| Identification |
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| Name | Cell division control protein 42 |
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| Synonyms | - Suppressor of RHO3 protein 2
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| Gene Name | CDC42 |
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| Enzyme Class | Not Available |
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| Biological Properties |
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| General Function | small GTPase mediated signal transduction |
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| Specific Function | Involved in development of cell polarity during the cell division cycle, and essential for bud emergence. Affects signaling in the pheromone-response pathway through the STE20 protein kinase. Negatively regulated by the GTPase-activating proteins RGA1, BEM3, and BEM4. |
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| Cellular Location | Not Available |
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| SMPDB Pathways | | Stress-activated signalling pathways: high osmolarity 1469654356 | PW002970 |    | | Stress-activated signalling pathways: high osmolarity test 1 | PW002773 |    | | Stress-activated signalling pathways: pheromone stress test 1 | PW012843 |    | | Stress-activated signalling pathways: starvation test 1 | PW003483 |    |
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| KEGG Pathways | Not Available |
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| SMPDB Reactions | Not Available |
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| KEGG Reactions | Not Available |
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| Metabolites | |
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| GO Classification | | Function |
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| septin ring organization | | conjugation with cellular fusion | | cell cycle | | positive regulation of pseudohyphal growth | | pheromone-dependent signal transduction involved in conjugation with cellular fusion | | fungal-type vacuole membrane | | cellular bud neck | | nuclear membrane | | GTP binding | | septin ring | | GTPase activity | | budding cell apical bud growth | | cellular bud tip | | budding cell isotropic bud growth | | incipient cellular bud site | | establishment of cell polarity | | mating projection tip | | positive regulation of exocytosis | | regulation of exocyst localization | | regulation of cell morphogenesis | | regulation of vacuole fusion, non-autophagic | | regulation of initiation of mating projection growth | | small GTPase mediated signal transduction | | invasive growth in response to glucose limitation | | plasma membrane | | regulation of exit from mitosis |
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| Gene Properties |
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| Chromosome Location | Not Available |
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| Locus | |
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| Gene Sequence | >576 bp
ATGCAAACGCTAAAGTGTGTTGTTGTCGGTGATGGTGCTGTTGGGAAAACGTGCCTTCTA
ATCTCCTATACAACGAATCAATTTCCAGCCGACTATGTTCCAACAGTGTTCGATAACTAT
GCGGTGACTGTGATGATTGGTGATGAACCATATACGTTAGGTTTGTTTGATACGGCCGGT
CAAGAAGATTACGATCGATTGAGACCCTTGTCATATCCTTCTACTGATGTATTTTTGGTT
TGTTTCAGTGTTATTTCCCCACCCTCTTTTGAAAACGTTAAAGAAAAATGGTTCCCTGAA
GTACATCACCATTGTCCAGGTGTACCATGCCTGGTCGTCGGTACGCAGATTGATCTAAGG
GATGACAAGGTAATCATCGAGAAGTTGCAAAGACAAAGATTACGTCCGATTACATCAGAA
CAAGGTTCCAGGTTAGCAAGAGAACTGAAAGCAGTAAAATATGTCGAGTGTTCGGCACTA
ACACAACGCGGTTTGAAGAATGTATTCGATGAAGCTATCGTGGCCGCCTTGGAGCCTCCT
GTTATCAAGAAAAGTAAAAAATGTGCAATTTTGTAG |
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| Protein Properties |
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| Pfam Domain Function | Not Available |
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| Protein Residues | 191 |
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| Protein Molecular Weight | 21322.54 |
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| Protein Theoretical pI | Not Available |
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| Signalling Regions | Not Available |
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| Transmembrane Regions | Not Available |
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| Protein Sequence | >Cell division control protein 42
MQTLKCVVVGDGAVGKTCLLISYTTNQFPADYVPTVFDNYAVTVMIGDEPYTLGLFDTAG
QEDYDRLRPLSYPSTDVFLVCFSVISPPSFENVKEKWFPEVHHHCPGVPCLVVGTQIDLR
DDKVIIEKLQRQRLRPITSEQGSRLARELKAVKYVECSALTQRGLKNVFDEAIVAALEPP
VIKKSKKCAIL |
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| References |
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| External Links | | Resource | Link |
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| Saccharomyces Genome Database | CDC42 | | Uniprot ID | P19073 | | Uniprot Name | CDC42 |
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| General Reference | Not Available |
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