Protein GAL3 (P13045)

Identification
NameProtein GAL3
SynonymsNot Available
Gene NameGAL3
Enzyme ClassNot Available
Biological Properties
General Functionpositive regulation of transcription from RNA polymerase II promoter by galactose
Specific FunctionThe GAL3 regulatory function is required for rapid induction of the galactose system. At normal induction, galactose in the presence of the GAL3 protein may lead to the induction of the GAL genes, including GAL1. Then the galactokinase protein (GAL1) in the presence of galactose may reinforce the induction leading to a higher expression level. Upon depletion of galactose, the inducing activity of the galactokinase protein may decrease, after which transcription of the GAL genes, including GAL1, may decrease.
Cellular LocationNot Available
SMPDB Pathways
Leloir PathwayPW002397 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
ATP binding
nucleus
cytoplasm
galactokinase activity
galactose metabolic process
maintenance of protein location
positive regulation of transcription from RNA polymerase II promoter by galactose
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>1563 bp ATGAATACAAACGTTCCAATATTCAGTTCTCCGGTCAGAGATTTACCAAGGTCTTTCGAA CAAAAACATTTAGCGGTTGTAGATGCATTTTTCCAAACATACCATGTCAAACCTGATTTT ATCGCTAGGTCTCCTGGCAGAGTAAATCTGATTGGTGAGCATATAGATTATTGCGATTTT TCAGTTTTGCCATTAGCCATTGATGTGGATATGCTTTGCGCAGTTAAAATTTTAGACGAA AAAAATCCATCCATTACCTTAACAAATGCGGACCCTAAATTTGCTCAGCGAAAGTTTGAT CTGCCTTTAGATGGTTCCTACATGGCCATAGATCCGTCTGTGTCGGAATGGTCGAATTAC TTTAAATGCGGACTACATGTGGCACATTCATACTTGAAAAAAATTGCTCCGGAAAGATTT AATAATACACCCTTAGTAGGTGCGCAGATCTTTTGCCAGAGCGATATTCCTACTGGTGGT GGACTCTCATCTGCATTTACTTGCGCGGCAGCACTAGCCACAATTAGAGCCAATATGGGA AAAAATTTTGATATTTCCAAAAAAGACTTGACCCGCATCACAGCGGTTGCTGAGCACTAT GTTGGAGTCAATAATGGTGGTATGGATCAAGCAACGTCTGTTTATGGGGAAGAAGATCAT GCTCTATACGTAGAGTTTAGGCCAAAACTAAAGGCCACACCTTTCAAGTTTCCTCAATTG AAAAATCATGAAATCAGTTTCGTCATCGCCAATACTCTTGTAAAGTCTAATAAATTCGAA ACTGCTCCTACAAATTACAATTTAAGAGTAATAGAGGTAACAGTTGCTGCCAACGCCTTG GCGACCAGATACAGCGTGGCCTTACCATCTCACAAGGACAATTCTAACTCAGAAAGAGGG AATCTAAGAGATTTTATGGATGCTTACTACGCCAGATACGAAAACCAAGCCCAACCATGG AATGGAGATATCGGAACTGGTATTGAACGTTTACTCAAGATGCTACAATTGGTAGAAGAA TCTTTCTCGAGGAAAAAGAGCGGATTCACTGTACATGAAGCCTCTACGGCGCTAAACTGT TCACGTGAGGAGTTCACTAGAGATTACCTGACAACTTTTCCCGTCCGCTTCCAAGTCTTG AAACTATATCAAAGAGCTAAACACGTTTACTCCGAATCCTTAAGGGTGCTTAAGGCTTTA AAAATGATGACAAGTGCCACTTTTCACACGGACGAAGATTTCTTTACAGATTTTGGCCGA CTAATGAATGAGTCCCAGGCCTCTTGTGATAAACTTTATGAATGTTCGTGCATAGAAACC AATCAAATATGCTCGATTGCCCTAGCAAATGGTTCTTTCGGCTCCCGTCTCACTGGCGCT GGTTGGGGCGGTTGCACTATCCACCTTGTTCCTAGTGGCGCTAATGGGAACGTGGAACAG GTACGAAAAGCACTAATCGAAAAATTCTACAATGTAAGATATCCGGATCTCACAGATGAA GAACTAAAAGACGCAATTATAGTTTCGAAGCCTGCCTTGGGTACTTGTTTGTACGAACAA TAA
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues520
Protein Molecular Weight58128.505
Protein Theoretical pINot Available
PDB Fileshow
Signalling RegionsNot Available
Transmembrane RegionsNot Available
Protein Sequence>Protein GAL3 MNTNVPIFSSPVRDLPRSFEQKHLAVVDAFFQTYHVKPDFIARSPGRVNLIGEHIDYCDF SVLPLAIDVDMLCAVKILDEKNPSITLTNADPKFAQRKFDLPLDGSYMAIDPSVSEWSNY FKCGLHVAHSYLKKIAPERFNNTPLVGAQIFCQSDIPTGGGLSSAFTCAAALATIRANMG KNFDISKKDLTRITAVAEHYVGVNNGGMDQATSVYGEEDHALYVEFRPKLKATPFKFPQL KNHEISFVIANTLVKSNKFETAPTNYNLRVIEVTVAANALATRYSVALPSHKDNSNSERG NLRDFMDAYYARYENQAQPWNGDIGTGIERLLKMLQLVEESFSRKKSGFTVHEASTALNC SREEFTRDYLTTFPVRFQVLKLYQRAKHVYSESLRVLKALKMMTSATFHTDEDFFTDFGR LMNESQASCDKLYECSCIETNQICSIALANGSFGSRLTGAGWGGCTIHLVPSGANGNVEQ VRKALIEKFYNVRYPDLTDEELKDAIIVSKPALGTCLYEQ
References
External Links
ResourceLink
Saccharomyces Genome Database GAL3
Uniprot IDP13045
Uniprot NameGAL3
PDB ID
3V2U
General ReferenceNot Available