| Identification |
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| Name | Galactose transporter |
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| Synonyms | |
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| Gene Name | GAL2 |
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| Enzyme Class | Not Available |
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| Biological Properties |
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| General Function | Involved in transmembrane transporter activity |
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| Specific Function | GAL2 is a facilitated diffusion transporter required for both the high-affinity galactokinase-dependent and low-affinity galactokinase-independent galactose transport processes |
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| Cellular Location | Membrane; Multi-pass membrane protein |
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| SMPDB Pathways | Not Available |
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| KEGG Pathways | Not Available |
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| SMPDB Reactions | Not Available |
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| KEGG Reactions | Not Available |
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| Metabolites | | YMDB ID | Name | View |
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| YMDB00072 | D-Galactose | Show | | YMDB00286 | D-Glucose | Show | | YMDB00862 | hydron | Show |
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| GO Classification | | Component |
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| intrinsic to membrane | | integral to membrane | | cell part | | membrane | | membrane part | | Function |
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| transporter activity | | transmembrane transporter activity | | substrate-specific transmembrane transporter activity | | Process |
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| transmembrane transport | | establishment of localization | | transport |
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| Gene Properties |
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| Chromosome Location | chromosome 12 |
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| Locus | YLR081W |
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| Gene Sequence | >1725 bp
ATGGCAGTTGAGGAGAACAATGTGCCTGTTGTTTCACAGCAACCCCAAGCTGGTGAAGAC
GTGATCTCTTCACTCAGTAAAGATTCCCATTTAAGCGCACAATCTCAAAAGTATTCCAAT
GATGAATTGAAAGCCGGTGAGTCAGGGCCTGAAGGCTCCCAAAGTGTTCCTATAGAGATA
CCCAAGAAGCCCATGTCTGAATATGTTACCGTTTCCTTGCTTTGTTTGTGTGTTCGCTTC
GGCGGCTTCATGTTTGGCTGGGATACCAGTACTATTTCTGGGTTTGTTGTCCAAACAGAC
TTTTTGAGAAGGTTTGGTATGAAACATAAGGATGGTACCCACTATTTGTCAAACGTCAGA
ACAGGTTTAATCGTCGCCATTTTCAATATTGGCTGTGCCTTTGGTGGTATTATACTTTCC
AAAGGTGGAGATATGTATGGCCGTAAAAAGGGTCTTTCGATTGTCGTCTCGGTTTATATA
GTTGGTATTATCATTCAAATTGCCTCTATCAACAAGTGGTACCAATATTTCATTGGTAGA
ATCATATCTGGTTTGGGTGTCGGCGGCATCGCTGTCTTATGTCCTATGTTGATCTCTGAA
ATTGCTCCAAAGCACTTGAGAGGCACACTAGTTTCTTGTTATCAGCTGATGATTACTGCA
GGTATCTTTTTGGGCTACTGTACTAATTACGGTACAAAGAGCTATTCGAACTCAGTTCAA
TGGAGAGTTCCATTAGGGCTATGTTTCGCTTGGTCATTATTTATGATTGGCGCTTTGACG
TTAGTTCCTGAATCCCCACGTTATTTATGTGAGGTGAATAAGGTAGAAGACGCCAAGCGT
TCCATTGCTAAGTCTAACAAGGTGTCACCAGAGGATCCTGCCGTCCAGGCCGAGTTAGAT
CTGATCATGGCCGGTATAGAAGCTGAAAAACTGGCTGGCAATGCGTCCTGGGGGGAATTA
TTTTCCACCAAGACCAAAGTATTTCAACGTTTGTTGATGGGTGTGTTTGTTCAAATGTTC
CAACAATTAACCGGTAACAATTATTTTTTCTACTACGGTACCGTTATTTTCAAGTCAGTT
GGCCTGGATGATTCCTTTGAAACATCCATTGTCATTGGTGTAGTCAACTTTGCCTCCACT
TTCTTTAGTTTGTGGACTGTCGAAAACTTGGGGCGTCGTAAATGTTTACTTTTGGGCGCT
GCCACTATGATGGCTTGTATGGTCATCTACGCCTCTGTTGGTGTTACTAGATTATATCCT
CACGGTAAAAGCCAGCCATCTTCTAAAGGTGCCGGTAACTGTATGATTGTCTTTACCTGT
TTTTATATTTTCTGTTATGCCACAACCTGGGCGCCAGTTGCCTGGGTCATCACAGCAGAA
TCATTCCCACTGAGAGTCAAGTCGAAATGTATGGCGTTGGCCTCTGCTTCCAATTGGGTA
TGGGGGTTCTTGATTGCATTTTTCACCCCATTCATCACATCTGCCATTAACTTCTACTAC
GGTTATGTCTTCATGGGCTGTTTGGTTGCCATGTTTTTTTATGTCTTTTTCTTTGTTCCA
GAAACTAAAGGCCTATCGTTAGAAGAAATTCAAGAATTATGGGAAGAAGGTGTTTTACCT
TGGAAATCTGAAGGCTGGATTCCTTCATCCAGAAGAGGTAATAATTACGATTTAGAGGAT
TTACAACATGACGACAAACCGTGGTACAAGGCCATGCTAGAATAA |
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| Protein Properties |
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| Pfam Domain Function | |
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| Protein Residues | 574 |
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| Protein Molecular Weight | 63625.39844 |
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| Protein Theoretical pI | 7.3 |
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| Signalling Regions | |
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| Transmembrane Regions | - 71-91
- 122-142
- 150-170
- 176-196
- 208-228
- 243-263
- 343-362
- 367-387
- 395-415
- 436-456
- 473-493
- 500-520
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| Protein Sequence | >Galactose transporter
MAVEENNMPVVSQQPQAGEDVISSLSKDSHLSAQSQKYSNDELKAGESGSEGSQSVPIEI
PKKPMSEYVTVSLLCLCVAFGGFMFGWDTGTISGFVVQTDFLRRFGMKHKDGTHYLSNVR
TGLIVAIFNIGCAFGGIILSKGGDMYGRKKGLSIVVSVYIVGIIIQIASINKWYQYFIGR
IISGLGVGGIAVLCPMLISEIAPKHLRGTLVSCYQLMITAGIFLGYCTNYGTKSYSNSVQ
WRVPLGLCFAWSLFMIGALTLVPESPRYLCEVNKVEDAKRSIAKSNKVSPEDPAVQAELD
LIMAGIEAEKLAGNASWGELFSTKTKVFQRLLMGVFVQMFQQLTGNNYFFYYGTVIFKSV
GLDDSFETSIVIGVVNFASTFFSLWTVENLGHRKCLLLGAATMMACMVIYASVGVTRLYP
HGKSQPSSKGAGNCMIVFTCFYIFCYATTWAPVAWVITAESFPLRVKSKCMALASASNWV
WGFLIAFFTPFITSAINFYYGYVFMGCLVAMFFYVFFFVPETKGLSLEEIQELWEEGVLP
WKSEGWIPSSRRGNNYDLEDLQHDDKPWYKAMLE |
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| References |
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| External Links | |
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| General Reference | - Szkutnicka, K., Tschopp, J. F., Andrews, L., Cirillo, V. P. (1989). "Sequence and structure of the yeast galactose transporter." J Bacteriol 171:4486-4493.2666404
- Nehlin, J. O., Carlberg, M., Ronne, H. (1989). "Yeast galactose permease is related to yeast and mammalian glucose transporters." Gene 85:313-319.2697639
- Johnston, M., Hillier, L., Riles, L., Albermann, K., Andre, B., Ansorge, W., Benes, V., Bruckner, M., Delius, H., Dubois, E., Dusterhoft, A., Entian, K. D., Floeth, M., Goffeau, A., Hebling, U., Heumann, K., Heuss-Neitzel, D., Hilbert, H., Hilger, F., Kleine, K., Kotter, P., Louis, E. J., Messenguy, F., Mewes, H. W., Hoheisel, J. D., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome XII." Nature 387:87-90.9169871
- Kim, H., Melen, K., Osterberg, M., von Heijne, G. (2006). "A global topology map of the Saccharomyces cerevisiae membrane proteome." Proc Natl Acad Sci U S A 103:11142-11147.16847258
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