Nitrogen regulatory protein GLN3 (P18494)

Identification
NameNitrogen regulatory protein GLN3
SynonymsNot Available
Gene NameGLN3
Enzyme ClassNot Available
Biological Properties
General Functionpositive regulation of transcription from RNA polymerase II promoter
Specific FunctionPositive nitrogen regulatory protein. Required for the activation of transcription of a number of genes (including the allantoin pathway genes) in response to the replacement of glutamine by glutamate as source of nitrogen. Binds the nitrogen upstream activation sequence of GLN1, the gene encoding glutamine synthetase. URE2 may catalytically inactivate GLN3 in response to an increase in the intracellular concentration of glutamine.
Cellular LocationNot Available
SMPDB Pathways
TOR signalling pathway: Rapamycin based repressionPW002514 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
cell differentiation
nitrate assimilation
nitrogen catabolite activation of transcription from RNA polymerase II promoter
zinc ion binding
cytosol
nucleus
positive regulation of transcription from RNA polymerase II promoter
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor complex
chromatin binding
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>2193 bp ATGCAAGACGACCCCGAAAATTCGAAGCTGTACGACCTGCTGAATAGTCATCTGGACGTG CATGGTCGAAGTAATGAAGAGCCGAGACAAACTGGTGACAGTAGGAGCCAGAGTAGTGGC AACACCGGTGAAAACGAGGAGGATATAGCATTTGCCAGTGGATTAAACGGCGGCACATTC GACTCAATGCTGGAGGCACTGCCCGATGATTTATATTTTACGGACTTCGTGTCTCCTTTT ACAGCAGCTGCCACGACCAGCGTGACTACTAAGACGGTCAAGGACACCACACCAGCTACC AATCATATGGATGATGATATTGCGATGTTTGATTCACTTGCCACAACTCAGCCCATCGAC ATAGCCGCATCCAACCAACAAAATGGTGAAATTGCACAACTTTGGGACTTTAACGTGGAC CAATTCAACATGACGCCCAGCAACTCGAGCGGTTCAGCTACTATTAGTGCTCCTAACAGC TTTACTTCCGACATACCGCAATACAACCACGGTTCCCTCGGCAACAGCGTCTCCAAATCC TCACTGTTCCCGTATAATTCCAGCACGTCCAACAGCAACATCAACCAGCCATCTATCAAT AACAACTCAAATACTAATGCGCAGTCCCACCATTCCTTCAACATCTACAAACTACAAAAC AACAACTCATCTTCATCCGCTATGAACATTACCAATAATAATAATAGCAACAATAGTAAT ATCCAGCATCCTTTTCTGAAGAAGAGCGATTCGATAGGATTATCTTCATCCAACACAACA AATTCTGTAAGAAAAAACTCACTTATCAAGCCAATGTCGTCCACGTCCCTGGCCAATTTC AAAAGAGCTGCCTCAGTATCTTCCAGTATATCCAATATGGAACCATCAGGACAAAATAAA AAACCTCTGATACAATGTTTCAATTGTAAAACTTTCAAGACACCGCTTTGGAGGAGAAGC CCAGAGGGGAATACTCTTTGCAATGCCTGCGGTCTTTTCCAGAAATTACATGGTACCATG AGGCCATTATCCTTAAAATCGGACGTTATCAAAAAGAGGATTTCAAAGAAGAGAGCCAAA CAAACGGACCCAAACATTGCACAAAATACTCCAAGTGCACCTGCAACTGCCTCAACTTCA GTAACCACTACAAATGCTAAACCCATACGATCGAGGAAAAAATCACTACAACAAAACTCT TTATCTAGAGTGATACCTGAAGAAATCATTAGAGACAACATCGGTAATACTAATAATATC CTTAATGTAAATAGGGGAGGCTATAACTTCAACTCAGTCCCCTCCCCGGTCCTCATGAAC AGCCAATCGTATAATAGTAGTAACGCAAATTTTAATGGAGCAAGCAATGCAAATTTGAAT TCTAATAACTTAATGCGTCACAATTCGAACACTGTTACTCCTAATTTTAGAAGGTCTTCA AGACGAAGTAGTACTTCATCGAACACCTCAAGTTCCAGTAAATCTTCATCCAGATCTGTT GTTCCGATATTACCAAAACCTTCACCTAATAGCGCTAATTCACAGCAGTTCAACATGAAC ATGAACCTAATGAACACAACAAATAATGTAAGTGCAGGAAATAGTGTCGCATCCTCACCA AGAATTATATCGTCCGCAAACTTTAACTCAAATAGTCCTCTACAGCAGAATCTATTATCA AATTCTTTCCAACGTCAAGGAATGAATATACCAAGAAGAAAGATGTCGCGCAATGCATCG TACTCCTCATCGTTTATGGCTGCGTCTTTGCAACAACTGCACGAACAGCAACAAGTGGAC GTGAATTCCAACACAAACACGAATTCGAATAGACAGAATTGGAATTCAAGCAATAGCGTT TCAACAAATTCAAGATCATCAAATTTTGTCTCTCAAAAGCCAAATTTTGATATTTTTAAT ACTCCTGTAGATTCACCGAGTGTCTCAAGACCTTCTTCAAGAAAATCACATACCTCATTG TTATCACAACAATTGCAGAACTCGGAGTCGAATTCGTTTATCTCAAATCACAAATTTAAC AATAGATTATCAAGTGACTCTACTTCACCTATAAAATATGAAGCAGATGTGAGTGCAGGC GGAAAGATCAGTGAGGATAATTCCACAAAAGGATCTTCTAAAGAAAGTTCAGCAATTGCT GACGAATTGGATTGGTTAAAATTTGGTATATGA
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues730
Protein Molecular Weight79381.825
Protein Theoretical pINot Available
Signalling RegionsNot Available
Transmembrane RegionsNot Available
Protein Sequence>Nitrogen regulatory protein GLN3 MQDDPENSKLYDLLNSHLDVHGRSNEEPRQTGDSRSQSSGNTGENEEDIAFASGLNGGTF DSMLEALPDDLYFTDFVSPFTAAATTSVTTKTVKDTTPATNHMDDDIAMFDSLATTQPID IAASNQQNGEIAQLWDFNVDQFNMTPSNSSGSATISAPNSFTSDIPQYNHGSLGNSVSKS SLFPYNSSTSNSNINQPSINNNSNTNAQSHHSFNIYKLQNNNSSSSAMNITNNNNSNNSN IQHPFLKKSDSIGLSSSNTTNSVRKNSLIKPMSSTSLANFKRAASVSSSISNMEPSGQNK KPLIQCFNCKTFKTPLWRRSPEGNTLCNACGLFQKLHGTMRPLSLKSDVIKKRISKKRAK QTDPNIAQNTPSAPATASTSVTTTNAKPIRSRKKSLQQNSLSRVIPEEIIRDNIGNTNNI LNVNRGGYNFNSVPSPVLMNSQSYNSSNANFNGASNANLNSNNLMRHNSNTVTPNFRRSS RRSSTSSNTSSSSKSSSRSVVPILPKPSPNSANSQQFNMNMNLMNTTNNVSAGNSVASSP RIISSANFNSNSPLQQNLLSNSFQRQGMNIPRRKMSRNASYSSSFMAASLQQLHEQQQVD VNSNTNTNSNRQNWNSSNSVSTNSRSSNFVSQKPNFDIFNTPVDSPSVSRPSSRKSHTSL LSQQLQNSESNSFISNHKFNNRLSSDSTSPIKYEADVSAGGKISEDNSTKGSSKESSAIA DELDWLKFGI
References
External Links
ResourceLink
Saccharomyces Genome Database GLN3
Uniprot IDP18494
Uniprot NameGLN3
General ReferenceNot Available