Tyrosine-protein phosphatase 2 (P29461)

Identification
NameTyrosine-protein phosphatase 2
Synonyms
  • Protein-tyrosine phosphatase 2
  • PTPase 2
Gene NamePTP2
Enzyme ClassNot Available
Biological Properties
General Functionregulation of sporulation
Specific FunctionMajor phosphatase responsible with PTP3 for tyrosine dephosphorylation of MAP kinase HOG1 to inactivate its activity. May also be involved in the regulation of MAP kinase FUS3. May be implicated in the ubiquitin-mediated protein degradation.
Cellular LocationNot Available
SMPDB Pathways
Stress-activated signalling pathways: cell wall stress test 1PW007861 ThumbThumb?image type=greyscaleThumb?image type=simple
Stress-activated signalling pathways: high osmolarity test 1PW002773 ThumbThumb?image type=greyscaleThumb?image type=simple
Stress-activated signalling pathways: low osmolarityPW002515 ThumbThumb?image type=greyscaleThumb?image type=simple
Stress-activated signalling pathways: pheromone stress test 1PW012843 ThumbThumb?image type=greyscaleThumb?image type=simple
Stress-activated signalling pathways: starvation test 1PW003483 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
nucleus
cytoplasm
regulation of protein localization
protein tyrosine phosphatase activity
protein dephosphorylation
inactivation of MAPK activity involved in cell wall organization or biogenesis
inactivation of MAPK activity involved in osmosensory signaling pathway
regulation of sporulation
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>2253 bp ATGGATCGCATAGCACAGCAATATCGTAATGGCAAAAGAGACAATAACGGCAATAGAATG GCTTCTTCCGCTATATCGGAAAAGGGCCACATACAAGTCAATCAAACTAGAACACCTGGT CAAATGCCCGTCTATAGAGGTGAAACTATAAATCTGTCTAACCTTCCCCAAAATCAAATT AAACCGTGCAAAGATTTGGACGACGTTAACATACGGCGGAACAACTCTAATAGGCATTCT AAAATACTTTTACTAGATCTGTGCGCTGGCCCCAATACCAACTCATTTTTAGGCAATACC AATGCTAAGGATATCACAGTTTTATCGTTGCCGCTACCCAGCACTTTGGTGAAAAGGTCG AACTACCCGTTCGAGAACTTACTAAAGAATTACCTTGGATCTGATGAAAAGTATATTGAG TTCACAAAGATCATCAAAGATTATGATATTTTCATTTTCAGTGATTCGTTTAGCAGAATT TCGAGTTGTTTAAAGACAACTTTTTGCCTCATTGAGAAGTTTAAAAAGTTCATCTGCCAT TTTTTTCCATCTCCTTATTTGAAATTCTTTCTTCTCGAAGGCTCTCTGAATGATAGCAAG GCCCCCTCATTAGGAAAAAATAAGAAAAATTGCATCTTGCCCAAATTGGATTTGAACTTG AATGTAAACTTAACTTCAAGGTCAACTTTAAATTTAAGAATAAACATACCTCCACCCAAT GATTCAAATAAAATATTTTTACAGTCTCTGAAAAAGGATCTAATTCATTATTCTCCTAAT TCTTTGCAAAAGTTTTTCCAATTCAATATGCCTGCTGACTTAGCACCTAACGACACGATT TTACCGAATTGGCTAAAATTCTGCTCCGTAAAAGAAAATGAAAAGGTAATATTAAAGAAA CTCTTTAACAATTTTGAAACTTTAGAAAATTTTGAAATGCAAAGATTAGAGAAATGCCTG AAATTCAAGAAAAAGCCTTTACATCAAAAGCAGCTATCACAAAAGCAGAGGGGTCCGCAA TCCACGGATGATTCAAAATTATATTCTTTAACTAGTTTGCAACGACAGTATAAAAGTTCT TTGAAAAGCAACATACAGAAAAATCAAAAGCTAAAATTAATTATACCAAAAAACAACACA TCTTCTTCGCCATCACCATTATCTTCCGATGATACTATAATGTCACCAATAAATGATTAC GAACTTACTGAAGGAATTCAGTCTTTTACTAAGAATAGATATTCTAATATCTTACCTTAC GAACATTCAAGAGTAAAGTTACCTCACTCCCCGAAACCACCTGCAGTTTCTGAAGCATCC ACAACCGAAACTAAAACAGATAAGTCATATCCGATGTGTCCCGTAGATGCAAAAAACCAC TCCTGCAAACCGAACGACTATATCAATGCGAACTATTTGAAGCTCACGCAAATTAATCCT GATTTCAAGTATATTGCTACCCAAGCTCCGCTTCCTTCTACGATGGATGATTTTTGGAAG GTTATTACTTTAAATAAAGTTAAAGTAATAATATCATTGAATTCTGACGATGAATTGAAT TTAAGAAAATGGGATATTTACTGGAATAATCTGTCATATTCCAACCACACTATCAAACTT CAGAACACCTGGGAGAATATTTGCAATATTAATGGCTGTGTTCTCAGAGTCTTTCAAGTC AAGAAAACAGCTCCACAAAATGATAATATCAGTCAAGATTGTGACCTTCCGCATAATGGT GACCTTACTTCCATTACCATGGCTGTATCCGAGCCGTTTATTGTTTACCAATTACAATAC AAGAATTGGTTAGATTCATGCGGCGTAGATATGAATGACATCATTAAACTACACAAAGTC AAAAATTCGTTATTGTTTAACCCGCAAAGTTTTATTACAAGCCTCGAAAAGGATGTTTGC AAGCCTGATTTGATAGATGATAATAATAGTGAGTTACATCTCGATACAGCAAATTCATCG CCACTATTAGTCCATTGTTCTGCAGGGTGTGGAAGAACAGGTGTTTTCGTTACCTTGGAT TTCCTACTAAGTATTCTTTCACCTACAACAAATCACTCAAACAAGATTGATGTTTGGAAT ATGACTCAGGACCTTATCTTTATCATAGTGAATGAATTAAGAAAGCAAAGGATTTCAATG GTACAGAATCTAACTCAATATATCGCTTGTTATGAGGCATTATTAAATTATTTTGCCCTG CAAAAGCAGATAAAGAACGCGTTACCTTGTTAA
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues750
Protein Molecular Weight85867.605
Protein Theoretical pINot Available
Signalling RegionsNot Available
Transmembrane RegionsNot Available
Protein Sequence>Tyrosine-protein phosphatase 2 MDRIAQQYRNGKRDNNGNRMASSAISEKGHIQVNQTRTPGQMPVYRGETINLSNLPQNQI KPCKDLDDVNIRRNNSNRHSKILLLDLCAGPNTNSFLGNTNAKDITVLSLPLPSTLVKRS NYPFENLLKNYLGSDEKYIEFTKIIKDYDIFIFSDSFSRISSCLKTTFCLIEKFKKFICH FFPSPYLKFFLLEGSLNDSKAPSLGKNKKNCILPKLDLNLNVNLTSRSTLNLRINIPPPN DSNKIFLQSLKKDLIHYSPNSLQKFFQFNMPADLAPNDTILPNWLKFCSVKENEKVILKK LFNNFETLENFEMQRLEKCLKFKKKPLHQKQLSQKQRGPQSTDDSKLYSLTSLQRQYKSS LKSNIQKNQKLKLIIPKNNTSSSPSPLSSDDTIMSPINDYELTEGIQSFTKNRYSNILPY EHSRVKLPHSPKPPAVSEASTTETKTDKSYPMCPVDAKNHSCKPNDYINANYLKLTQINP DFKYIATQAPLPSTMDDFWKVITLNKVKVIISLNSDDELNLRKWDIYWNNLSYSNHTIKL QNTWENICNINGCVLRVFQVKKTAPQNDNISQDCDLPHNGDLTSITMAVSEPFIVYQLQY KNWLDSCGVDMNDIIKLHKVKNSLLFNPQSFITSLEKDVCKPDLIDDNNSELHLDTANSS PLLVHCSAGCGRTGVFVTLDFLLSILSPTTNHSNKIDVWNMTQDLIFIIVNELRKQRISM VQNLTQYIACYEALLNYFALQKQIKNALPC
References
External Links
ResourceLink
Saccharomyces Genome Database PTP2
Uniprot IDP29461
Uniprot NamePTP2
General ReferenceNot Available