| Identification |
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| Name | Asparaginyl-tRNA synthetase, mitochondrial |
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| Synonyms | - Asparagine--tRNA ligase
- AsnRS
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| Gene Name | SLM5 |
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| Enzyme Class | |
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| Biological Properties |
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| General Function | Involved in nucleotide binding |
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| Specific Function | ATP + L-asparagine + tRNA(Asn) = AMP + diphosphate + L-asparaginyl-tRNA(Asn) |
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| Cellular Location | Mitochondrion matrix |
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| SMPDB Pathways | Not Available |
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| KEGG Pathways | Not Available |
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| SMPDB Reactions | Not Available |
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| KEGG Reactions | |
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| Metabolites | | YMDB ID | Name | View |
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| YMDB00097 | Adenosine monophosphate | Show | | YMDB00109 | Adenosine triphosphate | Show | | YMDB00219 | Pyrophosphate | Show | | YMDB00226 | L-Asparagine | Show |
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| GO Classification | | Component |
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| cell part | | intracellular part | | cytoplasm | | Function |
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| adenyl ribonucleotide binding | | aspartate-tRNA ligase activity | | ATP binding | | asparagine-tRNA ligase activity | | ligase activity, forming carbon-oxygen bonds | | ligase activity, forming aminoacyl-tRNA and related compounds | | aminoacyl-tRNA ligase activity | | catalytic activity | | nucleotide binding | | ligase activity | | binding | | nucleoside binding | | purine nucleoside binding | | nucleic acid binding | | adenyl nucleotide binding | | Process |
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| aspartyl-tRNA aminoacylation | | asparaginyl-tRNA aminoacylation | | metabolic process | | cellular macromolecule metabolic process | | macromolecule metabolic process | | RNA metabolic process | | ncRNA metabolic process | | tRNA metabolic process | | biosynthetic process | | tRNA aminoacylation | | tRNA aminoacylation for protein translation | | macromolecule biosynthetic process | | cellular macromolecule biosynthetic process | | translation |
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| Gene Properties |
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| Chromosome Location | chromosome 3 |
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| Locus | YCR024C |
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| Gene Sequence | >1479 bp
ATGTTTCATGCTTTCACCTTCCTTAAAGGTGGTAGATTTTACTCTTCACTAACAGTTAAA
TCATTGTACGAGCAGGTACACCATACTAGCCATGATCCCATTTCAATTAATGGATGGATC
AAATCCATAAGACTATTAAAACGTATAGCGTTTTTGGATTTACAAGATGGGACTTCTGTG
AACCCATTAAGAATAGTTATTCCACTCACAAATACTGATGAAGTACAGTTCCTAAAAATT
CTGAAAACTGGTCAAACTTTATCTATATCTAATGCTACCTGGCAAAGCACCCCTAATAGA
AAACAACCTTTTGAATTGCAAATCAAAAATCCTGTCAAGTCAATTAAACTTGTGGGTCCC
GTTTCAGAAAACTATCCATTACAAAAGAAATATCAAACCTTACGTTATTTAAGGTCCTTA
CCTACACTAAAATACAGAACCGCTTACTTAAGTGCAATTTTACGGTTAAGATCCTTTGTA
GAATTCCAGTTCATGCTATATTTCCAGAAAAACCACTTCACCAAAGTTTCACCACCAATA
TTAACTTCAAACGATTGTGAAGGTGCCGGCGAGTTGTTTCAAGTCTCCACCAATACGTCG
CCAACTGCATCCTCGTACTTTGGGAAGCCGACTTATTTGACTGTGTCCACTCAATTGCAC
TTGGAAATTTTAGCGTTATCACTGTCAAGGTGTTGGACGTTATCTCCTTGCTTTAGAGCC
GAAAAGAGTGATACTCCAAGACACCTTTCGGAGTTTTGGATGCTTGAAGTGGAAATGTGC
TTTGTTAATAGCGTCAACGAGCTAACATCGTTTGTTGAGACTACAATAAAACACATAATT
AAAGCTTGTATAGATAACCAACAAGAACTCTTGCCGAAGCAATTTATCTCTTCACAAGAA
AATAATGCATCGTCAGAGCTATCAATAAATCAAGAGACACAACAAATTAAAACACGATGG
GAAGATTTAATAAATGAAAAATGGCACAATATAACGTATACCAATGCAATAGAAATTCTC
AAGAAACGCCACAATGAAGTTTCACACTTTAAGTATGAACCTAAATGGGGACAGCCTTTG
CAAACTGAACATGAAAAATTTTTAGCCGGAGAGTATTTTAAGTCCCCAGTTTTCGTTACC
GACTATCCACGTCTTTGTAAACCATTCTACATGAAACAAAATTCCACTCCTGACGATACT
GTTGGATGCTTTGATCTACTGGTTCCTGGAATGGGTGAAATAATTGGTGGGAGTTTAAGG
GAAGATGACTATGACAAGTTATGTAGAGAAATGAAAGCACGCGGGATGAATAGATCTGGA
GAATTGGACTGGTATGTTTCTCTGAGAAAAGAAGGAAGTGCACCACACGGAGGCTTTGGT
CTAGGGTTTGAGAGATTTATCTCATACTTATATGGCAACCATAATATAAAGGATGCCATA
CCCTTTTATAGAACATCTGCAGAATCCATCGATTTTTGA |
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| Protein Properties |
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| Pfam Domain Function | |
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| Protein Residues | 492 |
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| Protein Molecular Weight | 56784.39844 |
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| Protein Theoretical pI | 8.64 |
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| Signalling Regions | |
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| Transmembrane Regions | |
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| Protein Sequence | >Asparaginyl-tRNA synthetase, mitochondrial
MFHAFTFLKGGRFYSSLTVKSLYEQVHHTSHDPISINGWIKSIRLLKRIAFLDLQDGTSV
NPLRIVIPLTNTDEVQFLKILKTGQTLSISNATWQSTPNRKQPFELQIKNPVKSIKLVGP
VSENYPLQKKYQTLRYLRSLPTLKYRTAYLSAILRLRSFVEFQFMLYFQKNHFTKVSPPI
LTSNDCEGAGELFQVSTNTSPTASSYFGKPTYLTVSTQLHLEILALSLSRCWTLSPCFRA
EKSDTPRHLSEFWMLEVEMCFVNSVNELTSFVETTIKHIIKACIDNQQELLPKQFISSQE
NNASSELSINQETQQIKTRWEDLINEKWHNITYTNAIEILKKRHNEVSHFKYEPKWGQPL
QTEHEKFLAGEYFKSPVFVTDYPRLCKPFYMKQNSTPDDTVGCFDLLVPGMGEIIGGSLR
EDDYDKLCREMKARGMNRSGELDWYVSLRKEGSAPHGGFGLGFERFISYLYGNHNIKDAI
PFYRTSAESIDF |
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| References |
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| External Links | |
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| General Reference | - Bolle, P. A., Gilliquet, V., Berben, G., Dumont, J., Hilger, F. (1992). "The complete sequence of K3B, a 7.9 kb fragment between PGK1 and CRY1 on chromosome III, reveals the presence of seven open reading frames." Yeast 8:205-213.1574926
- Oliver, S. G., van der Aart, Q. J., Agostoni-Carbone, M. L., Aigle, M., Alberghina, L., Alexandraki, D., Antoine, G., Anwar, R., Ballesta, J. P., Benit, P., et, a. l. .. (1992). "The complete DNA sequence of yeast chromosome III." Nature 357:38-46.1574125
- Landrieu, I., Vandenbol, M., Hartlein, M., Portetelle, D. (1997). "Mitochondrial asparaginyl-tRNA synthetase is encoded by the yeast nuclear gene YCR24c." Eur J Biochem 243:268-273.9030748
- Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106
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