Cell division control protein 42 (P19073)

Identification
NameCell division control protein 42
Synonyms
  • Suppressor of RHO3 protein 2
Gene NameCDC42
Enzyme ClassNot Available
Biological Properties
General Functionsmall GTPase mediated signal transduction
Specific FunctionInvolved in development of cell polarity during the cell division cycle, and essential for bud emergence. Affects signaling in the pheromone-response pathway through the STE20 protein kinase. Negatively regulated by the GTPase-activating proteins RGA1, BEM3, and BEM4.
Cellular LocationNot Available
SMPDB Pathways
Stress-activated signalling pathways: high osmolarity 1469654356PW002970 ThumbThumb?image type=greyscaleThumb?image type=simple
Stress-activated signalling pathways: high osmolarity test 1PW002773 ThumbThumb?image type=greyscaleThumb?image type=simple
Stress-activated signalling pathways: pheromone stress test 1PW012843 ThumbThumb?image type=greyscaleThumb?image type=simple
Stress-activated signalling pathways: starvation test 1PW003483 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
nuclear membrane
GTP binding
septin ring
GTPase activity
budding cell apical bud growth
cellular bud tip
budding cell isotropic bud growth
incipient cellular bud site
establishment of cell polarity
mating projection tip
regulation of exocyst localization
positive regulation of exocytosis
regulation of vacuole fusion, non-autophagic
regulation of cell morphogenesis
small GTPase mediated signal transduction
regulation of initiation of mating projection growth
invasive growth in response to glucose limitation
plasma membrane
regulation of exit from mitosis
septin ring organization
conjugation with cellular fusion
cell cycle
positive regulation of pseudohyphal growth
pheromone-dependent signal transduction involved in conjugation with cellular fusion
fungal-type vacuole membrane
cellular bud neck
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>576 bp ATGCAAACGCTAAAGTGTGTTGTTGTCGGTGATGGTGCTGTTGGGAAAACGTGCCTTCTA ATCTCCTATACAACGAATCAATTTCCAGCCGACTATGTTCCAACAGTGTTCGATAACTAT GCGGTGACTGTGATGATTGGTGATGAACCATATACGTTAGGTTTGTTTGATACGGCCGGT CAAGAAGATTACGATCGATTGAGACCCTTGTCATATCCTTCTACTGATGTATTTTTGGTT TGTTTCAGTGTTATTTCCCCACCCTCTTTTGAAAACGTTAAAGAAAAATGGTTCCCTGAA GTACATCACCATTGTCCAGGTGTACCATGCCTGGTCGTCGGTACGCAGATTGATCTAAGG GATGACAAGGTAATCATCGAGAAGTTGCAAAGACAAAGATTACGTCCGATTACATCAGAA CAAGGTTCCAGGTTAGCAAGAGAACTGAAAGCAGTAAAATATGTCGAGTGTTCGGCACTA ACACAACGCGGTTTGAAGAATGTATTCGATGAAGCTATCGTGGCCGCCTTGGAGCCTCCT GTTATCAAGAAAAGTAAAAAATGTGCAATTTTGTAG
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues191
Protein Molecular Weight21322.54
Protein Theoretical pINot Available
Signalling RegionsNot Available
Transmembrane RegionsNot Available
Protein Sequence>Cell division control protein 42 MQTLKCVVVGDGAVGKTCLLISYTTNQFPADYVPTVFDNYAVTVMIGDEPYTLGLFDTAG QEDYDRLRPLSYPSTDVFLVCFSVISPPSFENVKEKWFPEVHHHCPGVPCLVVGTQIDLR DDKVIIEKLQRQRLRPITSEQGSRLARELKAVKYVECSALTQRGLKNVFDEAIVAALEPP VIKKSKKCAIL
References
External Links
ResourceLink
Saccharomyces Genome Database CDC42
Uniprot IDP19073
Uniprot NameCDC42
General ReferenceNot Available