Identification |
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Name | G1/S-specific cyclin CLN2 |
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Synonyms | Not Available |
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Gene Name | CLN2 |
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Enzyme Class | Not Available |
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Biological Properties |
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General Function | regulation of cyclin-dependent protein serine/threonine kinase activity |
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Specific Function | Essential for the control of the cell cycle at the G1/S (start) transition. Interacts with the CDC28 protein kinase to form MPF. |
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Cellular Location | Not Available |
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SMPDB Pathways | Stress-activated signalling pathways: pheromone stress test 1 | PW012843 | |
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KEGG Pathways | Not Available |
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SMPDB Reactions | Not Available |
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KEGG Reactions | Not Available |
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Metabolites | |
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GO Classification | Function |
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nucleus | cyclin-dependent protein kinase holoenzyme complex | cytoplasm | cell division | cyclin-dependent protein serine/threonine kinase regulator activity | regulation of cyclin-dependent protein serine/threonine kinase activity | re-entry into mitotic cell cycle after pheromone arrest |
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Gene Properties |
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Chromosome Location | Not Available |
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Locus | |
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Gene Sequence | >1638 bp
ATGGCTAGTGCTGAACCAAGACCCCGTATGGGACTCGTCATCAATGCTAAACCGGACTAC
TATCCGATTGAGCTATCTAATGCAGAATTACTTTCTCACTTCGAAATGCTGCAAGAATAC
CACCAAGAAATCTCCACCAATGTTATTGCTCAATCATGTAAGTTCAAACCTAATCCAAAA
CTAATAGACCAGCAGCCTGAAATGAACCCCGTGGAAACAAGGTCCAACATTATCACTTTT
TTGTTCGAGCTGTCTGTGGTCACTCGAGTGACAAATGGTATTTTTTTTCATTCAGTTAGA
TTATATGACCGCTATTGTTCCAAGAGAATCGTGTTACGGGACCAAGCCAAATTGGTTGTC
GCTACTTGTCTCTGGTTGGCTGCTAAAACTTGGGGCGGTTGTAATCACATCATCAATAAT
GTAGTCATCCCTACTGGCGGAAGATTTTATGGTCCCAACCCAAGGGCACGTATACCTCGA
CTCTCTGAACTAGTTCATTACTGTGGTGATGGTCAGGTCTTTGATGAATCAATGTTTTTA
CAAATGGAAAGACATATACTAGACACTTTAAATTGGAACATTTATGAACCAATGATCAAT
GATTACGTTTTAAATGTTGATGAAAATTGTTTGATGCAATACGAACTTTATGAAAATCAA
GTTACTTATGACAAACAATGCTCTGAAAAACGTCAGTCTCAATTATCCCAGGATAGTGAT
GCCACTGTAGACGAGAGGCCCTACCAAAACGAAGAAGAAGAAGAAGAAGACTTAAAACTA
AAGATCAAGTTGATTAATTTGAAAAAATTCTTGATTGATGTATCCGCGTGGCAGTACGAC
TTACTTAGATATGAACTTTTCGAAGTATCGCACGGCATATTCTCCATTATCAATCAATTC
ACCAATCAAGACCACGGTCCTTTTTTAATGACTCCAATGACATCAGAAAGCAAAAATGGT
GAAATTTTGAGTACCTTAATGAACGGCATTGTTTCCATTCCTAACTCCTTGATGGAAGTG
TATAAAACGGTCAATGGTGTTCTACCCTTCATTAATCAAGTGAAAGAATATCACTTGGAT
CTACAAAGAAAACTGCAAATTGCATCCAACTTGAACATTTCGAGAAAGCTTACCATATCA
ACCCCATCATGCTCTTTCGAAAATTCAAATAGCACATCCATTCCTTCGCCCGCTTCCTCA
TCTCAAAGCCACACTCCAATGAGAAACATGAGCTCACTCTCTGATAACAGCGTTTTCAGC
CGGAATATGGAACAATCATCACCAATCACTCCAAGTATGTACCAATTTGGTCAGCAGCAG
TCAAACAGTATATGTGGTAGCACCGTTAGTGTGAATAGTCTGGTGAATACAAATAACAAA
CAAAGGATCTACGAACAAATCACGGGTCCTAACAGCAATAACGCAACCAATGATTATATT
GATTTGCTAAACCTAAATGAGTCTAACAAGGAAAACCAAAATCCCGCAACGGCGCATTAC
CTCAATGGGGGCCCACCCAAGACAAGCTTCATTAACCATGGAATGTTCCCCTCGCCAACT
GGGACCATAAATAGCGGTAAATCTAGCAGTGCCTCATCTTTAATTTCTTTTGGTATGGGC
AATACCCAAGTAATATAG |
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Protein Properties |
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Pfam Domain Function | Not Available |
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Protein Residues | 545 |
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Protein Molecular Weight | 61696.1 |
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Protein Theoretical pI | Not Available |
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Signalling Regions | Not Available |
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Transmembrane Regions | Not Available |
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Protein Sequence | >G1/S-specific cyclin CLN2
MASAEPRPRMGLVINAKPDYYPIELSNAELLSHFEMLQEYHQEISTNVIAQSCKFKPNPK
LIDQQPEMNPVETRSNIITFLFELSVVTRVTNGIFFHSVRLYDRYCSKRIVLRDQAKLVV
ATCLWLAAKTWGGCNHIINNVVIPTGGRFYGPNPRARIPRLSELVHYCGDGQVFDESMFL
QMERHILDTLNWNIYEPMINDYVLNVDENCLMQYELYENQVTYDKQCSEKRQSQLSQDSD
ATVDERPYQNEEEEEEDLKLKIKLINLKKFLIDVSAWQYDLLRYELFEVSHGIFSIINQF
TNQDHGPFLMTPMTSESKNGEILSTLMNGIVSIPNSLMEVYKTVNGVLPFINQVKEYHLD
LQRKLQIASNLNISRKLTISTPSCSFENSNSTSIPSPASSSQSHTPMRNMSSLSDNSVFS
RNMEQSSPITPSMYQFGQQQSNSICGSTVSVNSLVNTNNKQRIYEQITGPNSNNATNDYI
DLLNLNESNKENQNPATAHYLNGGPPKTSFINHGMFPSPTGTINSGKSSSASSLISFGMG
NTQVI |
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References |
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External Links | Resource | Link |
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Saccharomyces Genome Database | CLN2 | Uniprot ID | P20438 | Uniprot Name | CLN2 |
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General Reference | Not Available |
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