| Identification |
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| Name | 5',5'''-P-1,P-4-tetraphosphate phosphorylase 2 |
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| Synonyms | - ATP adenylyltransferase
- Ap4A phosphorylase II
- AP,A phosphorylase
- Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase
- AP-4-A phosphorylase
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| Gene Name | APA2 |
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| Enzyme Class | |
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| Biological Properties |
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| General Function | Involved in ATP adenylyltransferase activity |
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| Specific Function | Sustains the catabolism of Np-4-N' nucleotides, rather than their synthesis |
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| Cellular Location | Not Available |
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| SMPDB Pathways | Not Available |
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| KEGG Pathways | |
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| SMPDB Reactions | Not Available |
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| KEGG Reactions | |
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| Metabolites | | YMDB ID | Name | View |
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| YMDB00097 | Adenosine monophosphate | Show | | YMDB00109 | Adenosine triphosphate | Show | | YMDB00225 | P1,P4-Bis(5'-adenosyl) tetraphosphate | Show | | YMDB00261 | Guanosine monophosphate | Show | | YMDB00558 | GTP | Show | | YMDB00590 | P(1),P(4)-bis(5'-adenosyl) tetraphosphate | Show | | YMDB00862 | hydron | Show | | YMDB00907 | phosphate | Show | | YMDB00914 | ADP | Show |
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| GO Classification | | Component |
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| Not Available | | Function |
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| catalytic activity | | transferase activity | | transferase activity, transferring phosphorus-containing groups | | binding | | nucleoside binding | | purine nucleoside binding | | adenyl nucleotide binding | | adenyl ribonucleotide binding | | ATP binding | | nucleotidyltransferase activity | | adenylyltransferase activity | | ATP adenylyltransferase activity | | Process |
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| Not Available |
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| Gene Properties |
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| Chromosome Location | chromosome 4 |
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| Locus | YDR530C |
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| Gene Sequence | >978 bp
ATGATTGAAGAGAATTTGAAACAGAAAATCCACGATAAGTTCGTTGCAGCCAAAAAGAAT
GGGCATCTGAAAGTAACGCATGCAGAATCCAAGAAGTTGAAAGATCCTCAAACGACGACA
CAATATTGGGTGACATTTGCTCCATCTTTGGCACTTAAGCCAGACGCTAACAAGAATAGC
GATTCAAAGGCGGAGGACCCGTTCGCCAATCCCGACGAAGAACTAGTGGTGACTGAAGAT
CTAAATGGTGACGGAGAATATAAGCTGCTACTCAACAAATTTCCTGTGGTCCCTGAACAT
AGTCTCCTAGTGACAAGCGAGTTTAAAGACCAGAGATCTGCTTTGACGCCAAGTGACTTG
ATGACTGCTTATAATGTGCTCTGTTCTCTCCAAGGAGACAAGGACGATGATGTCACTTGT
GAAAGGTATCTGGTCTTTTATAATTGTGGACCTCATAGCGGTTCCTCACAAGATCACAAA
CACTTGCAGATCATGCAAATGCCTGAAAAATTTATACCTTTTCAGGACGTATTGTGCAAC
GGAAAGGATCATTTCTTGCCCACCTTCAACGCAGAGCCATTACAAGATGATAAGGTTTCC
TTTGCTCATTTCGTCTTGCCGCTGCCGGAATCGTCTGATCAAGTGGACGAAGATCTTCTT
GCTATGTGTTACGTATCTTTGATGCAGAGAGCACTTACATTTTTCCAAGATTGGACCAAT
GAGTCTCCGGAGTTGACCAAGTCATACAATGTGCTACTGACCAAGAAATGGATCTGTGTA
GTTCCAAGATCGCATGCCAAGAGTGGACCGCCATTGATGTTAAACATTAACTCCACGGGG
TACTGTGGTATGATCCTCGTTAAAGACAGAGAAAAACTAGAGAACCTCACTGAAGATCCT
CATCTTGTGGACAAGTCGTTACTGCAATGCGGTTTCCCCAACACAGCAGGCCAAAAACCA
ACAGAGTATCACTATTAA |
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| Protein Properties |
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| Pfam Domain Function | |
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| Protein Residues | 325 |
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| Protein Molecular Weight | 36840.5 |
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| Protein Theoretical pI | 5.23 |
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| Signalling Regions | |
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| Transmembrane Regions | |
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| Protein Sequence | >5',5'''-P-1,P-4-tetraphosphate phosphorylase 2
MIEENLKQKIHDKFVAAKKNGHLKVTHAESKKLKDPQTTTQYWVTFAPSLALKPDANKNS
DSKAEDPFANPDEELVVTEDLNGDGEYKLLLNKFPVVPEHSLLVTSEFKDQRSALTPSDL
MTAYNVLCSLQGDKDDDVTCERYLVFYNCGPHSGSSQDHKHLQIMQMPEKFIPFQDVLCN
GKDHFLPTFNAEPLQDDKVSFAHFVLPLPESSDQVDEDLLAMCYVSLMQRALTFFQDWTN
ESPELTKSYNVLLTKKWICVVPRSHAKSGPPLMLNINSTGYCGMILVKDREKLENLTEDP
HLVDKSLLQCGFPNTAGQKPTEYHY |
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| References |
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| External Links | |
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| General Reference | - Plateau, P., Fromant, M., Schmitter, J. M., Blanquet, S. (1990). "Catabolism of bis(5'-nucleosidyl) tetraphosphates in Saccharomyces cerevisiae." J Bacteriol 172:6892-6899.2174863
- Jacq, C., Alt-Morbe, J., Andre, B., Arnold, W., Bahr, A., Ballesta, J. P., Bargues, M., Baron, L., Becker, A., Biteau, N., Blocker, H., Blugeon, C., Boskovic, J., Brandt, P., Bruckner, M., Buitrago, M. J., Coster, F., Delaveau, T., del Rey, F., Dujon, B., Eide, L. G., Garcia-Cantalejo, J. M., Goffeau, A., Gomez-Peris, A., Zaccaria, P., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome IV." Nature 387:75-78.9169867
- Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106
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