGTTCTGCTTCCGCTCCATTGGAAGTGGCAACGTCTACGCCA ACCCCATCTTCAAAGGCATCCTCTCTGTTGCTTACACCATCAACATCCTCTTTAAGTCAG GTTGCTACAAATACTAATGTACAGACGAGTTTAACAACGGAATCGACGACCGTTTTAGAA CCATCAACGACTAACAGTTCCAGTACGTTTAGTCTGGTCACTTCAAGTGACAACAATTGG TGGATTCCAACTGAGTTAATCACGCAGGCACCAGAAGCTGCATCCACTGCATCTTCTACC GTTGGAGGAACACAAACTATGACTTTGCCCCATGCAATTGCAGCCGCGACACAAGTTCCC GAGCCTGAGGGCTACACCCTAATCACAATAGGGTTCAAAAAAGCTTTGAACTACGAATTT GTTGTATCAGAACCAAAATCATCGGCTCAAATCTTCGGATACTTGCCTGAAGCTCTGAAC ACACCTTTTAAGAACGTATTCACAAACATTACGGTACTACAAATAGTGCCATTACAGGAT GACTCACTCAACTACTTAGTAAGTGTTGCTGAAGTATACTTTCCAACTGCAGAAATAGAG GAGCTGTCAAATCTAATTACCAACTCTTCAAGCGCTTTTTACACGGATGGAATGGGTACA GCAAAATCTATGGCTGCAATGGTTGATTCCTCAATACCGCTAACGGGCCTCTTACACGAT AGTAACAGCAACTCTGGCGGATCTTCGGACGGATCCTCCTCCAGTAATTCGAACTCAGGA TCTTCAGGTTCAGGATCTAATTCGAACTCCGGTGTGTCTTCATCTTCCGGAAATTCCTAT CAAGATGCCGGTACTTTGGAATATTCATCCAAATCTAACTCCAACGTATCCACTTCTAGC AAATCAAAGAAAAAAATCATTGGTTTAGTTATCGGCGTTGTTGTTGGTGGATGCTTATAT ATTTTATTCATGATTTTTGCTTTCAAGTATATCATAAGAAGGCGGATTCAAAGTCAAGAA ATTATCAAGAACCCAGAAATTTCCAGTATCAGTTCAAGTGAATTTGGTGGAGAGAAAAAT TACAATAATGAAAAGAGAATGAGCGTTCAAGAATCCATAACACAATCTATGCGAATTCAA AATTGGATGGATGATAGTTACTATGGTCACGGGTTGACAAATAATGACTCAACTCCAACC AGGCACAATACATCGAGTTCCATACCAAAAATTTCAAGACCAATTGCTAGCCAAAACTCC CTGGGTTGGAACGAAGTTTGA
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues1306
Protein Molecular Weight133112.915
Protein Theoretical pINot Available
Signalling Regions
  • 1-21
Transmembrane Regions
  • 1186-1206
Protein Sequence>Signaling mucin MSB2 MQFPFACLLSTLVISGSLARASPFDFIFGNGTQQAQSQSESQGQVSFTNEASQDSSTTSL VTAYSQGVHSHQSATIVSATISSLPSTWYDASSTSQTSVSYASQESDYAVNQNSWSASTN QLPSTSTTSYYAPTFSTSADFAASSVNAASDVSTASVPIDTSANSIPFTTTSNIETTTSA PLTSDTPLISTSTMSAADNVFSSANPISASLTTTDSSESFDQTSTAGAIPVQSSADFSSS SEILVQSSADFSSPSSPTTTDISLSAAPLQTSESSSFTTASAALPVSSTDVDGSSASPVV SMSAAGQIASSSSTDNPTMSETFSLTSTEVDGSDVSSTVSALLSAPFLQTSTSNSFSIVS PSVSFVPSQSSSDVASSSTANVVSSSFSDIPPQTSTSGSVVSVAQSASALAFQSSTEVYG ASASSTMSSLLSTTSLQSTTLDSSSLASSSASSSDLTDYGVSSTASIPLLSASEQASTSS SFSVVSPSVSFVPSQSSSDVASTSAPSVVSSSFSYTSLQAGGSSMTNPSSSTIVYSSSTG SSEESAASTASATLSGSSSTYMAGNLQSQPPSTSSLLSESQATSTSAVLASSSVSTTSPY TTAGGASTEASSLISSTSAETSQVSYSQSTTALQTSSFASSSTTEGSETSSQGFSTSSVL VQMPSSISSEFSPSQTTTQMNSASSSSQYTISSTGILSQVSDTSVSYTTSSSSVSQVSDT PVSYTTSSSSVSQVSDTPVSYTTSSSSVSQVSDTPVSYTTSSSSVSQVSDTPVSYTTSSS SVSQVSDTSVPSTSSRSSVSQVSDTPVPSTSSRSSVSQTSSSLQPTTTSSQRFTISTHGA LSESSSVSQQASEITSSINATASEYHSIQTTAATQSTTLSFTDANSSSASAPLEVATSTP TPSSKASSLLLTPSTSSLSQVATNTNVQTSLTTESTTVLEPSTTNSSSTFSLVTSSDNNW WIPTELITQAPEAASTASSTVGGTQTMTLPHAIAAATQVPEPEGYTLITIGFKKALNYEF VVSEPKSSAQIFGYLPEALNTPFKNVFTNITVLQIVPLQDDSLNYLVSVAEVYFPTAEIE ELSNLITNSSSAFYTDGMGTAKSMAAMVDSSIPLTGLLHDSNSNSGGSSDGSSSSNSNSG SSGSGSNSNSGVSSSSGNSYQDAGTLEYSSKSNSNVSTSSKSKKKIIGLVIGVVVGGCLY ILFMIFAFKYIIRRRIQSQEIIKNPEISSISSSEFGGEKNYNNEKRMSVQESITQSMRIQ NWMDDSYYGHGLTNNDSTPTRHNTSSSIPKISRPIASQNSLGWNEV
References
External Links
ResourceLink
Saccharomyces Genome Database MSB2
Uniprot IDP32334
Uniprot NameMSB2
General ReferenceNot Available